Q9ZE76 (SECB_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	RP070

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity. HAMAP MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00821.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	Protein-export protein secB HAMAP MF_00821		PRO_0000055410

Sequences

	Sequence		Length	Mass (Da)
	Q9ZE76 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: C9B52A2339F594D2	FASTA	152	17,139
	10 20 30 40 50 60 MSTINTDTSE AMPHISVNAQ YIKDLSLENP SAPSSLAALD QRPQIDLSLD INITNLSEEN 70 80 90 100 110 120 FYEVELNIEA IARNEKYKLF QIELKYAGVF NLINIDSEQH PILLSVHCPA MIFPFARKII 130 140 150 ASCTQDAGFQ PLMIDPIDFG ALYHKKMSEH QN

References

[1]	"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14541.1.
PIR	F71715.
RefSeq	NP_220464.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZE76.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883636.
GenomeReviews	Gene locus RP070 in contig AJ235269_GR.
KEGG	rpr:RP070.
PATRIC	17900874. VBIRicPro72556_0071.
Phylogenomic databases
HOGENOM	HBG294212.
OMA	GFPPLMI.
ProtClustDB	PRK05751.
Enzyme and pathway databases
BioCyc	RPRO272947:RP070-MONOMER.
Family and domain databases
HAMAP	MF_00821. SecB. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
KO	K03071.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. SecB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_RICPR

Accession

Primary (citable) accession number: Q9ZE76

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program