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Q9ZDS2

- CYCM_RICPR

UniProt

Q9ZDS2 - CYCM_RICPR

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Protein
Cytochrome c homolog
Gene
cycM, RP253
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

May be involved in electron transfer from bc1 complex to aa3 By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei84 – 841Heme (covalent) By similarity
Binding sitei87 – 871Heme (covalent) By similarity
Metal bindingi88 – 881Iron (heme axial ligand) By similarity
Metal bindingi150 – 1501Iron (heme axial ligand) By similarity

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c homolog
Gene namesi
Name:cycM
Ordered Locus Names:RP253
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88Cytoplasmic Reviewed prediction
Transmembranei9 – 2921Helical; Signal-anchor; Reviewed prediction
Add
BLAST
Topological domaini30 – 175146Periplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 175175Cytochrome c homolog
PRO_0000288758Add
BLAST

Post-translational modificationi

Binds 1 heme group per subunit By similarity.

Interactioni

Protein-protein interaction databases

STRINGi272947.RP253.

Structurei

3D structure databases

ProteinModelPortaliQ9ZDS2.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3474.
HOGENOMiHOG000009763.
KOiK08738.
OMAiNYSKAML.
OrthoDBiEOG6MM1PX.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view]
PANTHERiPTHR11961. PTHR11961. 1 hit.
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00604. CYTCHRMECIAB.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZDS2-1 [UniParc]FASTAAdd to Basket

« Hide

MTGKELNKIV AAILFASLIA MIVGFIANIL YKPNLHVLHR GYSIAIQKSS    50
SNESATVIAQ ESVNIQELMK TANANHGREI AKKCLMCHSL DKDGPNKLGP 100
HLWNIVGRPK ASITDYKYSF AISKLGGVWD DENLFAFLHK PSSYAPGTKM 150
SFAGISKPQD IADVILFLKN YVHDQ 175
Length:175
Mass (Da):19,286
Last modified:May 1, 1999 - v1
Checksum:i5E3422344225017D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235271 Genomic DNA. Translation: CAA14715.1.
PIRiA71680.
RefSeqiNP_220638.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14715; CAA14715; CAA14715.
GeneIDi883146.
KEGGirpr:RP253.
PATRICi17901266. VBIRicPro72556_0260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235271 Genomic DNA. Translation: CAA14715.1 .
PIRi A71680.
RefSeqi NP_220638.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZDS2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272947.RP253.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA14715 ; CAA14715 ; CAA14715 .
GeneIDi 883146.
KEGGi rpr:RP253.
PATRICi 17901266. VBIRicPro72556_0260.

Phylogenomic databases

eggNOGi COG3474.
HOGENOMi HOG000009763.
KOi K08738.
OMAi NYSKAML.
OrthoDBi EOG6MM1PX.

Family and domain databases

Gene3Di 1.10.760.10. 1 hit.
InterProi IPR009056. Cyt_c-like_dom.
IPR002327. Cyt_c_1A/1B.
IPR003088. Cyt_c_dom.
[Graphical view ]
PANTHERi PTHR11961. PTHR11961. 1 hit.
Pfami PF00034. Cytochrom_C. 1 hit.
[Graphical view ]
PRINTSi PR00604. CYTCHRMECIAB.
SUPFAMi SSF46626. SSF46626. 1 hit.
PROSITEi PS51007. CYTC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiCYCM_RICPR
AccessioniPrimary (citable) accession number: Q9ZDS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi