Q9ZCC8 (FER_RICPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin

Gene names

Name:	fdxA
Ordered Locus Names:	RP829

Organism

Rickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]

Taxonomic identifier

272947 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	109 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions By similarity.
Cofactor	Binds 1 4Fe-4S cluster By similarity. Binds 1 3Fe-4S cluster By similarity.
Sequence similarities	Contains 2 4Fe-4S ferredoxin-type domains.

Ontologies

Keywords
Biological process	Electron transport Transport
Domain	Repeat
Ligand	3Fe-4S 4Fe-4S Iron Iron-sulfur Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	3 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW 4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 109	108	Ferredoxin		PRO_0000159102
Regions
	Domain	2 – 30	29	4Fe-4S ferredoxin-type 1
	Domain	31 – 60	30	4Fe-4S ferredoxin-type 2
Sites
	Metal binding	9	1	Iron-sulfur 1 (3Fe-4S) By similarity
	Metal binding	17	1	Iron-sulfur 1 (3Fe-4S) By similarity
	Metal binding	21	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	40	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	43	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	46	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	50	1	Iron-sulfur 1 (3Fe-4S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9ZCC8 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 67F5A0D4AF37CE96	FASTA	109	12,566
	10 20 30 40 50 60 MTYVVTDECV KCKYTDCVEV CPVDCFYEGE FMLVINPDEC IDCGVCVPDC PIDAIKPESP 70 80 90 100 ELIEWVERAK DFIENHGWKN ITKKKCALPG ADKFKDEKDK FNKYIIKKT

References

[1]

"The genome sequence of Rickettsia prowazekii and the origin of mitochondria." Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G. Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Madrid E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ235273 Genomic DNA. Translation: CAA15254.1.
PIR	F71644.
RefSeq	NP_221178.1. NC_000963.1.
3D structure databases
ProteinModelPortal	Q9ZCC8.
SMR	Q9ZCC8. Positions 2-102.
ModBase	Search...
Protein-protein interaction databases
STRING	272947.RP829.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAA15254; CAA15254; CAA15254.
GeneID	883955.
KEGG	rpr:RP829.
PATRIC	17902530. VBIRicPro72556_0866.
Phylogenomic databases
eggNOG	COG1146.
HOGENOM	HOG000044610.
KO	K05524.
OMA	SPELIEW.
ProtClustDB	CLSK871100.
Family and domain databases
InterPro	IPR001450. 4Fe4S-bd_dom. IPR017896. 4Fe4S_Fe-S-bd. IPR017900. 4Fe4S_Fe_S_CS. IPR000813. 7Fe_ferredoxin. IPR022569. Fd_C. [Graphical view]
Pfam	PF11953. DUF3470. 1 hit. PF00037. Fer4. 1 hit. [Graphical view]
PRINTS	PR00354. 7FE8SFRDOXIN.
PROSITE	PS00198. 4FE4S_FER_1. 1 hit. PS51379. 4FE4S_FER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FER_RICPR

Accession

Primary (citable) accession number: Q9ZCC8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 78 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program