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Protein

Beta-galactosidase

Gene

SCO6457

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotationSAAS annotation, Hydrolase

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotationSAAS annotation (EC:3.2.1.23UniRule annotationSAAS annotation)
Alternative name(s):
LactaseUniRule annotation
Gene namesi
Ordered Locus Names:SCO6457Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 50Sequence analysisAdd BLAST50
ChainiPRO_500433737451 – 1307Beta-galactosidaseSequence analysisAdd BLAST1257

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO6457.

Structurei

3D structure databases

ProteinModelPortaliQ9ZBF6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini676 – 806LamGLInterPro annotationAdd BLAST131
Domaini1015 – 1288Bgal_small_NInterPro annotationAdd BLAST274

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105CNT. Bacteria.
COG3250. LUCA.
HOGENOMiHOG000252444.
InParanoidiQ9ZBF6.
KOiK01190.
OMAiWCDHGIL.
OrthoDBiPOG091H07QB.
PhylomeDBiQ9ZBF6.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.10. 2 hits.
2.70.98.10. 1 hit.
InterProiView protein in InterPro
IPR004199. B-gal_small/dom_5.
IPR036156. Beta-gal/glucu_dom_sf.
IPR013320. ConA-like_dom_sf.
IPR011013. Gal_mutarotase_sf_dom.
IPR008979. Galactose-bd-like_sf.
IPR014718. GH-type_carb-bd.
IPR006101. Glyco_hydro_2.
IPR023232. Glyco_hydro_2_AS.
IPR006103. Glyco_hydro_2_cat.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR032312. LacZ_4.
IPR006558. LamG-like.
IPR006311. TAT_signal.
PfamiView protein in Pfam
PF02929. Bgal_small_N. 1 hit.
PF16353. DUF4981. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 2 hits.
PF02837. Glyco_hydro_2_N. 1 hit.
PRINTSiPR00132. GLHYDRLASE2.
SMARTiView protein in SMART
SM01038. Bgal_small_N. 1 hit.
SM00560. LamGL. 1 hit.
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEiView protein in PROSITE
PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
PS51318. TAT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZBF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPHSPVSPAE SPAPQPGRPR PVVSRRRLLE GGAAVLGALA LSASPLTAQA
60 70 80 90 100
AVRRAAADEP PEWNDFGVFR LGTQPPHATL TPYADVEQAL AGDRARSPYR
110 120 130 140 150
LSLDGTWKFA YADRPEDRDA DFHRTDVDDG DWGTIPVPSV WQLHGHDFPI
160 170 180 190 200
YLNITYPYWG PNGQGEEPQP PAAPTRYNPV GQYRRTFTVP RDWRGRRTFL
210 220 230 240 250
HFEGVKSAHY VWINGELAGY DEDSYTPSEY DVTDLLKPGT NQIAVEVYRY
260 270 280 290 300
SDGDWMEDQD MIRLSGIFRS VHLYSTPAVH LRDFKLDTPL DDTYTGAELA
310 320 330 340 350
VTASVRAYGE GGTGRYTVET QLYDARGHAV WSRPLQQPVD VGGARAGEDV
360 370 380 390 400
TVRAAKAVPK PRLWSAEHPD LYTAVLRLRD PAGKVTETLS HRVGFREFAL
410 420 430 440 450
KDGLMRINGE PVSIRGTNRH EMHPARGTAL TREDMVEDIK IIKRMNMNSV
460 470 480 490 500
RTSHYPNNPY WLELADEYGL YLVDETNLET HGIRGEYPGD HPDWTAACVA
510 520 530 540 550
RAQNMVHRDK NHASVVIWSL GNEAGGGSTF SAMHDWIRSY DDTRVIQYEG
560 570 580 590 600
DDRPGVSDIR SEMYDSPQRV EQRAKDTSDT RPYVMIEYAH SMGNSTGNFK
610 620 630 640 650
KYWDVVRRYD VLQGGWIWDF VDQSLYTPVP ARTLLTEAGP AGLRGEILAT
660 670 680 690 700
RGTLDRDEGL SGITVFERHD SLDLTGSLTL EAWVTPHVTG YHQPIIAKGD
710 720 730 740 750
TQYALKQNGR TLEFFIHSEG QWITANWTVP EDWTGREHHL AGVFDADAGT
760 770 780 790 800
LTLYVDGVER ATRTTDRRPS SNTAPLALAS DADNQVREFS GTVRRARVYA
810 820 830 840 850
RALGAAELAS ESRGPGDDGV RFWFDAATVK TSTRRPRDKT FLAYGGDWGD
860 870 880 890 900
NPNDGAFVAD GIVTADRGHT GKAAEVKRVY QAIDAARTPG GGPGAVTLTN
910 920 930 940 950
EYLFTRLREF DGHWELVADG EVVRRGRLTR DQLDVAPRSS KDITVPVRLP
960 970 980 990 1000
GRPGPGTEYF LQLSFTTKES TPWAKAGFEV ARRQLPVAAD VPAVTPVRAA
1010 1020 1030 1040 1050
SVPALRHEDR DREVEVTGRG FSVTVDKRTG TISSYEAKGT RLITSGPVPN
1060 1070 1080 1090 1100
FWRAPTDNDK GNGQHTRNQT WRDAGARRKV TGVIVRALGD RAVEIKVTGT
1110 1120 1130 1140 1150
LPTSVESTYG TTYTVFGNGE IKVDNTLHPG AANLPYIPEV GTMLFLPRGL
1160 1170 1180 1190 1200
DRVHWYGRGP EENHWDRNDG TDVGRYSGTV AEQWTPYIRP QENGNKTDVR
1210 1220 1230 1240 1250
WIALTDRHGV GLLASGEPLL EANASYFTPE DLSAGVRHDY QLTPRDEVVL
1260 1270 1280 1290 1300
RLNHRQMGVG GDNSWGAHTH DEFKLFADRD YAYTYRLRPL TDVRDATRAS

RRPTATE
Length:1,307
Mass (Da):145,522
Last modified:May 1, 1999 - v1
Checksum:i86DF428BD21AFD87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939127 Genomic DNA. Translation: CAA22766.1.
PIRiT35944.
RefSeqiNP_630542.1. NC_003888.3.
WP_011030935.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAA22766; CAA22766; CAA22766.
GeneIDi1101896.
KEGGisco:SCO6457.
PATRICifig|100226.15.peg.6557.

Similar proteinsi

Entry informationi

Entry nameiQ9ZBF6_STRCO
AccessioniPrimary (citable) accession number: Q9ZBF6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: November 22, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported