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Protein

Ribosomal RNA small subunit methyltransferase E

Gene

rsmE

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).By similarity

Catalytic activityi

S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil(1498) in 16S rRNA.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciRPRO272947:G1GT0-171-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase E (EC:2.1.1.193)
Alternative name(s):
16S rRNA m3U1498 methyltransferase
Gene namesi
Name:rsmE
Ordered Locus Names:RP168
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001762161 – 198Ribosomal RNA small subunit methyltransferase EAdd BLAST198

Proteomic databases

PRIDEiQ9ZDZ5

Interactioni

Protein-protein interaction databases

STRINGi272947.RP168

Structurei

3D structure databases

ProteinModelPortaliQ9ZDZ5
SMRiQ9ZDZ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA methyltransferase RsmE family.Curated

Phylogenomic databases

eggNOGiENOG4105QF0 Bacteria
COG1385 LUCA
HOGENOMiHOG000015265
KOiK09761
OMAiERWESTV

Family and domain databases

Gene3Di3.40.1280.10, 1 hit
InterProiView protein in InterPro
IPR029028 Alpha/beta_knot_MTases
IPR015947 PUA-like_sf
IPR006700 rRNA_ssu_MeTrfase-E
IPR029026 tRNA_m1G_MTases_N
PANTHERiPTHR30027 PTHR30027, 1 hit
PfamiView protein in Pfam
PF04452 Methyltrans_RNA, 1 hit
PIRSFiPIRSF015601 MTase_slr0722, 1 hit
SUPFAMiSSF75217 SSF75217, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00046 TIGR00046, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZDZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYNRIYINS NLAENSKLEL ARDYVHYVKT VLRLKIHDSL RIFNGSDGEF
60 70 80 90 100
LAQITQIGKN NLSVVLKEQL KKAYIESALT LAVAIIKSDK LMLTINMATQ
110 120 130 140 150
LGITKIIPLI TRRCQFRTVN IERLMKCVIE ATEQSERLNP PIIEQAITLK
160 170 180 190
DYLKKNNNLI LYANEHEKVK HSILHISSLL SKDIAIIIGP EEGLLMMS
Length:198
Mass (Da):22,603
Last modified:May 1, 1999 - v1
Checksum:i2BC7763BE94C4760
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235270 Genomic DNA Translation: CAA14635.1
PIRiD71727
RefSeqiNP_220558.1, NC_000963.1
WP_010886222.1, NC_000963.1

Genome annotation databases

EnsemblBacteriaiCAA14635; CAA14635; CAA14635
GeneIDi883854
KEGGirpr:RP168
PATRICifig|272947.5.peg.173

Similar proteinsi

Entry informationi

Entry nameiRSME_RICPR
AccessioniPrimary (citable) accession number: Q9ZDZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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