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Q9ZCE0 (XERC_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tyrosine recombinase XerC
Gene names
Name:xerC
Ordered Locus Names:RP817
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids By similarity. HAMAP-Rule MF_01808

Subunit structure

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01808.

Sequence similarities

Belongs to the 'phage' integrase family. XerC subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Tyrosine recombinase XerC HAMAP-Rule MF_01808
PRO_0000095323

Sites

Active site1591 By similarity
Active site1821 By similarity
Active site2501 By similarity
Active site2531 By similarity
Active site2761 By similarity
Active site2851O-(3'-phospho-DNA)-tyrosine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZCE0 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 3358B17D33A37BD6

FASTA30535,532
        10         20         30         40         50         60 
MLDISIQELI KQWQKYLILQ KNYSNNTVIA YNNDLKHFLE FMNYYNSELV TLNHIKTADI 

        70         80         90        100        110        120 
RLIRSWLAKR KCENFTASSI ARGLSTVKNF YKFLEKTLLL NNHIIFSIKS PKKAKLLPKG 

       130        140        150        160        170        180 
LSVDDVLISL EHIEEYGNVK WVELRNKALI VLIYAAGLRI SEALSITKLH LQNLEFIKII 

       190        200        210        220        230        240 
GKGSKERIIP WLPLTKNLIT KYLEILPYKL DENEPIFRGR QGKKLQPSVF NRELIKLKRI 

       250        260        270        280        290        300 
YGLPEYLTAH SFRHSFASHL LEYGADLRSI QELLGHKSLS TTQKYTQTSI KHLEAVYNTA 


YPIKK 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235273 Genomic DNA. Translation: CAA15242.1.
PIRB71643.
RefSeqNP_221166.1. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZCE0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP817.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15242; CAA15242; CAA15242.
GeneID883927.
KEGGrpr:RP817.
PATRIC17902502. VBIRicPro72556_0852.

Phylogenomic databases

eggNOGCOG0582.
HOGENOMHOG000045294.
KOK03733.
OMATQIYTGI.
OrthoDBEOG6PZXFP.
ProtClustDBPRK00236.

Family and domain databases

Gene3D1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPMF_01808. Recomb_XerC.
InterProIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMSSF56349. SSF56349. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXERC_RICPR
AccessionPrimary (citable) accession number: Q9ZCE0
Entry history
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names