Q9ZE99 (LGT_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Prolipoprotein diacylglyceryl transferase
EC=2.4.99.-

Gene names

Name:	lgt
Ordered Locus Names:	RP046

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins By similarity. HAMAP MF_01147
Pathway	Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer). HAMAP MF_01147
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01147.
Sequence similarities	Belongs to the lgt family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipoprotein biosynthetic process Inferred from electronic annotation. Source: InterPro protein lipoylation Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Prolipoprotein diacylglyceryl transferase HAMAP MF_01147		PRO_0000172664
Regions
	Transmembrane	18 – 38	21	Helical; Potential
	Transmembrane	64 – 84	21	Helical; Potential
	Transmembrane	101 – 121	21	Helical; Potential
	Transmembrane	126 – 146	21	Helical; Potential
	Transmembrane	181 – 201	21	Helical; Potential
	Transmembrane	210 – 230	21	Helical; Potential
	Transmembrane	237 – 257	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9ZE99 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 451588ABF12F58A3	FASTA	268	30,556
	10 20 30 40 50 60 MLNELNNLFM ILPNINPIIF SIGPFSISWY SLAYVVGILL GWFYATKIIE KFKPEITKKH 70 80 90 100 110 120 IDDFITYAII AIIVGGRLGY VLLYNPLKYF TNPIEILKTY EGGMSFHGAT IGIIMAAYLF 130 140 150 160 170 180 CQKYKINFLS LTDIITTVAP IGLFLGRIAN FINCELYGRI TNSSFGIIFP NSDLQPRHPS 190 200 210 220 230 240 QLYEAFFEGL ILFCILTYAV FRHDTLKKRG LNSGIYLIFY SLFRIIIEMF REPDIQIGFI 250 260 LDSLTMGQIL SAPMLLLGSY LICRSNPK

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14517.1.
PIR	F71712.
RefSeq	NP_220440.1. NC_000963.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883591.
GenomeReviews	Gene locus RP046 in contig AJ235269_GR.
KEGG	rpr:RP046.
PATRIC	17900826. VBIRicPro72556_0047.
Phylogenomic databases
HOGENOM	HBG450278.
OMA	IVEIFRV.
ProtClustDB	PRK00052.
Enzyme and pathway databases
BioCyc	RPRO272947:RP046-MONOMER.
Family and domain databases
HAMAP	MF_01147. Lgt. [Tree]
InterPro	IPR001640. Prolipoprot_diAcglycer_Trfase. [Graphical view]
KO	K13292.
Pfam	PF01790. LGT. 1 hit. [Graphical view]
TIGRFAMs	TIGR00544. Lgt. 1 hit.
PROSITE	PS01311. LGT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LGT_RICPR

Accession

Primary (citable) accession number: Q9ZE99

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program