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Q9ZCX4

- RPOZ_RICPR

UniProt

Q9ZCX4 - RPOZ_RICPR

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Protein
DNA-directed RNA polymerase subunit omega
Gene
rpoZ, RP578
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit omega (EC:2.7.7.6)
Short name:
RNAP omega subunit
Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega
Gene namesi
Name:rpoZ
Ordered Locus Names:RP578
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 127127DNA-directed RNA polymerase subunit omegaUniRule annotation
PRO_0000128971Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Protein-protein interaction databases

STRINGi272947.RP578.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCX4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1758.
HOGENOMiHOG000245721.
KOiK03060.
OMAiCITEDYS.
OrthoDBiEOG6Q5NV5.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZCX4-1 [UniParc]FASTAAdd to Basket

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MARITAEDCN KIIPDRFRLV VLATRYAKLL NYKVETNQIK KEKRDKPPVI    50
SLRRIAAGKV SVPQLEQDLI NSLRTRMMIE PLINQDESED VEEKFEYLPE 100
VYIGEDYSDL DDQIFINENG EDYETDK 127
Length:127
Mass (Da):14,897
Last modified:May 1, 1999 - v1
Checksum:i3FCF0CFDF61A53FE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15025.1.
PIRiG71662.
RefSeqiNP_220949.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15025; CAA15025; CAA15025.
GeneIDi883937.
KEGGirpr:RP578.
PATRICi17901965. VBIRicPro72556_0595.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15025.1 .
PIRi G71662.
RefSeqi NP_220949.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZCX4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272947.RP578.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA15025 ; CAA15025 ; CAA15025 .
GeneIDi 883937.
KEGGi rpr:RP578.
PATRICi 17901965. VBIRicPro72556_0595.

Phylogenomic databases

eggNOGi COG1758.
HOGENOMi HOG000245721.
KOi K03060.
OMAi CITEDYS.
OrthoDBi EOG6Q5NV5.

Family and domain databases

Gene3Di 3.90.940.10. 1 hit.
HAMAPi MF_00366. RNApol_bact_RpoZ.
InterProi IPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view ]
Pfami PF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view ]
SUPFAMi SSF63562. SSF63562. 1 hit.
TIGRFAMsi TIGR00690. rpoZ. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiRPOZ_RICPR
AccessioniPrimary (citable) accession number: Q9ZCX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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