Q9ZBY8 (PATR_STRCO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Synonyms:	hisC2
Ordered Locus Names:	SCO3944
ORF Names:	SCD78.11

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_0000153521
Amino acid modifications
	Modified residue	223	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9ZBY8 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 7A3C98C354E56472	FASTA	359	38,794
	10 20 30 40 50 60 MSETSPKLRA ELEGIPTYKP GKPAAADGPV AYKLSSNENP YPPLPGVMET VTAAAASFNR 70 80 90 100 110 120 YPDMACTSLM AELSDRFGVP LAHLATGTGS VGVAQQLIQA TSGPGDEVIY AWRSFEAYPI 130 140 150 160 170 180 ITQISGARSV QVPLTPGEVH DLDAMADAIT DRTRLIFVCN PNNPTGTVVR RAELERFLDR 190 200 210 220 230 240 VPSDVLVVLD EAYREFIRDA EVPDGVEFYR ERPNVCVLRT FSKAYGLAGL RVGFAIAHEP 250 260 270 280 290 300 VAAALRKTAV PFGVSQIAQE AAIASLRAED ELIGRVGSLV CERARVADAL RAQGWTVPES 310 320 330 340 350 QANFVWLRLG ERTLAFANAC EQAGVVVRPF AGEGVRVTVG ESEANDIFLK VSEEFRKEL

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939118 Genomic DNA. Translation: CAA22216.1.
PIR	T36050.
RefSeq	NP_628128.1. NC_003888.3.
3D structure databases
ProteinModelPortal	Q9ZBY8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1099380.
GenomeReviews	Gene locus SCO3944 in contig AL645882_GR.
KEGG	sco:SCO3944.
NMPDR	fig|100226.1.peg.3901.
PATRIC	23737670. VBIStrCoe124346_4016.
Phylogenomic databases
HOGENOM	HBG646350.
OMA	NNTKIVW.
PhylomeDB	Q9ZBY8.
ProtClustDB	PRK03321.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001176. ACC_synthase. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_STRCO

Accession

Primary (citable) accession number: Q9ZBY8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program