Q9ZEB6 (RECF_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA replication and repair protein RecF

Gene names

Name:	recF
Ordered Locus Names:	RP029

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity. HAMAP-Rule MF_00365
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00365.
Sequence similarities	Belongs to the RecF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	DNA replication and repair protein RecF HAMAP-Rule MF_00365		PRO_0000196450
Regions
	Nucleotide binding	33 – 40	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9ZEB6 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 500B37B88D77A16D	FASTA	360	41,489
	10 20 30 40 50 60 MKNIFLHSLT LENYRNFKNL ELKTDNTPII LTGENGSGKT NILEAISLFY PGRGLRSSKL 70 80 90 100 110 120 TDICKTSEDY CKVKTLLQSK LGLAELSTHI KRSSNRRITE YNASKIANNE LSKFTNMVWL 130 140 150 160 170 180 TPQMEGIFTS SSTDRRKFLD RIVYNFDTKH AALLNKYEYY MHERNKILAE DIRDNNWLKI 190 200 210 220 230 240 IEEKMADISN NIANNRLKTI RFIQQAIDDI ENEFPKADLS IDGIIEQKIL NVEGDIVNFI 250 260 270 280 290 300 ITELYKTRSK DKLLGRTSFG IHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEINST 310 320 330 340 350 360 IKLTKITPIL LLDEIFVHLD DKRRQYLMGF FNALNIQLWV TATDLDGIEN FANKAQLIKL

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14500.1.
PIR	E71710.
RefSeq	NP_220423.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZEB6.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP029.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA14500; CAA14500; CAA14500.
GeneID	883560.
KEGG	rpr:RP029.
PATRIC	17900790. VBIRicPro72556_0029.
Phylogenomic databases
eggNOG	COG1195.
HOGENOM	HOG000269558.
KO	K03629.
OMA	AMRERNR.
ProtClustDB	PRK00064.
Family and domain databases
HAMAP	MF_00365. RecF.
InterPro	IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR027417. P-loop_NTPase. IPR003395. RecF/RecN/SMC. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
TIGRFAMs	TIGR00611. recf. 1 hit.
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_RICPR

Accession

Primary (citable) accession number: Q9ZEB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 29, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program