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Protein

Putative response regulator NtrX-like

Gene

RP562

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system RP562/RP614.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi171 – 1788ATPPROSITE-ProRule annotation
Nucleotide bindingi232 – 24110ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative response regulator NtrX-like
Gene namesi
Ordered Locus Names:RP562
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Putative response regulator NtrX-likePRO_0000282384Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei54 – 5414-aspartylphosphatePROSITE-ProRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi272947.RP562.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 121117Response regulatoryPROSITE-ProRule annotationAdd
BLAST
Domaini143 – 369227Sigma-54 factor interactionPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 response regulatory domain.PROSITE-ProRule annotation
Contains 1 sigma-54 factor interaction domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2204.
HOGENOMiHOG000058489.
KOiK13599.
OMAiARWLHEK.
OrthoDBiEOG6WHNMG.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR002078. Sigma_54_int.
IPR025944. Sigma_54_int_dom_CS.
[Graphical view]
PfamiPF02954. HTH_8. 1 hit.
PF00072. Response_reg. 1 hit.
PF00158. Sigma54_activat. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZCY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLDVLIVD DEESIRNLIA ANLKDEGFNP KIAANSTQAL KIISEKPVSA
60 70 80 90 100
VILDIWLQGS EIDGLGVLEI IKKRYPLMPV IIISGHGTIE TAVNAIKMGA
110 120 130 140 150
YDYIEKPFNN DKLIILLKRA CEVTKLKREN IDLKSKVIDK TELVGGCPVT
160 170 180 190 200
LKYKMEIEKA ASSSSRIMIH GKVGSGKELA ARLIHKQSKR VNNPFIIFSP
210 220 230 240 250
TCMTTEKINQ ELFGESEKQE NNNKRPTILE FANNGTLYID EISNIPIPIQ
260 270 280 290 300
VKLLKFLKDQ TITKPCGKKT KVDIKIITST AKNIQDEVNN GKFLEDLYYR
310 320 330 340 350
LNVFSLKVPS LYERKEDIPL LVKYFVKQLS KFSGLKERHF SDEAIAALQS
360 370 380 390 400
YEWPGNIRQL RNVVEWTLIM NPLTTGNNEI IKPYMIPSEI LANSANLTKL
410 420 430 440 450
EDSFDMLSMP LREAREVFER QYLSAQMSRF NNNISKTSSF VGMERSALHR
460 470
KLKLLSLHIP PTNRINEEEY EKANA
Length:475
Mass (Da):53,918
Last modified:May 1, 1999 - v1
Checksum:iFE22277175CE5D05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA15010.1.
PIRiH71660.
RefSeqiNP_220934.1. NC_000963.1.
WP_004599035.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15010; CAA15010; CAA15010.
GeneIDi883256.
KEGGirpr:RP562.
PATRICi17901929. VBIRicPro72556_0578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA15010.1.
PIRiH71660.
RefSeqiNP_220934.1. NC_000963.1.
WP_004599035.1. NC_000963.1.

3D structure databases

ProteinModelPortaliQ9ZCY9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP562.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA15010; CAA15010; CAA15010.
GeneIDi883256.
KEGGirpr:RP562.
PATRICi17901929. VBIRicPro72556_0578.

Phylogenomic databases

eggNOGiCOG2204.
HOGENOMiHOG000058489.
KOiK13599.
OMAiARWLHEK.
OrthoDBiEOG6WHNMG.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011006. CheY-like_superfamily.
IPR009057. Homeodomain-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR002078. Sigma_54_int.
IPR025944. Sigma_54_int_dom_CS.
[Graphical view]
PfamiPF02954. HTH_8. 1 hit.
PF00072. Response_reg. 1 hit.
PF00158. Sigma54_activat. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiNTRXL_RICPR
AccessioniPrimary (citable) accession number: Q9ZCY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: May 1, 1999
Last modified: June 24, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.