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Protein

Aldehyde dehydrogenase

Gene

Rru_A0931

Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei262 – 2621By similarity
Active sitei301 – 3011By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi218 – 2247NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRRUB269796:GCN1-952-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:Rru_A0931
OrganismiRhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Taxonomic identifieri269796 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
ProteomesiUP000001929 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 506506Aldehyde dehydrogenasePRO_0000056454Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269796.Rru_A0931.

Structurei

3D structure databases

ProteinModelPortaliQ9ZA11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00138.
OMAiHLIMEAA.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZA11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYAAPGTAD AIFAFKPRYD NFIDGTWQPP VRGEYFDNVT PITGKVFCKA
60 70 80 90 100
ARSTEEDITL ALDAAHAAAD RWGRTTAAER ALILNRIADR LQDNLETLAY
110 120 130 140 150
VESIDNGKPI RETLAADIPL AIDHFRYFAA CIRAQEGSLS QIDETTIAYH
160 170 180 190 200
FNEPLGVVGQ IIPWNFPILM ATWKLAPALA AGNCIVLKPA EQTPISILVL
210 220 230 240 250
TELIADLLPP GVLNVVNGFG LEAGKPLASS KRIAKIAFTG ETATGRLIMQ
260 270 280 290 300
YASQNLIPVT LELGGKSPNV FFDDIASADD SFFDKAVEGF VMFALNQGEI
310 320 330 340 350
CTCPSRALIH ESLYDRFIER ALARVAVIKQ GSPLDTETMI GAQASTEQMD
360 370 380 390 400
KILSYMDIGR EEGATVLAGG ARAELGGELD GGYYVQPTVF KGNNSMRIFQ
410 420 430 440 450
EEIFGPVVAV TTFKDEDEAL HLANDTHYGL GSGVWTRDGN RAFRFGRGIK
460 470 480 490 500
AGRVWTNCYH LYPAHAAFGG YKQSGIGREN HHMMLDHYQQ TKNLLVSYDP

KAMGFF
Length:506
Mass (Da):55,419
Last modified:March 21, 2006 - v2
Checksum:i8EBD79F820B149FD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti165 – 1651N → K in BAA75070 (Ref. 1) Curated
Sequence conflicti245 – 2451G → A in BAA75070 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006976 Genomic DNA. Translation: BAA75070.1.
CP000230 Genomic DNA. Translation: ABC21732.1.
RefSeqiWP_011388686.1. NC_007643.1.
YP_426019.1. NC_007643.1.

Genome annotation databases

EnsemblBacteriaiABC21732; ABC21732; Rru_A0931.
GeneIDi3834388.
KEGGirru:Rru_A0931.
PATRICi23325456. VBIRhoRub82919_0987.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006976 Genomic DNA. Translation: BAA75070.1.
CP000230 Genomic DNA. Translation: ABC21732.1.
RefSeqiWP_011388686.1. NC_007643.1.
YP_426019.1. NC_007643.1.

3D structure databases

ProteinModelPortaliQ9ZA11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269796.Rru_A0931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC21732; ABC21732; Rru_A0931.
GeneIDi3834388.
KEGGirru:Rru_A0931.
PATRICi23325456. VBIRhoRub82919_0987.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00138.
OMAiHLIMEAA.
OrthoDBiEOG6BS8QW.

Enzyme and pathway databases

BioCyciRRUB269796:GCN1-952-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of aldehyde dehydrogenase gene from photosynthetic bacterium Rhodospirillum rubrum."
    Okibe N., Amada K., Morikawa M., Kanaya S.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
    , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
    Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1.

Entry informationi

Entry nameiALDH_RHORT
AccessioniPrimary (citable) accession number: Q9ZA11
Secondary accession number(s): Q2RVW3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: March 21, 2006
Last modified: May 27, 2015
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.