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Q9ZDZ5

- RSME_RICPR

UniProt

Q9ZDZ5 - RSME_RICPR

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Protein

Ribosomal RNA small subunit methyltransferase E

Gene

rsmE

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).By similarity

Catalytic activityi

S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L-homocysteine + N(3)-methyluracil(1498) in 16S rRNA.

GO - Molecular functioni

  1. methyltransferase activity Source: UniProtKB-KW

GO - Biological processi

  1. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase E (EC:2.1.1.193)
Alternative name(s):
16S rRNA m3U1498 methyltransferase
Gene namesi
Name:rsmE
Ordered Locus Names:RP168
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Ribosomal RNA small subunit methyltransferase EPRO_0000176216Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP168.

Structurei

3D structure databases

ProteinModelPortaliQ9ZDZ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA methyltransferase RsmE family.Curated

Phylogenomic databases

eggNOGiCOG1385.
HOGENOMiHOG000015265.
KOiK09761.
OMAiPRINLIQ.
OrthoDBiEOG6FJNHQ.

Family and domain databases

Gene3Di3.40.1280.10. 1 hit.
InterProiIPR029028. Alpha/beta_knot_MTases.
IPR015947. PUA-like_domain.
IPR006700. rRNA_ssu_MeTrfase-E.
IPR029026. tRNA_m1G_MTases_N.
[Graphical view]
PfamiPF04452. Methyltrans_RNA. 1 hit.
[Graphical view]
PIRSFiPIRSF015601. MTase_slr0722. 1 hit.
SUPFAMiSSF75217. SSF75217. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00046. TIGR00046. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZDZ5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYNRIYINS NLAENSKLEL ARDYVHYVKT VLRLKIHDSL RIFNGSDGEF
60 70 80 90 100
LAQITQIGKN NLSVVLKEQL KKAYIESALT LAVAIIKSDK LMLTINMATQ
110 120 130 140 150
LGITKIIPLI TRRCQFRTVN IERLMKCVIE ATEQSERLNP PIIEQAITLK
160 170 180 190
DYLKKNNNLI LYANEHEKVK HSILHISSLL SKDIAIIIGP EEGLLMMS
Length:198
Mass (Da):22,603
Last modified:May 1, 1999 - v1
Checksum:i2BC7763BE94C4760
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235270 Genomic DNA. Translation: CAA14635.1.
PIRiD71727.
RefSeqiNP_220558.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14635; CAA14635; CAA14635.
GeneIDi883854.
KEGGirpr:RP168.
PATRICi17901086. VBIRicPro72556_0173.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235270 Genomic DNA. Translation: CAA14635.1 .
PIRi D71727.
RefSeqi NP_220558.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZDZ5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272947.RP168.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA14635 ; CAA14635 ; CAA14635 .
GeneIDi 883854.
KEGGi rpr:RP168.
PATRICi 17901086. VBIRicPro72556_0173.

Phylogenomic databases

eggNOGi COG1385.
HOGENOMi HOG000015265.
KOi K09761.
OMAi PRINLIQ.
OrthoDBi EOG6FJNHQ.

Family and domain databases

Gene3Di 3.40.1280.10. 1 hit.
InterProi IPR029028. Alpha/beta_knot_MTases.
IPR015947. PUA-like_domain.
IPR006700. rRNA_ssu_MeTrfase-E.
IPR029026. tRNA_m1G_MTases_N.
[Graphical view ]
Pfami PF04452. Methyltrans_RNA. 1 hit.
[Graphical view ]
PIRSFi PIRSF015601. MTase_slr0722. 1 hit.
SUPFAMi SSF75217. SSF75217. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsi TIGR00046. TIGR00046. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiRSME_RICPR
AccessioniPrimary (citable) accession number: Q9ZDZ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3