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Q9ZAI3 (Q9ZAI3_9ACTO) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-xylopyranose = D-xylulose. HAMAP-Rule MF_00455 RuleBase RU000609 SAAS SAAS001998

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455 RuleBase RU000610

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455 RuleBase RU000610.

Sequence similarities

Belongs to the xylose isomerase family. HAMAP-Rule MF_00455 RuleBase RU000609

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site541 By similarity HAMAP-Rule MF_00455
Active site571 By similarity HAMAP-Rule MF_00455
Metal binding1811Magnesium PDB 4HHL PDB 4HHM
Metal binding1811Magnesium 1 By similarity HAMAP-Rule MF_00455
Metal binding2171Cobalt PDB 4HHL PDB 4HHM
Metal binding2171Magnesium PDB 4HHL PDB 4HHM
Metal binding2171Magnesium 1 By similarity HAMAP-Rule MF_00455
Metal binding2171Magnesium 2 By similarity HAMAP-Rule MF_00455
Metal binding2201Cobalt; via tele nitrogen PDB 4HHL PDB 4HHM
Metal binding2201Magnesium 2 By similarity HAMAP-Rule MF_00455
Metal binding2451Magnesium PDB 4HHL PDB 4HHM
Metal binding2451Magnesium 1 By similarity HAMAP-Rule MF_00455
Metal binding2551Cobalt PDB 4HHL PDB 4HHM
Metal binding2551Magnesium 2 By similarity HAMAP-Rule MF_00455
Metal binding2571Cobalt PDB 4HHL PDB 4HHM
Metal binding2571Magnesium 2 By similarity HAMAP-Rule MF_00455
Metal binding2871Magnesium PDB 4HHL PDB 4HHM
Metal binding2871Magnesium 1 By similarity HAMAP-Rule MF_00455

Sequences

Sequence LengthMass (Da)Tools
Q9ZAI3 [UniParc].

Last modified March 1, 2004. Version 2.
Checksum: 034009333C53DE5B

FASTA38842,946
        10         20         30         40         50         60 
MNYQPTPEDR FTFGLWTVGW QGRDPFGDAT RPALDPVEAV QRLAELGAYG VTFHDDDLIP 

        70         80         90        100        110        120 
FGASDTEREA HVKRFRQALD ATGMTVPMAT TNLFTHPVFK DGAFTANDRD VRRYALRKTI 

       130        140        150        160        170        180 
RNIDLAVELG AKVYVAWGGR EGAESGAAKD VRAALDRMKE AFDLLGEYVT SQGYDIRFAI 

       190        200        210        220        230        240 
EPKPNEPRGD ILLPTIGHAL AFIERLERPE LYGVNPEVGH EQMAGLNFPH GIAQALWAGK 

       250        260        270        280        290        300 
LFHIDLNGQS GIKYDQDLRF GAGDLRAAFW LVDLLESAGW EGPRHFDFKP PRTEDIDGVW 

       310        320        330        340        350        360 
ASAAGCMRNY LILKERAAAF RADPEVQEAL RAARLDQLAE PTAADGLQAL LADRTAYEDF 

       370        380 
DVDAAAARGM AFERLDQLAM DHLLGARG 

« Hide

References

[1]Belghith-Srih K.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SK EMBL CAA75672.2.
[2]"Identification of critical residues for the activity and thermostability of Streptomyces sp. SK glucose isomerase."
Ben Hlima H., Bejar S., Riguet J., Haser R., Aghajari N.
Appl. Microbiol. Biotechnol. 97:9715-9726(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS) IN COMPLEX WITH COBALT AND MAGNESIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y15518 Genomic DNA. Translation: CAA75672.2.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4HHLX-ray1.73A/B1-388[»]
4HHMX-ray2.15A/B/C/D/E/F/G/H1-388[»]
ProteinModelPortalQ9ZAI3.
SMRQ9ZAI3. Positions 2-387.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. SSF51658. 1 hit.
TIGRFAMsTIGR02631. xylA_Arthro. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9ZAI3_9ACTO
AccessionPrimary (citable) accession number: Q9ZAI3
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: March 1, 2004
Last modified: June 11, 2014
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)