Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ZCM9

- QUEC_RICPR

UniProt

Q9ZCM9 - QUEC_RICPR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

7-cyano-7-deazaguanine synthase

Gene

queC

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).UniRule annotation

Catalytic activityi

7-carboxy-7-carbaguanine + NH3 + ATP = 7-cyano-7-carbaguanine + ADP + phosphate + H2O.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi192 – 1921ZincUniRule annotation
Metal bindingi202 – 2021ZincUniRule annotation
Metal bindingi205 – 2051ZincUniRule annotation
Metal bindingi208 – 2081ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 1811ATPUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. ligase activity, forming carbon-nitrogen bonds Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. queuosine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Queuosine biosynthesis

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00391.

Names & Taxonomyi

Protein namesi
Recommended name:
7-cyano-7-deazaguanine synthaseUniRule annotation (EC:6.3.4.20UniRule annotation)
Alternative name(s):
7-cyano-7-carbaguanine synthaseUniRule annotation
PreQ(0) synthaseUniRule annotation
Queuosine biosynthesis protein QueCUniRule annotation
Gene namesi
Name:queCUniRule annotation
Ordered Locus Names:RP694
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000002480: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2272277-cyano-7-deazaguanine synthasePRO_0000246914Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272947.RP694.

Structurei

3D structure databases

ProteinModelPortaliQ9ZCM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the QueC family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0603.
HOGENOMiHOG000110564.
KOiK06920.
OMAiCLSCIAR.
OrthoDBiEOG6091HB.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_01633. QueC.
InterProiIPR018317. QueC.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF06508. QueC. 1 hit.
[Graphical view]
PIRSFiPIRSF006293. ExsB. 1 hit.
TIGRFAMsiTIGR00364. TIGR00364. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZCM9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKSVNLLSG GTDSATVLAI ASEMCYEIYA MSFNYGQRNN AELRKVKELI
60 70 80 90 100
KKYNVKQHKI VDIDLRAFGG SALTDDNIDV PYYHGINALP EIVPVTYVPA
110 120 130 140 150
RNTIFLSYAV GFAEVIGSQD IFIGVHTSDS ANYPDCCPEY IQSFEKMVNL
160 170 180 190 200
ATNMGVQGKK ITIHAPLIDM TKEQIIRTGL KLGVDYKNTI SCYSPTEDDL
210 220
SCGNCLACII RLDAFKKNNI QDPIKYV
Length:227
Mass (Da):25,211
Last modified:May 1, 1999 - v1
Checksum:i7EB608D1261BE081
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15131.1.
PIRiA71676.
RefSeqiNP_221055.1. NC_000963.1.

Genome annotation databases

EnsemblBacteriaiCAA15131; CAA15131; CAA15131.
GeneIDi883701.
KEGGirpr:RP694.
PATRICi17902221. VBIRicPro72556_0716.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ235272 Genomic DNA. Translation: CAA15131.1 .
PIRi A71676.
RefSeqi NP_221055.1. NC_000963.1.

3D structure databases

ProteinModelPortali Q9ZCM9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272947.RP694.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA15131 ; CAA15131 ; CAA15131 .
GeneIDi 883701.
KEGGi rpr:RP694.
PATRICi 17902221. VBIRicPro72556_0716.

Phylogenomic databases

eggNOGi COG0603.
HOGENOMi HOG000110564.
KOi K06920.
OMAi CLSCIAR.
OrthoDBi EOG6091HB.

Enzyme and pathway databases

UniPathwayi UPA00391 .

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_01633. QueC.
InterProi IPR018317. QueC.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF06508. QueC. 1 hit.
[Graphical view ]
PIRSFi PIRSF006293. ExsB. 1 hit.
TIGRFAMsi TIGR00364. TIGR00364. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Madrid E.

Entry informationi

Entry nameiQUEC_RICPR
AccessioniPrimary (citable) accession number: Q9ZCM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: May 1, 1999
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3