Q9ZCJ1 (TATA_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sec-independent protein translocase protein TatA

Gene names

Name:	tatA
Ordered Locus Names:	RP749

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	54 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system By similarity. HAMAP-Rule MF_00236
Subunit structure	The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity HAMAP-Rule MF_00236.
Sequence similarities	Belongs to the TatA/E family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein secretion Inferred from electronic annotation. Source: InterPro protein transport by the Tat complex Inferred from electronic annotation. Source: HAMAP
Cellular_component	TAT protein transport complex Inferred from electronic annotation. Source: HAMAP integral to plasma membrane Inferred from electronic annotation. Source: HAMAP
Molecular_function	protein transmembrane transporter activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 54	54	Sec-independent protein translocase protein TatA HAMAP-Rule MF_00236		PRO_0000097957
Regions
	Transmembrane	1 – 21	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCJ1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 607EAE2A977FA3C7	FASTA	54	5,884
	10 20 30 40 50 MGMSFSHLLI VLLIIFVLFG AGKLPQVMSD LAKGLKAFKE GMKDDGNDND KTNN

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235273 Genomic DNA. Translation: CAA15177.1.
PIR	A71635.
RefSeq	NP_221101.1. NC_000963.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP749.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA15177; CAA15177; CAA15177.
GeneID	883796.
KEGG	rpr:RP749.
PATRIC	17902359. VBIRicPro72556_0783.
Phylogenomic databases
eggNOG	NOG270103.
HOGENOM	HOG000245363.
KO	K03116.
OMA	MKDDGND.
ProtClustDB	PRK01470.
Family and domain databases
HAMAP	MF_00236. TatA_E.
InterPro	IPR003369. TatA/B/E. IPR006312. TatA_E. [Graphical view]
Pfam	PF02416. MttA_Hcf106. 1 hit. [Graphical view]
TIGRFAMs	TIGR01411. tatAE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TATA_RICPR

Accession

Primary (citable) accession number: Q9ZCJ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program