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Q9ZCX4

- RPOZ_RICPR

UniProt

Q9ZCX4 - RPOZ_RICPR

Protein

DNA-directed RNA polymerase subunit omega

Gene

rpoZ

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity.By similarity

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Transcription

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymerase subunit omega (EC:2.7.7.6)
    Short name:
    RNAP omega subunit
    Alternative name(s):
    RNA polymerase omega subunit
    Transcriptase subunit omega
    Gene namesi
    Name:rpoZ
    Ordered Locus Names:RP578
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymerase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 127127DNA-directed RNA polymerase subunit omegaPRO_0000128971Add
    BLAST

    Interactioni

    Subunit structurei

    The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.By similarity

    Protein-protein interaction databases

    STRINGi272947.RP578.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZCX4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1758.
    HOGENOMiHOG000245721.
    KOiK03060.
    OMAiCITEDYS.
    OrthoDBiEOG6Q5NV5.

    Family and domain databases

    Gene3Di3.90.940.10. 1 hit.
    HAMAPiMF_00366. RNApol_bact_RpoZ.
    InterProiIPR003716. DNA-dir_RNA_pol_omega.
    IPR006110. Pol_omega/K/RPB6.
    IPR012293. RNAP_RPB6_omega.
    [Graphical view]
    PfamiPF01192. RNA_pol_Rpb6. 1 hit.
    [Graphical view]
    SUPFAMiSSF63562. SSF63562. 1 hit.
    TIGRFAMsiTIGR00690. rpoZ. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9ZCX4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARITAEDCN KIIPDRFRLV VLATRYAKLL NYKVETNQIK KEKRDKPPVI    50
    SLRRIAAGKV SVPQLEQDLI NSLRTRMMIE PLINQDESED VEEKFEYLPE 100
    VYIGEDYSDL DDQIFINENG EDYETDK 127
    Length:127
    Mass (Da):14,897
    Last modified:May 1, 1999 - v1
    Checksum:i3FCF0CFDF61A53FE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15025.1.
    PIRiG71662.
    RefSeqiNP_220949.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA15025; CAA15025; CAA15025.
    GeneIDi883937.
    KEGGirpr:RP578.
    PATRICi17901965. VBIRicPro72556_0595.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15025.1 .
    PIRi G71662.
    RefSeqi NP_220949.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZCX4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP578.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA15025 ; CAA15025 ; CAA15025 .
    GeneIDi 883937.
    KEGGi rpr:RP578.
    PATRICi 17901965. VBIRicPro72556_0595.

    Phylogenomic databases

    eggNOGi COG1758.
    HOGENOMi HOG000245721.
    KOi K03060.
    OMAi CITEDYS.
    OrthoDBi EOG6Q5NV5.

    Family and domain databases

    Gene3Di 3.90.940.10. 1 hit.
    HAMAPi MF_00366. RNApol_bact_RpoZ.
    InterProi IPR003716. DNA-dir_RNA_pol_omega.
    IPR006110. Pol_omega/K/RPB6.
    IPR012293. RNAP_RPB6_omega.
    [Graphical view ]
    Pfami PF01192. RNA_pol_Rpb6. 1 hit.
    [Graphical view ]
    SUPFAMi SSF63562. SSF63562. 1 hit.
    TIGRFAMsi TIGR00690. rpoZ. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiRPOZ_RICPR
    AccessioniPrimary (citable) accession number: Q9ZCX4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3