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Protein
Submitted name:

Exotoxin 1

Gene

set1

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Exotoxin 1Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:set1Imported
ORF Names:AL077_09650Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence analysisAdd
BLAST
Chaini31 – 231201Sequence analysisPRO_5007217135Add
BLAST

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V1OX-ray2.75A/B31-231[»]
1V1PX-ray2.70A/B39-231[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 12682SSL_OBInterPro annotationAdd
BLAST
Domaini142 – 20968Stap_Strp_tox_CInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.10.20.120. 1 hit.
InterProiIPR008992. Enterotoxin.
IPR015282. SSL_OB.
IPR006126. Staph/Strept_toxin_CS.
IPR008375. Staph_exotoxin.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view]
PfamiPF09199. SSL_OB. 1 hit.
PF02876. Stap_Strp_tox_C. 1 hit.
[Graphical view]
PRINTSiPR01898. SAGSUPRFAMLY.
PR01800. STAPHEXOTOXN.
PR01501. TOXICSSTOXIN.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZFS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKTLAKAT LALGLLTTGV ITSEGQAVQA AEKQERVQHL HDIRDLHRYY
60 70 80 90 100
SSESFEYSNV SGKVENYNGS NVVRFNPKDQ NHQLFLLGKD KEQYKEGLQG
110 120 130 140 150
QNVFVVQELI DPNGRLSTVG GVTKKNNKTS ETNTPLFVNK VNGEDLDASI
160 170 180 190 200
DSFLIQKEEI SLKELDFKIR QQLVNNYGLY KGTSKYGKII INLKDENKVE
210 220 230
IDLGDKLQFE RMGDVLNSKD IRGISVTINQ I
Length:231
Mass (Da):26,051
Last modified:May 1, 1999 - v1
Checksum:i1710902412510102
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF094826 Genomic DNA. Translation: AAC69192.1.
AF188835 Genomic DNA. Translation: AAF05587.1.
LIGV01000014 Genomic DNA. Translation: KQB70061.1.
RefSeqiWP_000769829.1. NZ_LN626917.1.

Genome annotation databases

EnsemblBacteriaiKLM35071; KLM35071; RK78_04920.
KLM85197; KLM85197; RK90_13975.
KLM87031; KLM87031; RK88_09200.
KLN16799; KLN16799; RL03_10395.
KQB70061; KQB70061; AL077_09650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF094826 Genomic DNA. Translation: AAC69192.1.
AF188835 Genomic DNA. Translation: AAF05587.1.
LIGV01000014 Genomic DNA. Translation: KQB70061.1.
RefSeqiWP_000769829.1. NZ_LN626917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V1OX-ray2.75A/B31-231[»]
1V1PX-ray2.70A/B39-231[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKLM35071; KLM35071; RK78_04920.
KLM85197; KLM85197; RK90_13975.
KLM87031; KLM87031; RK88_09200.
KLN16799; KLN16799; RL03_10395.
KQB70061; KQB70061; AL077_09650.

Family and domain databases

Gene3Di3.10.20.120. 1 hit.
InterProiIPR008992. Enterotoxin.
IPR015282. SSL_OB.
IPR006126. Staph/Strept_toxin_CS.
IPR008375. Staph_exotoxin.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
[Graphical view]
PfamiPF09199. SSL_OB. 1 hit.
PF02876. Stap_Strp_tox_C. 1 hit.
[Graphical view]
PRINTSiPR01898. SAGSUPRFAMLY.
PR01800. STAPHEXOTOXN.
PR01501. TOXICSSTOXIN.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiPS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of a novel gene cluster encoding staphylococcal exotoxin-like proteins: characterization of the prototypic gene and its protein product, SET1."
    Williams R.J., Ward J.M., Henderson B., Poole S., O'Hara B.P., Wilson M., Nair S.P.
    Infect. Immun. 68:4407-4415(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NCTC6571Imported.
  2. "Structural relationships and cellular tropism of staphylococcal superantigen-like proteins."
    Al-Shangiti A.M., Naylor C.E., Nair S.P., Briggs D.C., Henderson B., Chain B.M.
    Infect. Immun. 72:4261-4270(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 39-231.
  3. "Analysis of methicillin-resistant Staphylococcus aureus ST5 and ST30 strains colonizing healthy children in public daycare centers in Niteroi, Brazil."
    Stephens C.M., Cho P.J., Braga E.D., Cardoso C.A., Riley L.W., Alves F.A.
    Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CC175Imported.

Entry informationi

Entry nameiQ9ZFS5_STAAU
AccessioniPrimary (citable) accession number: Q9ZFS5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.