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Q9ZCQ6 (RL4_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L4
Gene names
Name:rplD
Ordered Locus Names:RP658
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01328

Forms part of the polypeptide exit tunnel By similarity. HAMAP-Rule MF_01328

Subunit structure

Part of the 50S ribosomal subunit By similarity. HAMAP-Rule MF_01328

Sequence similarities

Belongs to the ribosomal protein L4P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 20720750S ribosomal protein L4 HAMAP-Rule MF_01328
PRO_0000129268

Sequences

Sequence LengthMass (Da)Tools
Q9ZCQ6 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: AA652123EB22797E

FASTA20723,288
        10         20         30         40         50         60 
MKTKILSLAN EEVGEITLNK DIFAVEFIRD DIIKQVIDWQ RAKAMFGNHK TKTVSEVSGT 

        70         80         90        100        110        120 
TKKPFKQKGT GNARQGSLRS VQMRGGGISH GPKVRSHAIK LPKKVRKLGL IHALSEKYAE 

       130        140        150        160        170        180 
EKLLIIDSLK LDKPKTSILV NLLSKFQGQS FFVIDGNKVD INFSLATKNI YNTLIVPQIG 

       190        200 
ANVYDIIRHE YVLLSQEAVS FLEERLR 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235272 Genomic DNA. Translation: CAA15098.1.
PIRH71671.
RefSeqNP_221022.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZCQ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP658.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15098; CAA15098; CAA15098.
GeneID883872.
KEGGrpr:RP658.
PATRIC17902143. VBIRicPro72556_0680.

Phylogenomic databases

eggNOGCOG0088.
HOGENOMHOG000248767.
KOK02926.
OMAVVRSHEH.
OrthoDBEOG6M0T9G.
ProtClustDBPRK05319.

Family and domain databases

Gene3D3.40.1370.10. 1 hit.
HAMAPMF_01328_B. Ribosomal_L4_B.
InterProIPR002136. Ribosomal_L4/L1e.
IPR013005. Ribosomal_L4/L1e_bac-type.
IPR023574. Ribosomal_L4_dom.
[Graphical view]
PANTHERPTHR10746. PTHR10746. 1 hit.
PfamPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMSSF52166. SSF52166. 1 hit.
TIGRFAMsTIGR03953. rplD_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRL4_RICPR
AccessionPrimary (citable) accession number: Q9ZCQ6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names

Ribosomal proteins

Ribosomal proteins families and list of entries