Q9ZGH0 (Q9ZGH0_9ACTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-dehydrase EMBL AAC68684.1

Gene names

Name:

desI EMBL AAC68684.1

Organism

Streptomyces venezuelae EMBL AAC68684.1

Taxonomic identifier

54571 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	415 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the degT/dnrJ/eryC1 family. RuleBase RU004508

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004509
Technical term	3D-structure PDB 2PO3
Gene Ontology (GO)
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9ZGH0 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 6B3D044A1207C443	FASTA	415	44,292
	10 20 30 40 50 60 MKSALSDLAF FGGPAAFDQP LLVGRPNRID RARLYERLDR ALDSQWLSNG GPLVREFEER 70 80 90 100 110 120 VAGLAGVRHA VATCNATAGL QLLAHAAGLT GEVIMPSMTF AATPHALRWI GLTPVFADID 130 140 150 160 170 180 PDTGNLDPDQ VAAAVTPRTS AVVGVHLWGR PCAADQLRKV ADEHGLRLYF DAAHALGCAV 190 200 210 220 230 240 DGRPAGSLGD AEVFSFHATK AVNAFEGGAV VTDDADLAAR IRALHNFGFD LPGGSPAGGT 250 260 270 280 290 300 NAKMSEAAAA MGLTSLDAFP EVIDRNRRNH AAYREHLADL PGVLVADHDR HGLNNHQYVI 310 320 330 340 350 360 VEIDEATTGI HRDLVMEVLK AEGVHTRAYF SPGCHELEPY RGQPHAPLPH TERLAARVLS 370 380 390 400 410 LPTGTAIGDD DIRRVADLLR LCATRGRELT ARHRDTAPAP LAAPQTSTPT IGRSR

References

[1]	"A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity." Xue Y., Zhao L., Liu H.W., Sherman D.H. Proc. Natl. Acad. Sci. U.S.A. 95:12111-12116(1998) [PubMed: 9770448] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC15439 EMBL AAC68684.1.
[2]	"Molecular architecture of DesI: a key enzyme in the biosynthesis of desosamine." Burgie E.S., Holden H.M. Biochemistry 46:8999-9006(2007) [PubMed: 17630700] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF079762 Genomic DNA. Translation: AAC68684.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2PO3	X-ray	2.10	A/B	1-415	[»]

ProteinModelPortal

Q9ZGH0.

SMR

Q9ZGH0. Positions 3-395.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR000653. DegT/StrS_aminotransferase.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]

Gene3D

G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.

Pfam

PF01041. DegT_DnrJ_EryC1. 1 hit.
[Graphical view]

PIRSF

PIRSF000390. PLP_StrS. 1 hit.

SUPFAM

SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9ZGH0_9ACTO

Accession

Primary (citable) accession number: Q9ZGH0

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	March 8, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)