Q9ZCV3 (RL25_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L25

Alternative name(s):
General stress protein CTC

Gene names

Name:	rplY
Synonyms:	ctc
Ordered Locus Names:	RP606

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance By similarity. HAMAP-Rule MF_01334
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18 By similarity.
Sequence similarities	Belongs to the ribosomal protein L25P family. Ctc subfamily.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: InterPro
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	5S rRNA binding Inferred from electronic annotation. Source: InterPro structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	50S ribosomal protein L25 HAMAP-Rule MF_01334		PRO_0000181588

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCV3 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: D01871AD009EDA03	FASTA	203	22,728
	10 20 30 40 50 60 MSGILELEAK SRTEFGTGAA RALRREGRVP AIIYGAGKTP ISISLKEKEI TKYYRKPAFI 70 80 90 100 110 120 SQLINLTIDK KQYKVLPKAV ELHPVTDIVR HVDFVFLEAK TQKMEVPIVY EGKERALGVK 130 140 150 160 170 180 RGGYFNIIKR RVILLCDVNN IPRNVTIDVT NMPIGTSLKS SQVELPKGCS FITKKEFVLA 190 200 TIIGRRGVKT EIEGEQEVAE AIQ

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235272 Genomic DNA. Translation: CAA15050.1.
PIR	H71665.
RefSeq	NP_220974.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZCV3.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP606.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA15050; CAA15050; CAA15050.
GeneID	883776.
KEGG	rpr:RP606.
PATRIC	17902029. VBIRicPro72556_0625.
Phylogenomic databases
eggNOG	COG1825.
HOGENOM	HOG000214907.
KO	K02897.
OMA	RDFTMHV.
ProtClustDB	PRK05618.
Family and domain databases
Gene3D	2.170.120.20. 1 hit. 2.40.240.10. 1 hit.
HAMAP	MF_01334. Ribosomal_L25_CTC.
InterPro	IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR020057. Ribosomal_L25_b-dom. IPR001021. Ribosomal_L25_long. IPR020055. Ribosomal_L25_short. [Graphical view]
Pfam	PF01386. Ribosomal_L25p. 1 hit. [Graphical view]
ProDom	PD012503. Ribosomal_L25. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMs	TIGR00731. ctc_TL5. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL25_RICPR

Accession

Primary (citable) accession number: Q9ZCV3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program