Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ZFA3

- SYE1_RHOS4

UniProt

Q9ZFA3 - SYE1_RHOS4

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate--tRNA ligase 1

Gene

gltX1

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei246 – 2461ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSPH272943:GJAS-596-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase 1UniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetase 1UniRule annotation
Short name:
GluRS 1UniRule annotation
Gene namesi
Name:gltX1UniRule annotation
Synonyms:gluS
Ordered Locus Names:RHOS4_05770
ORF Names:RSP_1995
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000002703: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 471471Glutamate--tRNA ligase 1PRO_0000119637Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi272943.RSP_1995.

Structurei

3D structure databases

ProteinModelPortaliQ9ZFA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi15 – 2511"HIGH" regionAdd
BLAST
Motifi243 – 2475"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000252722.
KOiK01885.
OMAiAMGWEVP.
OrthoDBiEOG6DRPF7.
PhylomeDBiQ9ZFA3.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZFA3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPAASDKPVV TRFAPSPTGY LHIGGGRTAL FNWLYARGRK GTFLLRIEDT
60 70 80 90 100
DRERSTPEAT DAILRGLTWL GLDWDGEVVS QFARKDRHAE VAREMLERGA
110 120 130 140 150
AYKCFSTQEE IEAFRESARA EGRSTLFRSP WRDADPTSHP DAPFVIRMKA
160 170 180 190 200
PRSGETVIED EVQGTVRFQN ETLDDMVVLR SDGTPTYMLA VVVDDHDMGV
210 220 230 240 250
THVIRGDDHL NNAARQTMVY EAMGWEVPVW AHIPLIHGPD GKKLSKRHGA
260 270 280 290 300
LGVEEYQAMG YPAAGMRNYL ARLGWSHGDD EFFTSEQAMD WFDLGGIGRS
310 320 330 340 350
PARLDFKKLE SVCGQHIAVM EDAELMREIA AYLAAARKPA LTDLQAARLE
360 370 380 390 400
KGLYALKDRA KTFPELLEKA RFALESRPIV ADDAAAKALD PVSRGILREL
410 420 430 440 450
TPMLQAASWS KQDLEAILTA FASEKGMGFG KLAAPLRTAL AGRTVTPSVY
460 470
DMMLVIGRDE TIARLEDAAA A
Length:471
Mass (Da):52,136
Last modified:May 1, 1999 - v1
Checksum:i044E8C102AB5FCB9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF108766 Genomic DNA. Translation: AAD09123.1.
CP000143 Genomic DNA. Translation: ABA78145.1.
PIRiT46860.
RefSeqiWP_011337143.1. NZ_AKVW01000001.1.
YP_352046.1. NC_007493.2.

Genome annotation databases

EnsemblBacteriaiABA78145; ABA78145; RSP_1995.
GeneIDi3719328.
KEGGirsp:RSP_1995.
PATRICi23150974. VBIRhoSph57909_0884.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF108766 Genomic DNA. Translation: AAD09123.1 .
CP000143 Genomic DNA. Translation: ABA78145.1 .
PIRi T46860.
RefSeqi WP_011337143.1. NZ_AKVW01000001.1.
YP_352046.1. NC_007493.2.

3D structure databases

ProteinModelPortali Q9ZFA3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272943.RSP_1995.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA78145 ; ABA78145 ; RSP_1995 .
GeneIDi 3719328.
KEGGi rsp:RSP_1995.
PATRICi 23150974. VBIRhoSph57909_0884.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000252722.
KOi K01885.
OMAi AMGWEVP.
OrthoDBi EOG6DRPF7.
PhylomeDBi Q9ZFA3.

Enzyme and pathway databases

BioCyci RSPH272943:GJAS-596-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Trp-ing up paradigms: distribution of tryptophan biosynthesis genes in Rhodobacter sphaeroides 2.4.1."
    Simmons A.E., Mackenzie R.C., Kaplan S.
    Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Entry informationi

Entry nameiSYE1_RHOS4
AccessioniPrimary (citable) accession number: Q9ZFA3
Secondary accession number(s): Q3J4Y9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3