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Q9ZDZ5

- RSME_RICPR

UniProt

Q9ZDZ5 - RSME_RICPR

Protein

Ribosomal RNA small subunit methyltransferase E

Gene

rsmE

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit By similarity.By similarity

    Catalytic activityi

    S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L-homocysteine + N(3)-methyluracil(1498) in 16S rRNA.

    GO - Molecular functioni

    1. methyltransferase activity Source: UniProtKB-KW

    GO - Biological processi

    1. rRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    rRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribosomal RNA small subunit methyltransferase E (EC:2.1.1.193)
    Alternative name(s):
    16S rRNA m3U1498 methyltransferase
    Gene namesi
    Name:rsmE
    Ordered Locus Names:RP168
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 198198Ribosomal RNA small subunit methyltransferase EPRO_0000176216Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272947.RP168.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZDZ5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNA methyltransferase RsmE family.Curated

    Phylogenomic databases

    eggNOGiCOG1385.
    HOGENOMiHOG000015265.
    KOiK09761.
    OMAiPRINLIQ.
    OrthoDBiEOG6FJNHQ.

    Family and domain databases

    Gene3Di3.40.1280.10. 1 hit.
    InterProiIPR029028. Alpha/beta_knot_MTases.
    IPR015947. PUA-like_domain.
    IPR006700. rRNA_ssu_MeTrfase-E.
    IPR029026. tRNA_m1G_MTases_N.
    [Graphical view]
    PfamiPF04452. Methyltrans_RNA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF015601. MTase_slr0722. 1 hit.
    SUPFAMiSSF75217. SSF75217. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsiTIGR00046. TIGR00046. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9ZDZ5-1 [UniParc]FASTAAdd to Basket

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    MKYNRIYINS NLAENSKLEL ARDYVHYVKT VLRLKIHDSL RIFNGSDGEF    50
    LAQITQIGKN NLSVVLKEQL KKAYIESALT LAVAIIKSDK LMLTINMATQ 100
    LGITKIIPLI TRRCQFRTVN IERLMKCVIE ATEQSERLNP PIIEQAITLK 150
    DYLKKNNNLI LYANEHEKVK HSILHISSLL SKDIAIIIGP EEGLLMMS 198
    Length:198
    Mass (Da):22,603
    Last modified:May 1, 1999 - v1
    Checksum:i2BC7763BE94C4760
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235270 Genomic DNA. Translation: CAA14635.1.
    PIRiD71727.
    RefSeqiNP_220558.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA14635; CAA14635; CAA14635.
    GeneIDi883854.
    KEGGirpr:RP168.
    PATRICi17901086. VBIRicPro72556_0173.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235270 Genomic DNA. Translation: CAA14635.1 .
    PIRi D71727.
    RefSeqi NP_220558.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZDZ5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP168.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA14635 ; CAA14635 ; CAA14635 .
    GeneIDi 883854.
    KEGGi rpr:RP168.
    PATRICi 17901086. VBIRicPro72556_0173.

    Phylogenomic databases

    eggNOGi COG1385.
    HOGENOMi HOG000015265.
    KOi K09761.
    OMAi PRINLIQ.
    OrthoDBi EOG6FJNHQ.

    Family and domain databases

    Gene3Di 3.40.1280.10. 1 hit.
    InterProi IPR029028. Alpha/beta_knot_MTases.
    IPR015947. PUA-like_domain.
    IPR006700. rRNA_ssu_MeTrfase-E.
    IPR029026. tRNA_m1G_MTases_N.
    [Graphical view ]
    Pfami PF04452. Methyltrans_RNA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF015601. MTase_slr0722. 1 hit.
    SUPFAMi SSF75217. SSF75217. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsi TIGR00046. TIGR00046. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiRSME_RICPR
    AccessioniPrimary (citable) accession number: Q9ZDZ5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3