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Q9ZCX4 (RPOZ_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit omega

Short name=RNAP omega subunit
EC=2.7.7.6
Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega
Gene names
Name:rpoZ
Ordered Locus Names:RP578
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP-Rule MF_00366

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00366

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 127127DNA-directed RNA polymerase subunit omega HAMAP-Rule MF_00366
PRO_0000128971

Sequences

Sequence LengthMass (Da)Tools
Q9ZCX4 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 3FCF0CFDF61A53FE

FASTA12714,897
        10         20         30         40         50         60 
MARITAEDCN KIIPDRFRLV VLATRYAKLL NYKVETNQIK KEKRDKPPVI SLRRIAAGKV 

        70         80         90        100        110        120 
SVPQLEQDLI NSLRTRMMIE PLINQDESED VEEKFEYLPE VYIGEDYSDL DDQIFINENG 


EDYETDK 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235272 Genomic DNA. Translation: CAA15025.1.
PIRG71662.
RefSeqNP_220949.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZCX4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP578.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15025; CAA15025; CAA15025.
GeneID883937.
KEGGrpr:RP578.
PATRIC17901965. VBIRicPro72556_0595.

Phylogenomic databases

eggNOGCOG1758.
HOGENOMHOG000245721.
KOK03060.
OMACITEDYS.
OrthoDBEOG6Q5NV5.
ProtClustDBPRK00392.

Family and domain databases

Gene3D3.90.940.10. 1 hit.
HAMAPMF_00366. RNApol_bact_RpoZ.
InterProIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMSSF63562. SSF63562. 1 hit.
TIGRFAMsTIGR00690. rpoZ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOZ_RICPR
AccessionPrimary (citable) accession number: Q9ZCX4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names