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Q9ZDX3 (COX3_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Synonyms:coxC
Ordered Locus Names:RP191
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group ›

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Probable cytochrome c oxidase subunit 3
PRO_0000183887

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane89 – 10921Helical; Potential
Transmembrane174 – 19421Helical; Potential
Transmembrane212 – 23221Helical; Potential
Transmembrane256 – 27621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9ZDX3 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: A96D98054FA06151

FASTA27831,480
        10         20         30         40         50         60 
MNPNSNSITK SHLFHIVNPS PWPILTSFAL LLLVIGGISS MHGYKFNMYI LSAGVISVIY 

        70         80         90        100        110        120 
CLYSWWRDVV QEGIVEHQHT SPVRKGLKIG MVLFILTETV FFSVFFASFL KSSISPVGIL 

       130        140        150        160        170        180 
DGVWVVKQGI WPPPTIKTFD PFDIPFINTL ILLLSGTTIT GAHYALEEKN QKDCVTALAF 

       190        200        210        220        230        240 
TIVLGIFFTL MQVYEYYHAE FKFTDGIYAS NFYLATGFHG AHVVIGTIFL IVCYFRAKRG 

       250        260        270 
DFTTEGNGHL GFEFAAWYWH FVDVVWLFLF TFVYILGS

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ235270 Genomic DNA. Translation: CAA14657.1.
PIRB71730.
RefSeqNP_220580.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZDX3.
ModBaseSearch...

Protein-protein interaction databases

STRING272947.RP191.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA14657; CAA14657; CAA14657.
GeneID883890.
KEGGrpr:RP191.
PATRIC17901136. VBIRicPro72556_0198.

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02276.
OMAYFVPGPS.
ProtClustDBCLSK870788.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_RICPR
AccessionPrimary (citable) accession number: Q9ZDX3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names

SIMILARITY comments

Index of protein domains and families

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