Q9ZCJ3 (RSMI_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase I
EC=2.1.1.198

Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase
rRNA (cytidine-2'-O-)-methyltransferase RsmI

Gene names

Name:	rsmI
Ordered Locus Names:	RP747

Organism

Rickettsia prowazekii (strain Madrid E)

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	280 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877
Catalytic activity	S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877
Subcellular location	Cytoplasm Potential HAMAP MF_01877.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmI family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	rRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 280	280	Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877		PRO_0000211953

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCJ3 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 65C1E8FE6F723787	FASTA	280	31,844
	10 20 30 40 50 60 MILKSGLYIV STPIGNFEDI TLRAISTLKN SDIILCEDTR ISQKLLAKHY IHTKLQIYND 70 80 90 100 110 120 HSDYKDREYI ISLIKAGNVV SLISDAGTPL ISDPGYKLVR DLRNLNYYIE VVPGVSSPIT 130 140 150 160 170 180 ALTLSSLPTD RFLFSGFLPK TIESKKKIFA ELVNLKATLI FFDTASRLIN TLLLAKEIFG 190 200 210 220 230 240 NREICVAREL TKIYQETKTG DIDEIIEFYK NNILKGEIVL LISGNVQVQN KQINLEKFIE 250 260 270 280 FCLSKNLSSK TIIELAYDKF KDVYSKKEIY SVVHKKKFTA

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed: 9823893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235273 Genomic DNA. Translation: CAA15175.1.
PIR	G71634.
RefSeq	NP_221099.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZCJ3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	883914.
GenomeReviews	Gene locus RP747 in contig AJ235269_GR.
KEGG	rpr:RP747.
PATRIC	17902355. VBIRicPro72556_0781.
Phylogenomic databases
HOGENOM	HBG529058.
OMA	GREMTKI.
ProtClustDB	CLSK871059.
Enzyme and pathway databases
BioCyc	RPRO272947:RP747-MONOMER.
Family and domain databases
HAMAP	MF_01877. 16SrRNA_methyltr_I. [Tree]
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR008189. rRNA_ssu_MeTfrase_I. IPR018063. SAM_MeTrfase_RsmI_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
KO	K07056.
PANTHER	PTHR21091:SF18. PTHR21091:SF18. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF005917. MTase_YraL. 1 hit.
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMs	TIGR00096. TIGR00096. 1 hit.
PROSITE	PS01296. RSMI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMI_RICPR

Accession

Primary (citable) accession number: Q9ZCJ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program