Q9ZEA8 (GCP_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	RP037

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 387	387	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000096972

Sequences

	Sequence		Length	Mass (Da)
	Q9ZEA8 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: AB974E50F138591D	FASTA	387	42,726
	10 20 30 40 50 60 MKKILGIESS CDDTAISIIT ERRKILSNII ISQNTEHAVF GGVVPEIAAR SHLSNLDQAL 70 80 90 100 110 120 KNVLKKSNTE LTEISAIAAT SGPGLIGGVI VGSMFARSLS SALKKPFIAI NHLEGHALTA 130 140 150 160 170 180 RLTDNISYPY LLLLASGGHC QFVAVLGLGK YKILGTTIDD AVGETFDKVA KMLNLSFPGG 190 200 210 220 230 240 PEIEKRAKLG NPHKYKFPKP IINSGNCNMS FSGLKTAVRT LIMNLKEVND SVINDIAASF 250 260 270 280 290 300 QFTIGAILSS KMQDAIRLYK QILNDYYEDI NHPTKLNLKS FRKDEFNWKP LECITRPKYR 310 320 330 340 350 360 IHIQNSYRSN LLNDTIVIAG GVAANKYLQE ILSDCTRPYG YRLIAPPMHL CTDNAAMIAY 370 380 AGLERYNNKL FSPLDFCPKA KWSLEDI

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14508.1.
PIR	E71711.
RefSeq	NP_220431.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZEA8.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883568.
GenomeReviews	Gene locus RP037 in contig AJ235269_GR.
KEGG	rpr:RP037.
PATRIC	17900808. VBIRicPro72556_0038.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	KDCNFSY.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	RPRO272947:RP037-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. IPR022437. RPE3. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 2 hits. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. TIGR03775. RPE3. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_RICPR

Accession

Primary (citable) accession number: Q9ZEA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program