N,N-dimethyltransferase - Streptomyces venezuelae

Preferred order of sections

Names and origin

Protein names

Submitted name:
N,N-dimethyltransferase EMBL AAC68678.1

Gene names

Name:

desVI EMBL AAC68678.1

Organism

Streptomyces venezuelae EMBL AAC68678.1

Taxonomic identifier

54571 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	237 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine PDB 3BXO
Molecular function	Methyltransferase EMBL AAC68678.1 Transferase
Technical term	3D-structure PDB 3BXO
Gene Ontology (GO)
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Region

46 – 47

2

S-adenosyl-L-methionine binding PDB 3BXO

Region

89 – 90

2

S-adenosyl-L-methionine binding PDB 3BXO

Sites

Binding site

21

1

S-adenosyl-L-methionine PDB 3BXO

Binding site

67

1

S-adenosyl-L-methionine PDB 3BXO

Binding site

105

1

S-adenosyl-L-methionine; via carbonyl oxygen PDB 3BXO

Sequences

Sequence

Length

Mass (Da)

Tools

Q9ZGH6 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 156E67A0E7406AE8
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FASTA

237

25,979

        10         20         30         40         50         60 
MYEVDHADVY DLFYLGRGKD YAAEASDIAD LVRSRTPEAS SLLDVACGTG THLEHFTKEF 

        70         80         90        100        110        120 
GDTAGLELSE DMLTHARKRL PDATLHQGDM RDFRLGRKFS AVVSMFSSVG YLKTTEELGA 

       130        140        150        160        170        180 
AVASFAEHLE PGGVVVVEPW WFPETFADGW VSADVVRRDG RTVARVSHSV REGNATRMEV 

       190        200        210        220        230 
HFTVADPGKG VRHFSDVHLI TLFHQAEYEA AFTAAGLRVE YLEGGPSGRG LFVGVPA

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References

[1]	"A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity." Xue Y., Zhao L., Liu H.W., Sherman D.H. Proc. Natl. Acad. Sci. U.S.A. 95:12111-12116(1998) [PubMed: 9770448] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC15439 EMBL AAC68678.1.
[2]	"Three-dimensional structure of DesVI from Streptomyces venezuelae: a sugar N,N-dimethyltransferase required for dTDP-desosamine biosynthesis." Burgie E.S., Holden H.M. Biochemistry 47:3982-3988(2008) [PubMed: 18327916] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-L-METHIONINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF079762 Genomic DNA. Translation: AAC68678.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3BXO	X-ray	2.00	A/B	1-237	[»]

ProteinModelPortal

Q9ZGH6.

SMR

Q9ZGH6. Positions 2-237.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

ProtoNet

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Entry information

Entry name

Q9ZGH6_9ACTO

Accession

Primary (citable) accession number: Q9ZGH6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	July 27, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)