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Protein

Protein translocase subunit SecD

Gene

secD

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecDUniRule annotation
Gene namesi
Name:secDUniRule annotation
Ordered Locus Names:RP586
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalUniRule annotationAdd
BLAST
Transmembranei356 – 37621HelicalUniRule annotationAdd
BLAST
Transmembranei377 – 39721HelicalUniRule annotationAdd
BLAST
Transmembranei406 – 42621HelicalUniRule annotationAdd
BLAST
Transmembranei463 – 48321HelicalUniRule annotationAdd
BLAST
Transmembranei486 – 50621HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 518518Protein translocase subunit SecDPRO_0000095968Add
BLAST

Interactioni

Subunit structurei

Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

Protein-protein interaction databases

STRINGi272947.RP586.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecD subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0342.
HOGENOMiHOG000018636.
KOiK03072.
OMAiAAPMEII.
OrthoDBiEOG6N0HJT.

Family and domain databases

HAMAPiMF_01463_B. SecD_B.
InterProiIPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZCW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNLPKWKIV LSIICTVFAI ICALPNFIQI NSKFLPHDSI NLGLDLRGGA
60 70 80 90 100
NLLLDVDFDT YLNDSMENLA DTLRKNLRKH KIGYKNLLVR HNNIQLEVRS
110 120 130 140 150
PEVLKSLKKI INKIDPEIII GVNKNKIKLR YSESRFNDLL NKVVEQSIEI
160 170 180 190 200
VRMRVDSTGT KEPTLQRQGN KHILLQVPGS ENPSYLKNIL GKTAKLTFHL
210 220 230 240 250
VDENANIEDA IKGHVPLGSM LIKGDSKHHG EYYIVIKKKV LLSGAHLTKA
260 270 280 290 300
SASFDQNSQP IVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPII
310 320 330 340 350
NGAIIGGNGI ITGNFTIESA NELALLLRVG SLPTPLKIIE ERSIGPNLGA
360 370 380 390 400
DSIESGKKAG LIGFVAVCIF MILSYGVIGL FANIALILAL LYILALLSLF
410 420 430 440 450
QATLTLPGIA GIILTIGMAV DANVLIYERI KEELHKGVSN LYAIRTGFES
460 470 480 490 500
AFATIIDSNI TTLIVAFALY IFGVGAIKGF AVALTIGIIS SMFSAIIITK
510
LLIDVWVKYF KPKKLGLL
Length:518
Mass (Da):56,712
Last modified:May 1, 1999 - v1
Checksum:i86D6FC2A5B5DE2AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA15031.1.
PIRiE71663.
RefSeqiNP_220955.1. NC_000963.1.
WP_004597905.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15031; CAA15031; CAA15031.
GeneIDi883986.
KEGGirpr:RP586.
PATRICi17901983. VBIRicPro72556_0602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235272 Genomic DNA. Translation: CAA15031.1.
PIRiE71663.
RefSeqiNP_220955.1. NC_000963.1.
WP_004597905.1. NC_000963.1.

3D structure databases

ProteinModelPortaliQ9ZCW8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP586.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA15031; CAA15031; CAA15031.
GeneIDi883986.
KEGGirpr:RP586.
PATRICi17901983. VBIRicPro72556_0602.

Phylogenomic databases

eggNOGiCOG0342.
HOGENOMiHOG000018636.
KOiK03072.
OMAiAAPMEII.
OrthoDBiEOG6N0HJT.

Family and domain databases

HAMAPiMF_01463_B. SecD_B.
InterProiIPR005791. SecD.
IPR022813. SecD/SecF_arch_bac.
IPR022645. SecD/SecF_bac.
IPR022646. SecD/SecF_CS.
[Graphical view]
PfamiPF07549. Sec_GG. 1 hit.
PF02355. SecD_SecF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
TIGR01129. secD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiSECD_RICPR
AccessioniPrimary (citable) accession number: Q9ZCW8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 27, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.