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Q9ZDQ5 (UCRI_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquinol-cytochrome c reductase iron-sulfur subunit

EC=1.10.2.2
Alternative name(s):
Rieske iron-sulfur protein
Short name=RISP
Gene names
Name:petA
Ordered Locus Names:RP270
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.

Catalytic activity

Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+.

Cofactor

Binds 1 2Fe-2S cluster per subunit By similarity.

Subunit structure

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Miscellaneous

The Rieske protein is a high potential 2Fe-2S protein.

Sequence similarities

Contains 1 Rieske domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 177177Ubiquinol-cytochrome c reductase iron-sulfur subunit
PRO_0000127766

Regions

Transmembrane18 – 3821Helical; Potential
Domain88 – 17588Rieske

Sites

Metal binding1201Iron-sulfur (2Fe-2S) By similarity
Metal binding1221Iron-sulfur (2Fe-2S); via pros nitrogen By similarity
Metal binding1391Iron-sulfur (2Fe-2S) By similarity
Metal binding1421Iron-sulfur (2Fe-2S); via pros nitrogen By similarity

Amino acid modifications

Disulfide bond125 ↔ 141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZDQ5 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: D6DA19D703A90B39

FASTA17719,350
        10         20         30         40         50         60 
MSDTEDNKNK QTTRRDFIVL TASSVAAVGA ACAFWPIIDS FNPSADVLAL SSIEVDLSNI 

        70         80         90        100        110        120 
AIGQTVTVKW QGKPIFITNR THDEIAAARA VKMSELIDPE RDEVRVKAGH DNWLVTIGIC 

       130        140        150        160        170 
THLGCVPLSH KGEYNGWFCP CHGSQYDSSG RVRKGPAPLN LAVPPYIFIS DKKIRIG 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235271 Genomic DNA. Translation: CAA14732.1.
PIRB71682.
RefSeqNP_220655.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZDQ5.
SMRQ9ZDQ5. Positions 118-163.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP270.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA14732; CAA14732; CAA14732.
GeneID883187.
KEGGrpr:RP270.
PATRIC17901301. VBIRicPro72556_0277.

Phylogenomic databases

eggNOGCOG0723.
HOGENOMHOG000255193.
KOK00411.
OMAAVGLCTH.
OrthoDBEOG6RNQD9.
ProtClustDBCLSK870834.

Family and domain databases

Gene3D2.102.10.10. 1 hit.
InterProIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERPTHR10134. PTHR10134. 1 hit.
PfamPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSPR00162. RIESKE.
SUPFAMSSF50022. SSF50022. 1 hit.
TIGRFAMsTIGR01416. Rieske_proteo. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUCRI_RICPR
AccessionPrimary (citable) accession number: Q9ZDQ5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 1999
Last modified: April 16, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names