Q9ZE09 (GATC_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit C
Short name=Glu-ADT subunit C
EC=6.3.5.-

Gene names

Name:	gatC
Ordered Locus Names:	RP153

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) By similarity. HAMAP MF_00122
Catalytic activity	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. HAMAP MF_00122 ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate. HAMAP MF_00122
Subunit structure	Heterotrimer of A, B and C subunits By similarity. HAMAP MF_00122
Sequence similarities	Belongs to the GatC family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of translational fidelity Inferred from electronic annotation. Source: InterPro translation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Glutamyl-tRNA(Gln) amidotransferase subunit C HAMAP MF_00122		PRO_0000105328

Sequences

	Sequence		Length	Mass (Da)
	Q9ZE09 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 9640F6A44A685474	FASTA	100	11,344
	10 20 30 40 50 60 MITKEEAQKI AKLARLKFEK DIVEKFSTQL STIMNMINIL NEIDCKDIEP LTSVSNMNAR 70 80 90 100 MREDTVTSSD LSNKLFDNVS GNSAKLAKEV KYFITPKVVE

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235270 Genomic DNA. Translation: CAA14621.1.
PIR	F71725.
RefSeq	NP_220544.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZE09.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883823.
GenomeReviews	Gene locus RP153 in contig AJ235269_GR.
KEGG	rpr:RP153.
PATRIC	17901054. VBIRicPro72556_0158.
Phylogenomic databases
HOGENOM	HBG586403.
OMA	VSNMNAR.
ProtClustDB	PRK00034.
Enzyme and pathway databases
BioCyc	RPRO272947:RP153-MONOMER.
Family and domain databases
HAMAP	MF_00122. GatC. [Tree]
InterPro	IPR003837. Glu-tRNAGlntrans. [Graphical view]
KO	K02435.
Pfam	PF02686. Glu-tRNAGln. 1 hit. [Graphical view]
TIGRFAMs	TIGR00135. GatC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GATC_RICPR

Accession

Primary (citable) accession number: Q9ZE09

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program