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Q9ZCH8 (Q9ZCH8_RICPR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] synthase 2 PIRNR PIRNR000447
EC=2.3.1.179 PIRNR PIRNR000447
Gene names
Ordered Locus Names:RP764
OrganismRickettsia prowazekii (strain Madrid E)
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP By similarity. PIRNR PIRNR000447

Catalytic activity

(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]. PIRNR PIRNR000447

Pathway

Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000447

Sequence similarities

Belongs to the beta-ketoacyl-ACP synthases family. PIRNR PIRNR000447 RuleBase RU003694

Sequences

Sequence LengthMass (Da)Tools
Q9ZCH8 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 61842D0C04B63179

FASTA42645,502
        10         20         30         40         50         60 
MSNQNINKRV VITGLGLVTP VGLNVSSTWK NIVGGVSGIK TITEFDTSKL ACKIAGVIDN 

        70         80         90        100        110        120 
SEQNGFKLEN FTQADDINRL SKMDKFIHYG IAAATEAVED SGWLPKDEKS RDRTGLILGS 

       130        140        150        160        170        180 
GIGGLKMIED TSIKLYKENN GKVSPFFIPA SLINLLSGLV SIKYGFSGPN QAAVTACSTG 

       190        200        210        220        230        240 
AHAIGDAMRM IKHGYADVMI AGGAEAPVTP VGIAGFVAAR ALCTKYNDNP EKASRPWDKD 

       250        260        270        280        290        300 
RSGFVMGEGA GIVVLEEYEH AINRGAKIYC EVIGYGSTGD AYHMTAPHPK GRGAYRAMSE 

       310        320        330        340        350        360 
ALQDADITPS MIDYINAHGT STPLGDMIEL DATQKLFLES NPKILMSSTK SSIGHLLGAA 

       370        380        390        400        410        420 
GSVEFIFSVL TIRDQIAPPT LNLENPIDDV KIDLVKFKAR ETVIDYVLSN SFGFGGTNAS 


LVIKKI

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References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed: 9823893] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ235273 Genomic DNA. Translation: CAA15192.1.
PIRH71636.
RefSeqNP_221116.1. NC_000963.1.

3D structure databases

HSSPHSSP built from PDB template 1KAS based on UniProtKB P39435.
ProteinModelPortalQ9ZCH8.
SMRQ9ZCH8. Positions 7-426.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID883755.
GenomeReviewsGene locus RP764 in contig AJ235269_GR.
KEGGrpr:RP764.
PATRIC17902393. VBIRicPro72556_0800.

Phylogenomic databases

HOGENOMHBG757733.
OMAILMSSTK.
ProtClustDBPRK07314.

Enzyme and pathway databases

BioCycRPRO272947:RP764-MONOMER.

Family and domain databases

InterProIPR017568. 3-oxoacyl-ACP_synth-2.
IPR000794. Beta-ketoacyl_synthase.
IPR018201. Ketoacyl_synth_AS.
IPR014031. Ketoacyl_synth_C.
IPR014030. Ketoacyl_synth_N.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
Gene3DG3DSA:3.40.47.10. Thiolase-like_subgr. 2 hits.
KOK09458.
PANTHERPTHR11712. Ketoacyl_synth. 1 hit.
PfamPF00109. ketoacyl-synt. 1 hit.
PF02801. Ketoacyl-synt_C. 1 hit.
[Graphical view]
PIRSFPIRSF000447. KAS_II. 1 hit.
SUPFAMSSF53901. Thiolase-like. 2 hits.
TIGRFAMsTIGR03150. FabF. 1 hit.
PROSITEPS00606. B_KETOACYL_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9ZCH8_RICPR
AccessionPrimary (citable) accession number: Q9ZCH8
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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