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Protein

Putative tRNA pseudouridine synthase B

Gene

truB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.By similarity

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei39NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciRPRO272947:G1GT0-503-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tRNA pseudouridine synthase B (EC:5.4.99.25)
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name:
Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truB
Ordered Locus Names:RP501
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001218951 – 172Putative tRNA pseudouridine synthase BAdd BLAST172

Interactioni

Protein-protein interaction databases

STRINGi272947.RP501.

Structurei

3D structure databases

ProteinModelPortaliQ9ZD46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
KOiK03177.
OMAiPLCFNEA.

Family and domain databases

InterProiView protein in InterPro
IPR020103. PsdUridine_synth_cat_dom_sf.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiView protein in Pfam
PF01509. TruB_N. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZD46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNYWLNFYK PRGISSAKLV NIVKKIIGKT KIGHAGTLDV EAEGILPLAV
60 70 80 90 100
GEATKLIQLL IDARKTYIFS VKFGTQTDSG DYTGKVIASK DYIPSQEEVY
110 120 130 140 150
TVCSKFIGNI RQVPPIFSAI KVNGVRAYKL AREGKIVELK PRNITIYDLK
160 170
CLNFDKENAI ATYYTECSKG LI
Length:172
Mass (Da):19,116
Last modified:May 1, 1999 - v1
Checksum:i66B2F753BDA8566C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA14953.1.
PIRiG71653.
RefSeqiNP_220877.1. NC_000963.1.
WP_010886307.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA14953; CAA14953; CAA14953.
GeneIDi883154.
KEGGirpr:RP501.
PATRICifig|272947.5.peg.510.

Entry informationi

Entry nameiTRUB_RICPR
AccessioniPrimary (citable) accession number: Q9ZD46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. C-terminally truncated compared to other bacterial TruB.Curated

Keywords - Technical termi

Complete proteome, Reference proteome