SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ZCR0

- RL22_RICPR

UniProt

Q9ZCR0 - RL22_RICPR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
50S ribosomal protein L22
Gene
rplV, RP654
Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity.UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome By similarity.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22
Gene namesi
Name:rplV
Ordered Locus Names:RP654
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911950S ribosomal protein L22UniRule annotation
PRO_0000125214Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272947.RP654.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCR0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0091.
HOGENOMiHOG000205046.
KOiK02890.
OMAiMKRIRPR.
OrthoDBiEOG6V4GKB.

Family and domain databases

Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B.
InterProiIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZCR0-1 [UniParc]FASTAAdd to Basket

« Hide

MIQKNKNFAT AKAKSIRVSP RKLNLVASFI RNMKVSEALV QLTFSPKRIA    50
KIVKDCLQSA IANAENNLGL DIDRLIITKA TVGKSVVMKR IMPRAKGRAT 100
RINKFFSNLY ITVTEKEDN 119
Length:119
Mass (Da):13,364
Last modified:May 1, 1999 - v1
Checksum:i3055D52DBEF5F0A2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15094.1.
PIRiD71671.
RefSeqiNP_221018.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15094; CAA15094; CAA15094.
GeneIDi883878.
KEGGirpr:RP654.
PATRICi17902135. VBIRicPro72556_0676.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15094.1 .
PIRi D71671.
RefSeqi NP_221018.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZCR0.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272947.RP654.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA15094 ; CAA15094 ; CAA15094 .
GeneIDi 883878.
KEGGi rpr:RP654.
PATRICi 17902135. VBIRicPro72556_0676.

Phylogenomic databases

eggNOGi COG0091.
HOGENOMi HOG000205046.
KOi K02890.
OMAi MKRIRPR.
OrthoDBi EOG6V4GKB.

Family and domain databases

Gene3Di 3.90.470.10. 1 hit.
HAMAPi MF_01331_B. Ribosomal_L22_B.
InterProi IPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view ]
PANTHERi PTHR13501. PTHR13501. 1 hit.
Pfami PF00237. Ribosomal_L22. 1 hit.
[Graphical view ]
SUPFAMi SSF54843. SSF54843. 1 hit.
TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiRL22_RICPR
AccessioniPrimary (citable) accession number: Q9ZCR0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi