Q9ZDI3 (RS4_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	RP345

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP-Rule MF_01306 With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01306
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	30S ribosomal protein S4 HAMAP-Rule MF_01306		PRO_0000132447
Regions
	Domain	94 – 157	64	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q9ZDI3 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 3750C8D28A9FAF49	FASTA	205	23,318
	10 20 30 40 50 60 MTKIVRSKYK ASRRLGVSLW GDSKDAFNTR NYRPGQHGQN TMIKTSDYGL HLKAKQRLKC 70 80 90 100 110 120 YYGRVTEKQF RNIFALAQRM KGNTGENFIG LLESRLDTVV YRMNIAPTIF AARQLVSHGH 130 140 150 160 170 180 IKLNGKKADI ASIRLKEGDI IEIKESIQQI PLIQESISKQ GQTTPGYLSF DIPSLTGKYL 190 200 RVPALSDVPY PFEAEVHLVI ELYSR

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235271 Genomic DNA. Translation: CAA14805.1.
PIR	C71691.
RefSeq	NP_220728.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZDI3.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP345.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA14805; CAA14805; CAA14805.
GeneID	883363.
KEGG	rpr:RP345.
PATRIC	17901459. VBIRicPro72556_0355.
Phylogenomic databases
eggNOG	COG0522.
HOGENOM	HOG000221004.
KO	K02986.
OMA	YRCKPGD.
ProtClustDB	PRK05327.
Family and domain databases
Gene3D	1.10.1050.10. 1 hit. 3.10.290.10. 1 hit.
HAMAP	MF_01306_B. Ribosomal_S4_B.
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
PANTHER	PTHR11831. PTHR11831. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. rpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_RICPR

Accession

Primary (citable) accession number: Q9ZDI3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program