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Q9ZDW5

- HSCA_RICPR

UniProt

Q9ZDW5 - HSCA_RICPR

Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB By similarity.By similarity

    GO - Molecular functioni

    1. ATPase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. iron-sulfur cluster assembly Source: InterPro
    2. protein folding Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Chaperone

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chaperone protein HscA homolog
    Gene namesi
    Name:hscA
    Ordered Locus Names:RP200
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 593593Chaperone protein HscA homologPRO_0000078644Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272947.RP200.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZDW5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the heat shock protein 70 family.Curated

    Phylogenomic databases

    eggNOGiCOG0443.
    HOGENOMiHOG000228136.
    KOiK04044.
    OMAiSIDTKFN.
    OrthoDBiEOG6JMMSV.

    Family and domain databases

    Gene3Di1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    HAMAPiMF_00679. HscA.
    InterProiIPR018181. Heat_shock_70_CS.
    IPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    IPR010236. ISC_FeS_clus_asmbl_HscA.
    [Graphical view]
    PfamiPF00012. HSP70. 1 hit.
    [Graphical view]
    PRINTSiPR00301. HEATSHOCK70.
    SUPFAMiSSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEiPS00329. HSP70_2. 1 hit.
    PS01036. HSP70_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZDW5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQIIEITEPK QTDFQQKLQI AVGIDFGTTN SLIAIATNRK VKIIKSIGDK    50
    ELIPTTIDFI NEDLIIGNNK GLHSIKRLFG KTLKEILNTT TLFSLVKDYL 100
    DINSSELKLN FANKKMRIAE IAAEVFIYLK NQAEKQLKNN ITKAVITVPA 150
    HFNDAARGEI MLAAKIAGFE VLRLIAEPTA AAYAYGLNKN QTGRYLVYDL 200
    GGGTFDVSIL NIQEGIFQVI ATNGDNMLGG DDIDVVITQY LCNKFDLPHS 250
    IETLQLAKKA KEILTYKESF NNDIISINKQ TLEQLISPLV ERTINITQEC 300
    LEQSGNPNID GVILVGGTTR IPLIKDELYK AFKIDILSDI DPDKAVVCGA 350
    ALQAENLITQ HTNSLLIDVV PLSLGIELYG GIVEKIITRN TPIPIAVIKE 400
    FTTYADNQTG IQFHILQGER EMAADCRSLA RFELKGLPPM KAGNIRVEVT 450
    FAIDADGILS VSAYEKISNI SHNIEIKPNH GINKTEIETM LKNAYKNAKI 500
    DYTTRLLQEA VIETEALMSS IERSIIKLTK LLSESEISII NALLDNIKDA 550
    VQTRDQILIK NSIKEFKSKI KKYLDTKLNI NDLRKCKNSN QIK 593
    Length:593
    Mass (Da):66,019
    Last modified:May 1, 1999 - v1
    Checksum:iAACB8D666AF55D21
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235270 Genomic DNA. Translation: CAA14665.1.
    PIRiB71731.
    RefSeqiNP_220588.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA14665; CAA14665; CAA14665.
    GeneIDi883905.
    KEGGirpr:RP200.
    PATRICi17901158. VBIRicPro72556_0209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235270 Genomic DNA. Translation: CAA14665.1 .
    PIRi B71731.
    RefSeqi NP_220588.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZDW5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP200.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA14665 ; CAA14665 ; CAA14665 .
    GeneIDi 883905.
    KEGGi rpr:RP200.
    PATRICi 17901158. VBIRicPro72556_0209.

    Phylogenomic databases

    eggNOGi COG0443.
    HOGENOMi HOG000228136.
    KOi K04044.
    OMAi SIDTKFN.
    OrthoDBi EOG6JMMSV.

    Family and domain databases

    Gene3Di 1.20.1270.10. 1 hit.
    2.60.34.10. 1 hit.
    HAMAPi MF_00679. HscA.
    InterProi IPR018181. Heat_shock_70_CS.
    IPR029048. HSP70_C.
    IPR029047. HSP70_peptide-bd.
    IPR013126. Hsp_70_fam.
    IPR010236. ISC_FeS_clus_asmbl_HscA.
    [Graphical view ]
    Pfami PF00012. HSP70. 1 hit.
    [Graphical view ]
    PRINTSi PR00301. HEATSHOCK70.
    SUPFAMi SSF100920. SSF100920. 1 hit.
    SSF100934. SSF100934. 1 hit.
    PROSITEi PS00329. HSP70_2. 1 hit.
    PS01036. HSP70_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiHSCA_RICPR
    AccessioniPrimary (citable) accession number: Q9ZDW5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3