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Q9ZA11 (ALDH_RHORT) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aldehyde dehydrogenase

EC=1.2.1.3
Gene names
Ordered Locus Names:Rru_A0931
OrganismRhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Reference proteome] [HAMAP]
Taxonomic identifier269796 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Protein attributes

Sequence length506 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 506506Aldehyde dehydrogenase
PRO_0000056454

Regions

Nucleotide binding218 – 2247NAD By similarity

Sites

Active site2621 By similarity
Active site3011 By similarity

Experimental info

Sequence conflict1651N → K in BAA75070. Ref.1
Sequence conflict2451G → A in BAA75070. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9ZA11 [UniParc].

Last modified March 21, 2006. Version 2.
Checksum: 8EBD79F820B149FD

FASTA50655,419
        10         20         30         40         50         60 
MLYAAPGTAD AIFAFKPRYD NFIDGTWQPP VRGEYFDNVT PITGKVFCKA ARSTEEDITL 

        70         80         90        100        110        120 
ALDAAHAAAD RWGRTTAAER ALILNRIADR LQDNLETLAY VESIDNGKPI RETLAADIPL 

       130        140        150        160        170        180 
AIDHFRYFAA CIRAQEGSLS QIDETTIAYH FNEPLGVVGQ IIPWNFPILM ATWKLAPALA 

       190        200        210        220        230        240 
AGNCIVLKPA EQTPISILVL TELIADLLPP GVLNVVNGFG LEAGKPLASS KRIAKIAFTG 

       250        260        270        280        290        300 
ETATGRLIMQ YASQNLIPVT LELGGKSPNV FFDDIASADD SFFDKAVEGF VMFALNQGEI 

       310        320        330        340        350        360 
CTCPSRALIH ESLYDRFIER ALARVAVIKQ GSPLDTETMI GAQASTEQMD KILSYMDIGR 

       370        380        390        400        410        420 
EEGATVLAGG ARAELGGELD GGYYVQPTVF KGNNSMRIFQ EEIFGPVVAV TTFKDEDEAL 

       430        440        450        460        470        480 
HLANDTHYGL GSGVWTRDGN RAFRFGRGIK AGRVWTNCYH LYPAHAAFGG YKQSGIGREN 

       490        500 
HHMMLDHYQQ TKNLLVSYDP KAMGFF 

« Hide

References

« Hide 'large scale' references
[1]"Cloning of aldehyde dehydrogenase gene from photosynthetic bacterium Rhodospirillum rubrum."
Okibe N., Amada K., Morikawa M., Kanaya S.
Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB006976 Genomic DNA. Translation: BAA75070.1.
CP000230 Genomic DNA. Translation: ABC21732.1.
RefSeqYP_426019.1. NC_007643.1.

3D structure databases

ProteinModelPortalQ9ZA11.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269796.Rru_A0931.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC21732; ABC21732; Rru_A0931.
GeneID3834388.
KEGGrru:Rru_A0931.
PATRIC23325456. VBIRhoRub82919_0987.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00128.
OMAVAYHIYE.
OrthoDBEOG6BS8QW.
ProtClustDBCLSK861644.

Enzyme and pathway databases

BioCycRRUB269796:GCN1-952-MONOMER.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALDH_RHORT
AccessionPrimary (citable) accession number: Q9ZA11
Secondary accession number(s): Q2RVW3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: March 21, 2006
Last modified: November 13, 2013
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families