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Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-15773.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:RP069
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 188188Deoxycytidine triphosphate deaminasePRO_0000156009Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP069.

Structurei

3D structure databases

ProteinModelPortaliQ9ZE77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiEAGWEGH.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZE77-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIMSDKWIK DAVMNQNMIR PFAAKQVRVH NKEKIISYGL SSYGYDARVS
60 70 80 90 100
NEFKIFTNIN STTVDPKNFS EYNLVDREVD ACIIPPNSFA LGRTIEYFKI
110 120 130 140 150
PRDVLVICVG KSTYARCGII VNVTPLEPEW EGHVTLEFSN TTPLPAKIYA
160 170 180
NEGACQFLFL KSDQICDTSY AERQGKYMKQ VGVTLPLT
Length:188
Mass (Da):21,277
Last modified:May 1, 1999 - v1
Checksum:i5356639F595C6589
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235270 Genomic DNA. Translation: CAA14540.1.
PIRiE71715.
RefSeqiNP_220463.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14540; CAA14540; CAA14540.
GeneIDi883638.
KEGGirpr:RP069.
PATRICi17900872. VBIRicPro72556_0070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235270 Genomic DNA. Translation: CAA14540.1.
PIRiE71715.
RefSeqiNP_220463.1. NC_000963.1.

3D structure databases

ProteinModelPortaliQ9ZE77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP069.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA14540; CAA14540; CAA14540.
GeneIDi883638.
KEGGirpr:RP069.
PATRICi17900872. VBIRicPro72556_0070.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiEAGWEGH.
OrthoDBiEOG67DPKR.

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.
BioCyciMetaCyc:MONOMER-15773.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiDCD_RICPR
AccessioniPrimary (citable) accession number: Q9ZE77
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: January 7, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.