Q9ZFV4 (EUTT_SALTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ethanolamine utilization cobalamin adenosyltransferase
EC=2.5.1.17

Gene names

Name:	eutT
Ordered Locus Names:	STM2467

Organism

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]

Taxonomic identifier

99287 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella typhimurium

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts CNB12 to ADOB12 By similarity.
Catalytic activity	ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide. ATP + cobinamide = triphosphate + adenosylcobinamide.
Pathway	Amine and polyamine degradation; ethanolamine degradation.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cobalamin biosynthetic process Inferred from electronic annotation. Source: InterPro ethanolamine catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cob(I)yrinic acid a,c-diamide adenosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	Ethanolamine utilization cobalamin adenosyltransferase		PRO_0000087101

Sequences

	Sequence		Length	Mass (Da)
	Q9ZFV4 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 9502A28FDB4DC9E4	FASTA	267	30,239
	10 20 30 40 50 60 MNDFITETWL RANHTLSEGS EIHLPADARL TPSARELLES RRLRIKFLDP QGRLFVDDDE 70 80 90 100 110 120 QQPQPVHGLT SSDTHPQACC ELCRQPVVKK PDTLTHLTAD KMVAKSDPRL GFRAALDSAI 130 140 150 160 170 180 ALTVWLQIEL AEPWQPWLFD IRSRLGNIMR ADAIDEPLAA QSIVGLNEDE LHRLSHQPLR 190 200 210 220 230 240 YLDHDHLVPE ASHGRDAALL NLLRTKVRET ETLAAQVFIT RSFEVLRPDI LQALNRLSST 250 260 VYVMMILSVA KHPLTVAQIQ QRLGEKP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins." Kofoid E.C., Rappleye C.A., Stojiljkovic I., Roth J.R. J. Bacteriol. 181:5317-5329(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: LT2.
[2]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF093749 Genomic DNA. Translation: AAC78114.1. AE006468 Genomic DNA. Translation: AAL21361.1.
RefSeq	NP_461402.1. NC_003197.1.
3D structure databases
ProteinModelPortal	Q9ZFV4.
ModBase	Search...
Protein-protein interaction databases
STRING	99287.STM2467.
Proteomic databases
PaxDb	Q9ZFV4.
PRIDE	Q9ZFV4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL21361; AAL21361; STM2467.
GeneID	1253989.
KEGG	stm:STM2467.
PATRIC	32383565. VBISalEnt20916_2605.
Phylogenomic databases
eggNOG	COG4812.
HOGENOM	HOG000289182.
KO	K04032.
OMA	DIMQALN.
ProtClustDB	PRK15020.
Enzyme and pathway databases
UniPathway	UPA00560.
Family and domain databases
Gene3D	1.20.1200.10. 1 hit.
InterPro	IPR016030. AdoCbl_synth_CblAdoTrfase-like. IPR009194. AdoCbl_synth_CblAdoTrfase_EutT. [Graphical view]
Pfam	PF01923. Cob_adeno_trans. 1 hit. [Graphical view]
PIRSF	PIRSF012294. ATR_EutT. 1 hit.
SUPFAM	SSF89028. AdoCbl_synth_CblAdoTrfase-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EUTT_SALTY

Accession

Primary (citable) accession number: Q9ZFV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program