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Q9ZEC2

- ATPL_RICPR

UniProt

Q9ZEC2 - ATPL_RICPR

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Protein
ATP synthase subunit c
Gene
atpE, RP022
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation By similarity.UniRule annotation
Key component of the F0 channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F1 delta and epsilon subunits By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei58 – 581Reversibly protonated during proton transport By similarity

GO - Molecular functioni

  1. hydrogen ion transmembrane transporter activity Source: InterPro
  2. lipid binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. ATP hydrolysis coupled proton transport Source: InterPro
  2. ATP synthesis coupled proton transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Keywords - Ligandi

Lipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit c
Alternative name(s):
ATP synthase F(0) sector subunit c
F-type ATPase subunit c
Short name:
F-ATPase subunit c
Lipid-binding protein
Gene namesi
Name:atpE
Ordered Locus Names:RP022
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821Helical; Reviewed prediction
Add
BLAST
Transmembranei52 – 7221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
  3. proton-transporting ATP synthase complex, coupling factor F(o) Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(0), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7474ATP synthase subunit cUniRule annotation
PRO_0000112161Add
BLAST

Interactioni

Subunit structurei

F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Protein-protein interaction databases

STRINGi272947.RP022.

Structurei

3D structure databases

ProteinModelPortaliQ9ZEC2.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase C chain family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0636.
HOGENOMiHOG000235245.
KOiK02110.
OMAiKVNLWNS.
OrthoDBiEOG68H8G3.

Family and domain databases

Gene3Di1.20.20.10. 1 hit.
HAMAPiMF_01396. ATP_synth_c_bact.
InterProiIPR000454. ATPase_F0-cplx_csu.
IPR020537. ATPase_F0-cplx_csu_DDCD_BS.
IPR002379. ATPase_proteolipid_c_like_dom.
[Graphical view]
PfamiPF00137. ATP-synt_C. 1 hit.
[Graphical view]
PRINTSiPR00124. ATPASEC.
SUPFAMiSSF81333. SSF81333. 1 hit.
PROSITEiPS00605. ATPASE_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZEC2-1 [UniParc]FASTAAdd to Basket

« Hide

MDIVSLKFIG IGFMAIGMYG AALGVSNIFS SLLSAIARNP SAAENLQRMA   50
LIGAGLAEAM GLFSFVIAML LIFS 74
Length:74
Mass (Da):7,686
Last modified:May 1, 1999 - v1
Checksum:i7AA5D0812840067A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235270 Genomic DNA. Translation: CAA14493.1.
PIRiF71709.
RefSeqiNP_220416.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14493; CAA14493; CAA14493.
GeneIDi883547.
KEGGirpr:RP022.
PATRICi17900776. VBIRicPro72556_0022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235270 Genomic DNA. Translation: CAA14493.1 .
PIRi F71709.
RefSeqi NP_220416.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZEC2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272947.RP022.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA14493 ; CAA14493 ; CAA14493 .
GeneIDi 883547.
KEGGi rpr:RP022.
PATRICi 17900776. VBIRicPro72556_0022.

Phylogenomic databases

eggNOGi COG0636.
HOGENOMi HOG000235245.
KOi K02110.
OMAi KVNLWNS.
OrthoDBi EOG68H8G3.

Family and domain databases

Gene3Di 1.20.20.10. 1 hit.
HAMAPi MF_01396. ATP_synth_c_bact.
InterProi IPR000454. ATPase_F0-cplx_csu.
IPR020537. ATPase_F0-cplx_csu_DDCD_BS.
IPR002379. ATPase_proteolipid_c_like_dom.
[Graphical view ]
Pfami PF00137. ATP-synt_C. 1 hit.
[Graphical view ]
PRINTSi PR00124. ATPASEC.
SUPFAMi SSF81333. SSF81333. 1 hit.
PROSITEi PS00605. ATPASE_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiATPL_RICPR
AccessioniPrimary (citable) accession number: Q9ZEC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi