Reviewed,
UniProtKB/Swiss-Prot Q9ZB09 (GALT_STRTR)
Last modified
June 16, 2009.
Version 51.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Galactose-1-phosphate uridylyltransferase Short name=Gal-1-P uridylyltransferase EC=2.7.7.12 Alternative name(s): UDP-glucose--hexose-1-phosphate uridylyltransferase | ||
| Gene names |
| ||
| Organism | Streptococcus thermophilus | ||
| Taxonomic identifier | 1308 [NCBI] | ||
| Taxonomic lineage | Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus |
Protein attributes
| Sequence length | 493 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571 |
| Pathway | Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571 |
| Subcellular location | Cytoplasm Potential. |
| Sequence similarities | Belongs to the galactose-1-phosphate uridylyltransferase type 2 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Galactose metabolism |
| Cellular component | Cytoplasm |
| Molecular function | Nucleotidyltransferase Transferase |
| Gene Ontology (GO) | |
| Biological process | galactose metabolic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 493 | 493 | Galactose-1-phosphate uridylyltransferase HAMAP MF_00571 | PRO_0000169919 | |||||
Natural variations | |||||||||
| Natural variant | 42 | 1 | I → V in strain: SMQ-301. | ||||||
| Natural variant | 70 | 1 | K → N in strain: SMQ-301. | ||||||
| Natural variant | 107 | 1 | I → T in strain: SMQ-301. | ||||||
| Natural variant | 243 | 1 | V → A in strain: SMQ-301. | ||||||
| Natural variant | 480 | 1 | A → D in strain: SMQ-301. | ||||||
Sequences
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References
| [1] | "Activation of silent gal genes in the lac-gal regulon of Streptococcus thermophilus." Vaughan E.E., van den Bogaard P.T.C., Catzeddu P., Kuipers O.P., de Vos W.M. J. Bacteriol. 183:1184-1194(2001) [PubMed: 11157930] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CNRZ 302. |
| [2] | "Galactose and lactose genes from the galactose-positive bacterium Streptococcus salivarius and the phylogenetically related galactose-negative bacterium Streptococcus thermophilus: organization, sequence, transcription, and activity of the gal gene products." Vaillancourt K., Moineau S., Frenette M., Lessard C., Vadeboncoeur C. J. Bacteriol. 184:785-793(2002) [PubMed: 11790749] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SMQ-301. |
Cross-references
Sequence databases | |
|---|---|
| U61402 Genomic DNA. Translation: AAD00094.1. AF389475 Genomic DNA. Translation: AAL67297.1. | |
3D structure databases | |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 2.7.7.12. 1164. |
Family and domain databases | |
| HAMAP | MF_00571. [Tree] |
| InterPro | IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view] |
| Pfam | PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view] |
| PIRSF | PIRSF006005. GalT_BS. 1 hit. |
| TIGRFAMs | TIGR01239. galT_2. 1 hit. |
| PROSITE | PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GALT_STRTR | ||||||||
| Accession | Primary (citable) accession number: Q9ZB09 Secondary accession number(s): Q8VS86 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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