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Q9ZEC1 (ATP6_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP synthase subunit a
Alternative name(s):
ATP synthase F0 sector subunit a
F-ATPase subunit 6
Gene names
Name:atpB
Ordered Locus Names:RP023
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity. HAMAP-Rule MF_01393

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01393.

Sequence similarities

Belongs to the ATPase A chain family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242ATP synthase subunit a HAMAP-Rule MF_01393
PRO_0000082069

Regions

Transmembrane29 – 4921Helical; Potential
Transmembrane84 – 10421Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane140 – 16021Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane210 – 23021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9ZEC1 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 488EE81DE6088613

FASTA24227,378
        10         20         30         40         50         60 
MTHSPLIQFN IKKLIDIKMF GFDVSFTNSS IYMLLATTLS LTYLYLAFYN RKLIPSRLQV 

        70         80         90        100        110        120 
SAEIVYNLVA DMLNQNIGIK GRKFIPLVFS LFIFILFCNL LGMTPYSFTA TSHIIVTFTL 

       130        140        150        160        170        180 
ALLIFLTVTI VGFIKHGVSF LTLFLPHGTP VWLAPLMIVI ELFTYLARPV SLSLRLAANM 

       190        200        210        220        230        240 
MAGHVLLKVI ASFTVSLMIY LKFLPIPLMV ILIGFEIFIA ILQAYIFTIL SCMYLNDAIN 


LH 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235270 Genomic DNA. Translation: CAA14494.1.
PIRG71709.
RefSeqNP_220417.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZEC1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP023.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA14494; CAA14494; CAA14494.
GeneID883548.
KEGGrpr:RP023.
PATRIC17900778. VBIRicPro72556_0023.

Phylogenomic databases

eggNOGCOG0356.
HOGENOMHOG000253874.
KOK02108.
OMAFDISFTN.
OrthoDBEOG6K4054.
ProtClustDBPRK05815.

Family and domain databases

Gene3D1.20.120.220. 1 hit.
HAMAPMF_01393. ATP_synth_a_bact.
InterProIPR000568. ATPase_F0-cplx_asu.
IPR023011. ATPase_F0-cplx_asu_AS.
[Graphical view]
PANTHERPTHR11410. PTHR11410. 1 hit.
PfamPF00119. ATP-synt_A. 1 hit.
[Graphical view]
PRINTSPR00123. ATPASEA.
SUPFAMSSF81336. SSF81336. 1 hit.
TIGRFAMsTIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITEPS00449. ATPASE_A. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATP6_RICPR
AccessionPrimary (citable) accession number: Q9ZEC1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names