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Q9ZB09 (GALT_STRTR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 31, 2011. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Galactose-1-phosphate uridylyltransferase

Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12
Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase
Gene names
Name:galT
OrganismStreptococcus thermophilus
Taxonomic identifier1308 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571

Pathway

Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571

Subcellular location

Cytoplasm Potential HAMAP MF_00571.

Sequence similarities

Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Galactose metabolism
   Cellular componentCytoplasm
   Molecular functionNucleotidyltransferase
Transferase
Gene Ontology (GO)
   Biological processgalactose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionUDP-glucose:hexose-1-phosphate uridylyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 493493Galactose-1-phosphate uridylyltransferase HAMAP MF_00571
PRO_0000169919

Natural variations

Natural variant421I → V in strain: SMQ-301.
Natural variant701K → N in strain: SMQ-301.
Natural variant1071I → T in strain: SMQ-301.
Natural variant2431V → A in strain: SMQ-301.
Natural variant4801A → D in strain: SMQ-301.

Sequences

Sequence LengthMass (Da)Tools
Q9ZB09 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 203F5449A40A5FEF

FASTA49355,413
        10         20         30         40         50         60 
MAENLVNTFV TQVIENSDYE ELDRIYLTNK VFTLVGEGVA DIETDSSELI DLKDQLLQAG 

        70         80         90        100        110        120 
VKAGSVGELK EEQDIIGAQL MDLITPRPSV VNRNFWDTYK SNPEQAIADF YAQSKRNDYV 

       130        140        150        160        170        180 
KVKAIAQNIA YKAPTKYGDL EITINLSKPE KDPKAIAAAK NAVASDYPKC QLCMENEGYL 

       190        200        210        220        230        240 
GRINHPARSN HRVVRFQMED KEWGFQYSPY AYFNEHSIFF YGKHEPMHIS PLTFGRLLTI 

       250        260        270        280        290        300 
VEVFPGYFAG SNADLPIVGG SILTHEHYQG GRHTFPMEVA GIKEKVSFDG YSDVEAGIVN 

       310        320        330        340        350        360 
WPMSVLRLRS EDKGRLIALA TKILNCWRGY SDEKAGVLAE SDGQPHHTIT PIARRKDGKF 

       370        380        390        400        410        420 
ELDLVLRDNQ TSEEYPDGIY HPHKDVQHIK KENIGLIEVM GLAILPPRLK TELKDVEDYL 

       430        440        450        460        470        480 
LGQGNQVAPI HQEWADELKA QNPNITAEEV TEVVRQSVAD IFARVLEDAG VYKTNSEGLA 

       490 
QFKAFVDFVN LAD 

« Hide

References

[1]"Activation of silent gal genes in the lac-gal regulon of Streptococcus thermophilus."
Vaughan E.E., van den Bogaard P.T.C., Catzeddu P., Kuipers O.P., de Vos W.M.
J. Bacteriol. 183:1184-1194(2001) [PubMed: 11157930] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CNRZ 302.
[2]"Galactose and lactose genes from the galactose-positive bacterium Streptococcus salivarius and the phylogenetically related galactose-negative bacterium Streptococcus thermophilus: organization, sequence, transcription, and activity of the gal gene products."
Vaillancourt K., Moineau S., Frenette M., Lessard C., Vadeboncoeur C.
J. Bacteriol. 184:785-793(2002) [PubMed: 11790749] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SMQ-301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U61402 Genomic DNA. Translation: AAD00094.1.
AF389475 Genomic DNA. Translation: AAL67297.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

HAMAPMF_00571. GalP_UDP_trans.
[Tree]
InterProIPR000766. GalP_uridyl_Trfase_II.
IPR023425. GalP_uridyl_Trfase_II_CS.
IPR005850. GalP_Utransf_C.
IPR005849. GalP_Utransf_N.
[Graphical view]
PfamPF02744. GalP_UDP_tr_C. 1 hit.
PF01087. GalP_UDP_transf. 1 hit.
[Graphical view]
PIRSFPIRSF006005. GalT_BS. 1 hit.
TIGRFAMsTIGR01239. GalT_2. 1 hit.
PROSITEPS01163. GAL_P_UDP_TRANSF_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGALT_STRTR
AccessionPrimary (citable) accession number: Q9ZB09
Secondary accession number(s): Q8VS86
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: May 31, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families