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Q9ZD46

- TRUB_RICPR

UniProt

Q9ZD46 - TRUB_RICPR

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Protein
Putative tRNA pseudouridine synthase B
Gene
truB, RP501
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5 - Protein uncertaini

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity.

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Nucleophile By similarity

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. pseudouridine synthase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tRNA pseudouridine synthase B (EC:5.4.99.25)
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name:
Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truB
Ordered Locus Names:RP501
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172Putative tRNA pseudouridine synthase B
PRO_0000121895Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP501.

Structurei

3D structure databases

ProteinModelPortaliQ9ZD46.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0130.
KOiK03177.
OMAiLEGHIFL.
OrthoDBiEOG6358D3.

Family and domain databases

InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZD46-1 [UniParc]FASTAAdd to Basket

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MGNYWLNFYK PRGISSAKLV NIVKKIIGKT KIGHAGTLDV EAEGILPLAV    50
GEATKLIQLL IDARKTYIFS VKFGTQTDSG DYTGKVIASK DYIPSQEEVY 100
TVCSKFIGNI RQVPPIFSAI KVNGVRAYKL AREGKIVELK PRNITIYDLK 150
CLNFDKENAI ATYYTECSKG LI 172
Length:172
Mass (Da):19,116
Last modified:May 1, 1999 - v1
Checksum:i66B2F753BDA8566C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA14953.1.
PIRiG71653.
RefSeqiNP_220877.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14953; CAA14953; CAA14953.
GeneIDi883154.
KEGGirpr:RP501.
PATRICi17901784. VBIRicPro72556_0510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA14953.1 .
PIRi G71653.
RefSeqi NP_220877.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZD46.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272947.RP501.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA14953 ; CAA14953 ; CAA14953 .
GeneIDi 883154.
KEGGi rpr:RP501.
PATRICi 17901784. VBIRicPro72556_0510.

Phylogenomic databases

eggNOGi COG0130.
KOi K03177.
OMAi LEGHIFL.
OrthoDBi EOG6358D3.

Family and domain databases

InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiTRUB_RICPR
AccessioniPrimary (citable) accession number: Q9ZD46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. C-terminally truncated compared to other bacterial TruB.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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