Q9ZCX4 (RPOZ_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Ordered Locus Names:	RP578

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP-Rule MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP
Cellular_component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 127	127	DNA-directed RNA polymerase subunit omega HAMAP-Rule MF_00366		PRO_0000128971

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCX4 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 3FCF0CFDF61A53FE	FASTA	127	14,897
	10 20 30 40 50 60 MARITAEDCN KIIPDRFRLV VLATRYAKLL NYKVETNQIK KEKRDKPPVI SLRRIAAGKV 70 80 90 100 110 120 SVPQLEQDLI NSLRTRMMIE PLINQDESED VEEKFEYLPE VYIGEDYSDL DDQIFINENG EDYETDK

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235272 Genomic DNA. Translation: CAA15025.1.
PIR	G71662.
RefSeq	NP_220949.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZCX4.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP578.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA15025; CAA15025; CAA15025.
GeneID	883937.
KEGG	rpr:RP578.
PATRIC	17901965. VBIRicPro72556_0595.
Phylogenomic databases
eggNOG	COG1758.
HOGENOM	HOG000245721.
KO	K03060.
OMA	NQDESED.
ProtClustDB	PRK00392.
Family and domain databases
Gene3D	3.90.940.10. 1 hit.
HAMAP	MF_00366. RNApol_bact_RpoZ.
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. rpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_RICPR

Accession

Primary (citable) accession number: Q9ZCX4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program