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Q9ZDS2

- CYCM_RICPR

UniProt

Q9ZDS2 - CYCM_RICPR

Protein

Cytochrome c homolog

Gene

cycM

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    May be involved in electron transfer from bc1 complex to aa3.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei84 – 841Heme (covalent)PROSITE-ProRule annotation
    Binding sitei87 – 871Heme (covalent)PROSITE-ProRule annotation
    Metal bindingi88 – 881Iron (heme axial ligand)PROSITE-ProRule annotation
    Metal bindingi150 – 1501Iron (heme axial ligand)PROSITE-ProRule annotation

    GO - Molecular functioni

    1. electron carrier activity Source: InterPro
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. oxidation-reduction process Source: UniProtKB-KW

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c homolog
    Gene namesi
    Name:cycM
    Ordered Locus Names:RP253
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 175175Cytochrome c homologPRO_0000288758Add
    BLAST

    Post-translational modificationi

    Binds 1 heme group per subunit.By similarity

    Interactioni

    Protein-protein interaction databases

    STRINGi272947.RP253.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZDS2.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 88CytoplasmicSequence Analysis
    Topological domaini30 – 175146PeriplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei9 – 2921Helical; Signal-anchorSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3474.
    HOGENOMiHOG000009763.
    KOiK08738.
    OMAiNYSKAML.
    OrthoDBiEOG6MM1PX.

    Family and domain databases

    Gene3Di1.10.760.10. 1 hit.
    InterProiIPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view]
    PANTHERiPTHR11961. PTHR11961. 1 hit.
    PfamiPF00034. Cytochrom_C. 1 hit.
    [Graphical view]
    PRINTSiPR00604. CYTCHRMECIAB.
    SUPFAMiSSF46626. SSF46626. 1 hit.
    PROSITEiPS51007. CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZDS2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTGKELNKIV AAILFASLIA MIVGFIANIL YKPNLHVLHR GYSIAIQKSS    50
    SNESATVIAQ ESVNIQELMK TANANHGREI AKKCLMCHSL DKDGPNKLGP 100
    HLWNIVGRPK ASITDYKYSF AISKLGGVWD DENLFAFLHK PSSYAPGTKM 150
    SFAGISKPQD IADVILFLKN YVHDQ 175
    Length:175
    Mass (Da):19,286
    Last modified:May 1, 1999 - v1
    Checksum:i5E3422344225017D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235271 Genomic DNA. Translation: CAA14715.1.
    PIRiA71680.
    RefSeqiNP_220638.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA14715; CAA14715; CAA14715.
    GeneIDi883146.
    KEGGirpr:RP253.
    PATRICi17901266. VBIRicPro72556_0260.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235271 Genomic DNA. Translation: CAA14715.1 .
    PIRi A71680.
    RefSeqi NP_220638.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZDS2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP253.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA14715 ; CAA14715 ; CAA14715 .
    GeneIDi 883146.
    KEGGi rpr:RP253.
    PATRICi 17901266. VBIRicPro72556_0260.

    Phylogenomic databases

    eggNOGi COG3474.
    HOGENOMi HOG000009763.
    KOi K08738.
    OMAi NYSKAML.
    OrthoDBi EOG6MM1PX.

    Family and domain databases

    Gene3Di 1.10.760.10. 1 hit.
    InterProi IPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view ]
    PANTHERi PTHR11961. PTHR11961. 1 hit.
    Pfami PF00034. Cytochrom_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00604. CYTCHRMECIAB.
    SUPFAMi SSF46626. SSF46626. 1 hit.
    PROSITEi PS51007. CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiCYCM_RICPR
    AccessioniPrimary (citable) accession number: Q9ZDS2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3