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Q9ZDZ5 (RSME_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase E

EC=2.1.1.193
Alternative name(s):
16S rRNA m3U1498 methyltransferase
Gene names
Name:rsmE
Ordered Locus Names:RP168
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit By similarity.

Catalytic activity

S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L-homocysteine + N(3)-methyluracil(1498) in 16S rRNA.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the RNA methyltransferase RsmE family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Ribosomal RNA small subunit methyltransferase E
PRO_0000176216

Sequences

Sequence LengthMass (Da)Tools
Q9ZDZ5 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 2BC7763BE94C4760

FASTA19822,603
        10         20         30         40         50         60 
MKYNRIYINS NLAENSKLEL ARDYVHYVKT VLRLKIHDSL RIFNGSDGEF LAQITQIGKN 

        70         80         90        100        110        120 
NLSVVLKEQL KKAYIESALT LAVAIIKSDK LMLTINMATQ LGITKIIPLI TRRCQFRTVN 

       130        140        150        160        170        180 
IERLMKCVIE ATEQSERLNP PIIEQAITLK DYLKKNNNLI LYANEHEKVK HSILHISSLL 

       190 
SKDIAIIIGP EEGLLMMS 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235270 Genomic DNA. Translation: CAA14635.1.
PIRD71727.
RefSeqNP_220558.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZDZ5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP168.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA14635; CAA14635; CAA14635.
GeneID883854.
KEGGrpr:RP168.
PATRIC17901086. VBIRicPro72556_0173.

Phylogenomic databases

eggNOGCOG1385.
HOGENOMHOG000015265.
KOK09761.
OMAPRINLIQ.
OrthoDBEOG6FJNHQ.

Family and domain databases

Gene3D3.40.1280.10. 1 hit.
InterProIPR029028. Alpha/beta_knot_MTases.
IPR015947. PUA-like_domain.
IPR006700. rRNA_ssu_MeTrfase-E.
IPR029026. tRNA_m1G_MTases_N.
[Graphical view]
PfamPF04452. Methyltrans_RNA. 1 hit.
[Graphical view]
PIRSFPIRSF015601. MTase_slr0722. 1 hit.
SUPFAMSSF75217. SSF75217. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsTIGR00046. TIGR00046. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSME_RICPR
AccessionPrimary (citable) accession number: Q9ZDZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names