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Q9ZCW8

- SECD_RICPR

UniProt

Q9ZCW8 - SECD_RICPR

Protein

Protein translocase subunit SecD

Gene

secD

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation

    GO - Molecular functioni

    1. P-P-bond-hydrolysis-driven protein transmembrane transporter activity Source: InterPro

    GO - Biological processi

    1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
    2. protein targeting Source: UniProtKB-HAMAP
    3. protein transport by the Sec complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein translocase subunit SecDUniRule annotation
    Gene namesi
    Name:secDUniRule annotation
    Ordered Locus Names:RP586
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. intracellular Source: GOC
    3. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 518518Protein translocase subunit SecDPRO_0000095968Add
    BLAST

    Interactioni

    Subunit structurei

    Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

    Protein-protein interaction databases

    STRINGi272947.RP586.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZCW8.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei9 – 2921HelicalUniRule annotationAdd
    BLAST
    Transmembranei356 – 37621HelicalUniRule annotationAdd
    BLAST
    Transmembranei377 – 39721HelicalUniRule annotationAdd
    BLAST
    Transmembranei406 – 42621HelicalUniRule annotationAdd
    BLAST
    Transmembranei463 – 48321HelicalUniRule annotationAdd
    BLAST
    Transmembranei486 – 50621HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SecD/SecF family. SecD subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0342.
    HOGENOMiHOG000018636.
    KOiK03072.
    OMAiMATVFIE.
    OrthoDBiEOG6N0HJT.

    Family and domain databases

    HAMAPiMF_01463_B. SecD_B.
    InterProiIPR005791. SecD.
    IPR022813. SecD/SecF_arch_bac.
    IPR022645. SecD/SecF_bac.
    IPR022646. SecD/SecF_CS.
    [Graphical view]
    PfamiPF07549. Sec_GG. 1 hit.
    PF02355. SecD_SecF. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00916. 2A0604s01. 1 hit.
    TIGR01129. secD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9ZCW8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQNLPKWKIV LSIICTVFAI ICALPNFIQI NSKFLPHDSI NLGLDLRGGA    50
    NLLLDVDFDT YLNDSMENLA DTLRKNLRKH KIGYKNLLVR HNNIQLEVRS 100
    PEVLKSLKKI INKIDPEIII GVNKNKIKLR YSESRFNDLL NKVVEQSIEI 150
    VRMRVDSTGT KEPTLQRQGN KHILLQVPGS ENPSYLKNIL GKTAKLTFHL 200
    VDENANIEDA IKGHVPLGSM LIKGDSKHHG EYYIVIKKKV LLSGAHLTKA 250
    SASFDQNSQP IVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPII 300
    NGAIIGGNGI ITGNFTIESA NELALLLRVG SLPTPLKIIE ERSIGPNLGA 350
    DSIESGKKAG LIGFVAVCIF MILSYGVIGL FANIALILAL LYILALLSLF 400
    QATLTLPGIA GIILTIGMAV DANVLIYERI KEELHKGVSN LYAIRTGFES 450
    AFATIIDSNI TTLIVAFALY IFGVGAIKGF AVALTIGIIS SMFSAIIITK 500
    LLIDVWVKYF KPKKLGLL 518
    Length:518
    Mass (Da):56,712
    Last modified:May 1, 1999 - v1
    Checksum:i86D6FC2A5B5DE2AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15031.1.
    PIRiE71663.
    RefSeqiNP_220955.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA15031; CAA15031; CAA15031.
    GeneIDi883986.
    KEGGirpr:RP586.
    PATRICi17901983. VBIRicPro72556_0602.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15031.1 .
    PIRi E71663.
    RefSeqi NP_220955.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZCW8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272947.RP586.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA15031 ; CAA15031 ; CAA15031 .
    GeneIDi 883986.
    KEGGi rpr:RP586.
    PATRICi 17901983. VBIRicPro72556_0602.

    Phylogenomic databases

    eggNOGi COG0342.
    HOGENOMi HOG000018636.
    KOi K03072.
    OMAi MATVFIE.
    OrthoDBi EOG6N0HJT.

    Family and domain databases

    HAMAPi MF_01463_B. SecD_B.
    InterProi IPR005791. SecD.
    IPR022813. SecD/SecF_arch_bac.
    IPR022645. SecD/SecF_bac.
    IPR022646. SecD/SecF_CS.
    [Graphical view ]
    Pfami PF07549. Sec_GG. 1 hit.
    PF02355. SecD_SecF. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00916. 2A0604s01. 1 hit.
    TIGR01129. secD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiSECD_RICPR
    AccessioniPrimary (citable) accession number: Q9ZCW8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3