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Q9ZCV4

- PTH_RICPR

UniProt

Q9ZCV4 - PTH_RICPR

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Protein
Peptidyl-tRNA hydrolase
Gene
pth, RP605
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-tRNA hydrolase (EC:3.1.1.29)
    Short name:
    PTH
    Gene namesi
    Name:pth
    Ordered Locus Names:RP605
    OrganismiRickettsia prowazekii (strain Madrid E)
    Taxonomic identifieri272947 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000002480: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 185185Peptidyl-tRNA hydrolaseUniRule annotation
    PRO_0000187805Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Protein-protein interaction databases

    STRINGi272947.RP605.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZCV4.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PTH family.

    Phylogenomic databases

    eggNOGiCOG0193.
    HOGENOMiHOG000004797.
    KOiK01056.
    OMAiAMHRLHS.
    OrthoDBiEOG6C5RTR.

    Family and domain databases

    Gene3Di3.40.50.1470. 1 hit.
    HAMAPiMF_00083. Pept_tRNA_hydro_bact.
    InterProiIPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view]
    PANTHERiPTHR17224. PTHR17224. 1 hit.
    PfamiPF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view]
    SUPFAMiSSF53178. SSF53178. 1 hit.
    TIGRFAMsiTIGR00447. pth. 1 hit.
    PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZCV4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MILVIGLGNP GTEYQYTRHN IGFIAIERIA SKYHLSFSIK KKFNCEIAEA    50
    VIDRQKIIFI KPTTYMNLSG KSVILVKTYY NIKYEKVFVI HDDIDLEIGR 100
    IKFKTGGGNG GHNGLKSIDV VIGNHYNRIR IGIGRPKNNH DVADYVLNNF 150
    SESEYKIAMQ SIDNIANNFG LILEHKLAEF TNKIV 185
    Length:185
    Mass (Da):21,007
    Last modified:May 1, 1999 - v1
    Checksum:i91835CC2A6912C6D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15049.1.
    PIRiG71665.
    RefSeqiNP_220973.1. NC_000963.1.

    Genome annotation databases

    EnsemblBacteriaiCAA15049; CAA15049; CAA15049.
    GeneIDi883784.
    KEGGirpr:RP605.
    PATRICi17902027. VBIRicPro72556_0624.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ235272 Genomic DNA. Translation: CAA15049.1 .
    PIRi G71665.
    RefSeqi NP_220973.1. NC_000963.1.

    3D structure databases

    ProteinModelPortali Q9ZCV4.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 272947.RP605.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA15049 ; CAA15049 ; CAA15049 .
    GeneIDi 883784.
    KEGGi rpr:RP605.
    PATRICi 17902027. VBIRicPro72556_0624.

    Phylogenomic databases

    eggNOGi COG0193.
    HOGENOMi HOG000004797.
    KOi K01056.
    OMAi AMHRLHS.
    OrthoDBi EOG6C5RTR.

    Family and domain databases

    Gene3Di 3.40.50.1470. 1 hit.
    HAMAPi MF_00083. Pept_tRNA_hydro_bact.
    InterProi IPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view ]
    PANTHERi PTHR17224. PTHR17224. 1 hit.
    Pfami PF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53178. SSF53178. 1 hit.
    TIGRFAMsi TIGR00447. pth. 1 hit.
    PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Madrid E.

    Entry informationi

    Entry nameiPTH_RICPR
    AccessioniPrimary (citable) accession number: Q9ZCV4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: May 14, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Rickettsia prowazekii
      Rickettsia prowazekii (strain Madrid E): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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