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Protein

Glycine--tRNA ligase beta subunit

Gene

glyS

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase beta subunit (EC:6.1.1.14)
Alternative name(s):
Glycyl-tRNA synthetase beta subunit
Short name:
GlyRS
Gene namesi
Name:glyS
Ordered Locus Names:RP849
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000729241 – 665Glycine--tRNA ligase beta subunitAdd BLAST665

Proteomic databases

PRIDEiQ9ZCB1

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.By similarity

Protein-protein interaction databases

STRINGi272947.RP849

Structurei

3D structure databases

ProteinModelPortaliQ9ZCB1
SMRiQ9ZCB1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C38 Bacteria
COG0751 LUCA
HOGENOMiHOG000264304
KOiK01879

Family and domain databases

HAMAPiMF_00255 Gly_tRNA_synth_beta, 1 hit
InterProiView protein in InterPro
IPR008909 DALR_anticod-bd
IPR015944 Gly-tRNA-synth_bsu
IPR006194 Gly-tRNA-synth_heterodimer
PANTHERiPTHR30075 PTHR30075, 1 hit
PfamiView protein in Pfam
PF05746 DALR_1, 1 hit
PF02092 tRNA_synt_2f, 1 hit
PRINTSiPR01045 TRNASYNTHGB
SMARTiView protein in SMART
SM00836 DALR_1, 1 hit
TIGRFAMsiTIGR00211 glyS, 1 hit
PROSITEiView protein in PROSITE
PS50861 AA_TRNA_LIGASE_II_GLYAB, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZCB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSELLLELF SEEIPAFMQK NAEEGYLKIF TKIFEENEIF AKVQVFAGPR
60 70 80 90 100
RITLHATHVP KVILPKEEEI KGPSIEAPEI AINGFCKAHN VSKLDLSTKL
110 120 130 140 150
RNNKLYYFFV KKTKERETKE ILPKIIIDAI NKYSWTKSMF WGCYKIKWIR
160 170 180 190 200
PLRNILCIFD GEILPLRFGH LSTNNITYGH RLTNNKKLEI IDFENYRNKL
210 220 230 240 250
LENNVILERL KREEIIKVGL LELANAQNLN IKQDVCLIEE VTGLSEFPIV
260 270 280 290 300
LLGKIPQKFL ELPEEVIVSV MRTHQKYFCL FDKNGSFAPY FLFVINGRFV
310 320 330 340 350
NTELIIQGNE KVLSARLADA LYFYKNDIAK TLESRLDKLK SVIFHTKLGS
360 370 380 390 400
LKEKVDRITD ICRYIAPDNI DLIMAAKLCK SDLVSDMVGE FPDLQGIMGY
410 420 430 440 450
YYAKHEELNE EVAKAIRDHY KPQGLNDNVP SGNATLLALA DKLDSLVGLI
460 470 480 490 500
IVGETPNGSG DPYALRRQAL GIIRIIIENK LEINFINLIS FSVSLYKVSS
510 520 530 540 550
NSHLDSVISF FEERAKFYFK NDYDITLINA VLDLNLVDTK FKLDTLKEFL
560 570 580 590 600
VQDVGKQLLN AYKRVSNIMG NQKITGLVDA SLFSTQYEKE LFEVIQKISQ
610 620 630 640 650
QIIVIIANKD YQKALNLLSS LLKPITSFFD NVLVNDSDPK IAQNRLSLLQ
660
NTCEVFDKVA KFCRL
Length:665
Mass (Da):76,216
Last modified:December 1, 2000 - v2
Checksum:iA193D931CE7463F5
GO

Sequence cautioni

The sequence CAA15273 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ235273 Genomic DNA Translation: CAA15273.1 Different initiation.
PIRiA71647
RefSeqiNP_221197.2, NC_000963.1

Genome annotation databases

EnsemblBacteriaiCAA15273; CAA15273; CAA15273
GeneIDi883343
KEGGirpr:RP849
PATRICifig|272947.5.peg.887

Similar proteinsi

Entry informationi

Entry nameiSYGB_RICPR
AccessioniPrimary (citable) accession number: Q9ZCB1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: December 1, 2000
Last modified: May 23, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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