Q9ZCQ6 (RL4_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L4

Gene names

Name:	rplD
Ordered Locus Names:	RP658

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01328 Forms part of the polypeptide exit tunnel By similarity. HAMAP-Rule MF_01328
Subunit structure	Part of the 50S ribosomal subunit By similarity. HAMAP-Rule MF_01328
Sequence similarities	Belongs to the ribosomal protein L4P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	50S ribosomal protein L4 HAMAP-Rule MF_01328		PRO_0000129268

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCQ6 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: AA652123EB22797E	FASTA	207	23,288
	10 20 30 40 50 60 MKTKILSLAN EEVGEITLNK DIFAVEFIRD DIIKQVIDWQ RAKAMFGNHK TKTVSEVSGT 70 80 90 100 110 120 TKKPFKQKGT GNARQGSLRS VQMRGGGISH GPKVRSHAIK LPKKVRKLGL IHALSEKYAE 130 140 150 160 170 180 EKLLIIDSLK LDKPKTSILV NLLSKFQGQS FFVIDGNKVD INFSLATKNI YNTLIVPQIG 190 200 ANVYDIIRHE YVLLSQEAVS FLEERLR

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235272 Genomic DNA. Translation: CAA15098.1.
PIR	H71671.
RefSeq	NP_221022.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZCQ6.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP658.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA15098; CAA15098; CAA15098.
GeneID	883872.
KEGG	rpr:RP658.
PATRIC	17902143. VBIRicPro72556_0680.
Phylogenomic databases
eggNOG	COG0088.
HOGENOM	HOG000248767.
KO	K02926.
OMA	GKAHGPV.
ProtClustDB	PRK05319.
Family and domain databases
Gene3D	3.40.1370.10. 1 hit.
HAMAP	MF_01328_B. Ribosomal_L4_B.
InterPro	IPR002136. Ribosomal_L4/L1e. IPR013005. Ribosomal_L4/L1e_bac-type. IPR023574. Ribosomal_L4_dom. [Graphical view]
PANTHER	PTHR10746. PTHR10746. 1 hit.
Pfam	PF00573. Ribosomal_L4. 1 hit. [Graphical view]
SUPFAM	SSF52166. Ribosomal_L4/L1E. 1 hit.
TIGRFAMs	TIGR03953. rplD_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL4_RICPR

Accession

Primary (citable) accession number: Q9ZCQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program