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Protein

Sec translocon accessory complex subunit YajC

Gene

yajC

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.By similarity

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec translocon accessory complex subunit YajC
Gene namesi
Name:yajC
Ordered Locus Names:RP585
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane By similarity; Single-pass membrane protein By similarity

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000970341 – 142Sec translocon accessory complex subunit YajCAdd BLAST142

Interactioni

Subunit structurei

Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).By similarity

Protein-protein interaction databases

STRINGi272947.RP585.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCW9.
SMRiQ9ZCW9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YajC family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105VIE. Bacteria.
COG1862. LUCA.
HOGENOMiHOG000018859.
KOiK03210.
OMAiHMSANTQ.

Family and domain databases

InterProiView protein in InterPro
IPR003849. Preprotein_translocase_YajC.
PANTHERiPTHR33909:SF2. PTHR33909:SF2. 1 hit.
PfamiView protein in Pfam
PF02699. YajC. 1 hit.
PRINTSiPR01853. YAJCTRNLCASE.
SMARTiView protein in SMART
SM01323. YajC. 1 hit.
TIGRFAMsiTIGR00739. yajC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZCW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQHTQDNQI NNNETIEIQE TDTVPVETNS LQSGLTSLIP MILIFAVFYF
60 70 80 90 100
LLLRPQEKRR KEREKLVSGV KKGEEVLINS GIYGIVTKVS ENDNNIEIEI
110 120 130 140
AKDVRIKAIK SAIVDITSRK REVAATQENN KKNKKVSCAK SS
Length:142
Mass (Da):16,001
Last modified:May 1, 1999 - v1
Checksum:iF84B8586B54D7105
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA15030.1.
PIRiD71663.
RefSeqiNP_220954.1. NC_000963.1.
WP_004597903.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15030; CAA15030; CAA15030.
GeneIDi883835.
KEGGirpr:RP585.
PATRICifig|272947.5.peg.601.

Similar proteinsi

Entry informationi

Entry nameiYAJC_RICPR
AccessioniPrimary (citable) accession number: Q9ZCW9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: August 30, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families