ID CYAY_RICPR Reviewed; 104 AA. AC Q9ZDK5; DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1999, sequence version 1. DT 27-MAR-2024, entry version 103. DE RecName: Full=Iron-sulfur cluster assembly protein CyaY {ECO:0000255|HAMAP-Rule:MF_00142}; GN Name=cyaY {ECO:0000255|HAMAP-Rule:MF_00142}; OrderedLocusNames=RP323; OS Rickettsia prowazekii (strain Madrid E). OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales; OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group. OX NCBI_TaxID=272947; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Madrid E; RX PubMed=9823893; DOI=10.1038/24094; RA Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., RA Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., RA Kurland C.G.; RT "The genome sequence of Rickettsia prowazekii and the origin of RT mitochondria."; RL Nature 396:133-140(1998). CC -!- FUNCTION: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a CC regulator of Fe-S biogenesis. {ECO:0000255|HAMAP-Rule:MF_00142}. CC -!- SIMILARITY: Belongs to the frataxin family. {ECO:0000255|HAMAP- CC Rule:MF_00142, ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ235271; CAA14783.1; -; Genomic_DNA. DR PIR; E71688; E71688. DR RefSeq; NP_220706.1; NC_000963.1. DR RefSeq; WP_004597434.1; NC_000963.1. DR AlphaFoldDB; Q9ZDK5; -. DR SMR; Q9ZDK5; -. DR STRING; 272947.gene:17555403; -. DR EnsemblBacteria; CAA14783; CAA14783; CAA14783. DR GeneID; 57569449; -. DR KEGG; rpr:RP323; -. DR PATRIC; fig|272947.5.peg.332; -. DR eggNOG; COG1965; Bacteria. DR HOGENOM; CLU_080880_4_1_5; -. DR OrthoDB; 8480400at2; -. DR Proteomes; UP000002480; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProt. DR GO; GO:0008199; F:ferric iron binding; IEA:InterPro. DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule. DR CDD; cd00503; Frataxin; 1. DR Gene3D; 3.30.920.10; Frataxin/CyaY; 1. DR HAMAP; MF_00142; CyaY; 1. DR InterPro; IPR047584; CyaY. DR InterPro; IPR002908; Frataxin/CyaY. DR InterPro; IPR036524; Frataxin/CyaY_sf. DR InterPro; IPR020895; Frataxin_CS. DR NCBIfam; TIGR03421; FeS_CyaY; 1. DR PANTHER; PTHR16821; FRATAXIN; 1. DR PANTHER; PTHR16821:SF2; FRATAXIN, MITOCHONDRIAL; 1. DR Pfam; PF01491; Frataxin_Cyay; 1. DR SMART; SM01219; Frataxin_Cyay; 1. DR SUPFAM; SSF55387; Frataxin/Nqo15-like; 1. DR PROSITE; PS01344; FRATAXIN_1; 1. DR PROSITE; PS50810; FRATAXIN_2; 1. PE 3: Inferred from homology; KW Iron; Metal-binding; Reference proteome. FT CHAIN 1..104 FT /note="Iron-sulfur cluster assembly protein CyaY" FT /id="PRO_0000193957" SQ SEQUENCE 104 AA; 11961 MW; CC3405C89CCB51A0 CRC64; MNNTAFSKLA ETTIVYIVDK IEEQDLEGII DVDLQGDILN LDTENGIYVI NTQSASKEIW LSSPVSGPHH FFYEQGKWKS RIGFELMVLL TEELGIRFDK YEIF //