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Q9ZD46

- TRUB_RICPR

UniProt

Q9ZD46 - TRUB_RICPR

Protein

Putative tRNA pseudouridine synthase B

Gene

truB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5- Protein uncertaini
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    • Comment

    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.By similarity

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei39 – 391NucleophileBy similarity

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: InterPro
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. pseudouridine synthesis Source: InterPro
    2. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tRNA pseudouridine synthase B (EC:5.4.99.25)
    Alternative name(s):
    tRNA pseudouridine(55) synthase
    Short name:
    Psi55 synthase
    tRNA pseudouridylate synthase
    tRNA-uridine isomerase
    Gene namesi
    Name:truB
    Ordered Locus Names:RP501
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 172172Putative tRNA pseudouridine synthase BPRO_0000121895Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272947.RP501.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZD46.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0130.
    KOiK03177.
    OMAiLEGHIFL.
    OrthoDBiEOG6358D3.

    Family and domain databases

    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9ZD46-1 [UniParc]FASTAAdd to Basket

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    MGNYWLNFYK PRGISSAKLV NIVKKIIGKT KIGHAGTLDV EAEGILPLAV    50
    GEATKLIQLL IDARKTYIFS VKFGTQTDSG DYTGKVIASK DYIPSQEEVY 100
    TVCSKFIGNI RQVPPIFSAI KVNGVRAYKL AREGKIVELK PRNITIYDLK 150
    CLNFDKENAI ATYYTECSKG LI 172
    Length:172
    Mass (Da):19,116
    Last modified:May 1, 1999 - v1
    Checksum:i66B2F753BDA8566C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA14953.1.
    PIRiG71653.
    RefSeqiNP_220877.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA14953; CAA14953; CAA14953.
    GeneIDi883154.
    KEGGirpr:RP501.
    PATRICi17901784. VBIRicPro72556_0510.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA14953.1 .
    PIRi G71653.
    RefSeqi NP_220877.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZD46.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP501.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA14953 ; CAA14953 ; CAA14953 .
    GeneIDi 883154.
    KEGGi rpr:RP501.
    PATRICi 17901784. VBIRicPro72556_0510.

    Phylogenomic databases

    eggNOGi COG0130.
    KOi K03177.
    OMAi LEGHIFL.
    OrthoDBi EOG6358D3.

    Family and domain databases

    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiTRUB_RICPR
    AccessioniPrimary (citable) accession number: Q9ZD46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 4, 2001
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Could be the product of a pseudogene. C-terminally truncated compared to other bacterial TruB.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3