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Q9ZD34 (Q9ZD34_RICPR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Ordered Locus Names:RP513
OrganismRickettsia prowazekii (strain Madrid E)
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length607 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Sequences

Sequence LengthMass (Da)Tools
Q9ZD34 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: B438BFB3C066B553

FASTA60768,733
        10         20         30         40         50         60 
MNTLKKNKFQ ITINNKYNNL LTPFGKAILR DRYLMKGEDF QDLFARVSSH YAENKQHAQK 

        70         80         90        100        110        120 
LYEYMSQMWF MPATPILSNG GTERGLPISC FLNETDDSLD DIVNLWMENV WLAARGGGIG 

       130        140        150        160        170        180 
SYWGNVRSIN EAIRDKGHSS GIIPFIKVMD SMTLAISQGS IRRGSSAVYL PINHPEIEEF 

       190        200        210        220        230        240 
IDIRRPTGGD VNRKSLNIHH GITITDEFMQ AVENNMDFDL VSPATKKVAN KVRARDLWIK 

       250        260        270        280        290        300 
LLTTRIETGE PYLLFIDSVN KTIPEHHKKL GLQVKMSNLC SEITLPTGID HLGNSRTAVC 

       310        320        330        340        350        360 
CLASLNLEYY EVWKDDKEFI HSIMLFLDNV LEDFINKAPN TMARAKYAAF RERSVGLGVI 

       370        380        390        400        410        420 
GFHSFLQMKK IPIESVMAKV WNKKIFEYIS AEVDKASIEI GKDKGACPDA LDSGSNERFS 

       430        440        450        460        470        480 
NKTAIAPTAS ISVIAGNASP GIEPFAANSF VQKTLTGSFN VRNKHLEQLL EEKGFNNDQV 

       490        500        510        520        530        540 
WSSIATHEGS VQHLTFLSEE EKQIFKTAYE IDQNWLIELA ADRTPYITQS QALNIFLHGN 

       550        560        570        580        590        600 
VSKKYLNNIH FKAWKKGIKS LYYCRSTSIQ RADKVSHDVL KADFKDLEKQ NDKLAQTRNY 


EECLACQ

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References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed: 9823893] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ235272 Genomic DNA. Translation: CAA14965.1.
PIRC71655.
RefSeqNP_220889.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZD34.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID883164.
GenomeReviewsGene locus RP513 in contig AJ235269_GR.
KEGGrpr:RP513.
PATRIC17901810. VBIRicPro72556_0523.

Phylogenomic databases

HOGENOMHBG296647.
OMAYVRIRQD.
ProtClustDBPRK09102.

Enzyme and pathway databases

BioCycRPRO272947:RP513-MONOMER.

Family and domain databases

InterProIPR013509. Ribncl_Rdtase_lsu_N.
IPR000788. Ribncl_red_lg_C.
IPR008926. Ribnucl_Rdtase_R1-su_N.
[Graphical view]
KOK00525.
PfamPF02867. Ribonuc_red_lgC. 2 hits.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ9ZD34_RICPR
AccessionPrimary (citable) accession number: Q9ZD34
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info