Q9ZE42 (Y106_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein RP106

Gene names

Ordered Locus Names:

RP106

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	971 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the trbL/virB6 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein secretion by the type IV secretion system Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 971	947	Uncharacterized protein RP106		PRO_0000269215
Regions
	Transmembrane	611 – 631	21	Helical; Potential
	Transmembrane	721 – 741	21	Helical; Potential
	Transmembrane	753 – 773	21	Helical; Potential
	Transmembrane	795 – 815	21	Helical; Potential
	Transmembrane	832 – 852	21	Helical; Potential
	Transmembrane	865 – 885	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9ZE42 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: D0C2818FD9199B41	FASTA	971	108,760
	10 20 30 40 50 60 MQSNLLKVLG VLAIVATLVC FIFAALGMIG AVRVGNGCYM RYSKDGNGST DSITSTITLN 70 80 90 100 110 120 ANANYVNISK MLPDGTTKLI PDPNRYGEWL NTQVLVEKNQ SVNLQVVGQV SLCLAYLPKN 130 140 150 160 170 180 NLQFTERTRP GKSNLDDSGQ MIPIPRVQDA NSPPISLIMD AKNNEWRNIA ELYANDKVLV 190 200 210 220 230 240 SVSPNFANTD ATVDDVFKGV KVTKDCTQGK TSYYPICGKY SIYSGKYVTA CELKQNYWKG 250 260 270 280 290 300 NVHREECYCV FGCIYKEDSD PWVCDMANAA SHCCTSLVCD SLPAWINHYS NMPEAYKDDG 310 320 330 340 350 360 SFTFSWSDKS KNLLIEYEDL QCSNNVNIPP NGQCPDIVNN RSPKDKNYIG GVSCTSGICK 370 380 390 400 410 420 DGDFQKNRKF WYTADGKGGK GPTGLIYQMN DIGSVSQALP SKLEFAKFVP ETEQPPEYKD 430 440 450 460 470 480 KNGKYLYKVI YNIPFNSNIE KSYLQYRLWS PTSQDASKNT GGYVLNIKQT KCYRENGNSF 490 500 510 520 530 540 KDIFDDRGRV QYIIVKSSEN PNTSGKTYSP QGINVDSDGK SHFNANESGY IWMKILNDPS 550 560 570 580 590 600 NNLKDYKDSE GSYKVHFSTS LKVGSFTIKV MNPLLQLFKT KVQDAATSIF KNMVCYKATD 610 620 630 640 650 660 NSSCTNFFTY IKAILILYVM TYGAMFLLGF AKINQKELVI RIAKIGVVSG LINGNTFEFF 670 680 690 700 710 720 NNYLFDAITN FSDSIIANMS GYSLFTSTNT ISNPFMFLDA IMSKIFFSQT FIAQLLSLLS 730 740 750 760 770 780 LGLSGIIYFI ITFIAICIVI ITTLRAIAVY IMAFMATCIL IGIAPLFISF LLFDFTRYLF 790 800 810 820 830 840 DNWVRFTIRY MIEPVVMMAG IIVLTQLFTI YLDFVLGYSV CWKCTLPIKI PFIGTILPIA 850 860 870 880 890 900 LLNVPIFCIN WFAPWGMDYM SGMMGVNMQN IVALVIIAYG MYGYVEFSGR MVAKLTSAAG 910 920 930 940 950 960 PSATQIGGRM SHDAGQKVLS QIGMDYRTRQ GITGRAKSRL EQRNRTLEHA EQNSKKYKKR 970 IGENTNEETL K

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14575.1.
PIR	H71719.
RefSeq	NP_220498.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZE42.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883719.
GenomeReviews	Gene locus RP106 in contig AJ235269_GR.
KEGG	rpr:RP106.
PATRIC	17900952. VBIRicPro72556_0108.
Phylogenomic databases
HOGENOM	HBG586502.
OMA	YLDFVLG.
ProtClustDB	CLSK870746.
Enzyme and pathway databases
BioCyc	RPRO272947:RP106-MONOMER.
Family and domain databases
InterPro	IPR007688. Conjugal_tfr_TrbL/VirB6. [Graphical view]
KO	K03201.
Pfam	PF04610. TrbL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y106_RICPR

Accession

Primary (citable) accession number: Q9ZE42

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program