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Q9ZCW8 (SECD_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein translocase subunit SecD
Gene names
Name:secD
Ordered Locus Names:RP586
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length518 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity. HAMAP-Rule MF_01463

Subunit structure

Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01463.

Sequence similarities

Belongs to the SecD/SecF family. SecD subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 518518Protein translocase subunit SecD HAMAP-Rule MF_01463
PRO_0000095968

Regions

Transmembrane9 – 2921Helical; Potential
Transmembrane356 – 37621Helical; Potential
Transmembrane377 – 39721Helical; Potential
Transmembrane406 – 42621Helical; Potential
Transmembrane463 – 48321Helical; Potential
Transmembrane486 – 50621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9ZCW8 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 86D6FC2A5B5DE2AA

FASTA51856,712
        10         20         30         40         50         60 
MQNLPKWKIV LSIICTVFAI ICALPNFIQI NSKFLPHDSI NLGLDLRGGA NLLLDVDFDT 

        70         80         90        100        110        120 
YLNDSMENLA DTLRKNLRKH KIGYKNLLVR HNNIQLEVRS PEVLKSLKKI INKIDPEIII 

       130        140        150        160        170        180 
GVNKNKIKLR YSESRFNDLL NKVVEQSIEI VRMRVDSTGT KEPTLQRQGN KHILLQVPGS 

       190        200        210        220        230        240 
ENPSYLKNIL GKTAKLTFHL VDENANIEDA IKGHVPLGSM LIKGDSKHHG EYYIVIKKKV 

       250        260        270        280        290        300 
LLSGAHLTKA SASFDQNSQP IVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPII 

       310        320        330        340        350        360 
NGAIIGGNGI ITGNFTIESA NELALLLRVG SLPTPLKIIE ERSIGPNLGA DSIESGKKAG 

       370        380        390        400        410        420 
LIGFVAVCIF MILSYGVIGL FANIALILAL LYILALLSLF QATLTLPGIA GIILTIGMAV 

       430        440        450        460        470        480 
DANVLIYERI KEELHKGVSN LYAIRTGFES AFATIIDSNI TTLIVAFALY IFGVGAIKGF 

       490        500        510 
AVALTIGIIS SMFSAIIITK LLIDVWVKYF KPKKLGLL 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235272 Genomic DNA. Translation: CAA15031.1.
PIRE71663.
RefSeqNP_220955.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZCW8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP586.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15031; CAA15031; CAA15031.
GeneID883986.
KEGGrpr:RP586.
PATRIC17901983. VBIRicPro72556_0602.

Phylogenomic databases

eggNOGCOG0342.
HOGENOMHOG000018636.
KOK03072.
OMAMATVFIE.
OrthoDBEOG6N0HJT.

Family and domain databases

HAMAPMF_01463_B. SecD_B.
InterProIPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view]
PfamPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSECD_RICPR
AccessionPrimary (citable) accession number: Q9ZCW8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names