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Q9ZCB1 (SYGB_RICPR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase beta subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase beta subunit
Short name=GlyRS
Gene names
Name:glyS
Ordered Locus Names:RP849
OrganismRickettsia prowazekii (strain Madrid E) [Reference proteome] [HAMAP]
Taxonomic identifier272947 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length665 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00255

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00255.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Sequence caution

The sequence CAA15273.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: InterPro

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 665665Glycine--tRNA ligase beta subunit HAMAP-Rule MF_00255
PRO_0000072924

Sequences

Sequence LengthMass (Da)Tools
Q9ZCB1 [UniParc].

Last modified December 1, 2000. Version 2.
Checksum: A193D931CE7463F5

FASTA66576,216
        10         20         30         40         50         60 
MVSELLLELF SEEIPAFMQK NAEEGYLKIF TKIFEENEIF AKVQVFAGPR RITLHATHVP 

        70         80         90        100        110        120 
KVILPKEEEI KGPSIEAPEI AINGFCKAHN VSKLDLSTKL RNNKLYYFFV KKTKERETKE 

       130        140        150        160        170        180 
ILPKIIIDAI NKYSWTKSMF WGCYKIKWIR PLRNILCIFD GEILPLRFGH LSTNNITYGH 

       190        200        210        220        230        240 
RLTNNKKLEI IDFENYRNKL LENNVILERL KREEIIKVGL LELANAQNLN IKQDVCLIEE 

       250        260        270        280        290        300 
VTGLSEFPIV LLGKIPQKFL ELPEEVIVSV MRTHQKYFCL FDKNGSFAPY FLFVINGRFV 

       310        320        330        340        350        360 
NTELIIQGNE KVLSARLADA LYFYKNDIAK TLESRLDKLK SVIFHTKLGS LKEKVDRITD 

       370        380        390        400        410        420 
ICRYIAPDNI DLIMAAKLCK SDLVSDMVGE FPDLQGIMGY YYAKHEELNE EVAKAIRDHY 

       430        440        450        460        470        480 
KPQGLNDNVP SGNATLLALA DKLDSLVGLI IVGETPNGSG DPYALRRQAL GIIRIIIENK 

       490        500        510        520        530        540 
LEINFINLIS FSVSLYKVSS NSHLDSVISF FEERAKFYFK NDYDITLINA VLDLNLVDTK 

       550        560        570        580        590        600 
FKLDTLKEFL VQDVGKQLLN AYKRVSNIMG NQKITGLVDA SLFSTQYEKE LFEVIQKISQ 

       610        620        630        640        650        660 
QIIVIIANKD YQKALNLLSS LLKPITSFFD NVLVNDSDPK IAQNRLSLLQ NTCEVFDKVA 


KFCRL 

« Hide

References

[1]"The genome sequence of Rickettsia prowazekii and the origin of mitochondria."
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.
Nature 396:133-140(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Madrid E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ235273 Genomic DNA. Translation: CAA15273.1. Different initiation.
PIRA71647.
RefSeqNP_221197.2. NC_000963.1.

3D structure databases

ProteinModelPortalQ9ZCB1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272947.RP849.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAA15273; CAA15273; CAA15273.
GeneID883343.
KEGGrpr:RP849.
PATRIC17902574. VBIRicPro72556_0887.

Phylogenomic databases

eggNOGCOG0751.
HOGENOMHOG000264304.
KOK01879.
OrthoDBEOG661H9S.
ProtClustDBPRK01233.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
HAMAPMF_00255. Gly_tRNA_synth_beta.
InterProIPR008909. DALR_anticod-bd.
IPR015944. Gly-tRNA-synth_bsu.
IPR006194. Gly-tRNA-synth_heterodimer.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PfamPF05746. DALR_1. 1 hit.
PF02092. tRNA_synt_2f. 1 hit.
[Graphical view]
PRINTSPR01045. TRNASYNTHGB.
SMARTSM00836. DALR_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00211. glyS. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGB_RICPR
AccessionPrimary (citable) accession number: Q9ZCB1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: December 1, 2000
Last modified: April 16, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia prowazekii

Rickettsia prowazekii (strain Madrid E): entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries