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Protein

ATP synthase subunit a

Gene

atpB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyciRPRO272947:G1GT0-23-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit aUniRule annotation
Alternative name(s):
ATP synthase F0 sector subunit aUniRule annotation
F-ATPase subunit 6UniRule annotation
Gene namesi
Name:atpBUniRule annotation
Ordered Locus Names:RP023
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 49HelicalUniRule annotationAdd BLAST21
Transmembranei84 – 104HelicalUniRule annotationAdd BLAST21
Transmembranei114 – 134HelicalUniRule annotationAdd BLAST21
Transmembranei140 – 160HelicalUniRule annotationAdd BLAST21
Transmembranei189 – 209HelicalUniRule annotationAdd BLAST21
Transmembranei210 – 230HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(0), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000820691 – 242ATP synthase subunit aAdd BLAST242

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

Protein-protein interaction databases

STRINGi272947.RP023

Structurei

3D structure databases

ProteinModelPortaliQ9ZEC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase A chain family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EE4 Bacteria
COG0356 LUCA
HOGENOMiHOG000253874
KOiK02108
OMAiGMFPYFF

Family and domain databases

Gene3Di1.20.120.220, 1 hit
HAMAPiMF_01393 ATP_synth_a_bact, 1 hit
InterProiView protein in InterPro
IPR000568 ATP_synth_F0_asu
IPR023011 ATP_synth_F0_asu_AS
IPR035908 F0_ATP_A_sf
PfamiView protein in Pfam
PF00119 ATP-synt_A, 1 hit
PRINTSiPR00123 ATPASEA
SUPFAMiSSF81336 SSF81336, 1 hit
TIGRFAMsiTIGR01131 ATP_synt_6_or_A, 1 hit
PROSITEiView protein in PROSITE
PS00449 ATPASE_A, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZEC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSPLIQFN IKKLIDIKMF GFDVSFTNSS IYMLLATTLS LTYLYLAFYN
60 70 80 90 100
RKLIPSRLQV SAEIVYNLVA DMLNQNIGIK GRKFIPLVFS LFIFILFCNL
110 120 130 140 150
LGMTPYSFTA TSHIIVTFTL ALLIFLTVTI VGFIKHGVSF LTLFLPHGTP
160 170 180 190 200
VWLAPLMIVI ELFTYLARPV SLSLRLAANM MAGHVLLKVI ASFTVSLMIY
210 220 230 240
LKFLPIPLMV ILIGFEIFIA ILQAYIFTIL SCMYLNDAIN LH
Length:242
Mass (Da):27,378
Last modified:May 1, 1999 - v1
Checksum:i488EE81DE6088613
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235270 Genomic DNA Translation: CAA14494.1
PIRiG71709
RefSeqiNP_220417.1, NC_000963.1
WP_004596667.1, NC_000963.1

Genome annotation databases

EnsemblBacteriaiCAA14494; CAA14494; CAA14494
GeneIDi883548
KEGGirpr:RP023
PATRICifig|272947.5.peg.23

Similar proteinsi

Entry informationi

Entry nameiATP6_RICPR
AccessioniPrimary (citable) accession number: Q9ZEC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: April 25, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health