Q9Z9Q7 (MQO_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	BH3960

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128706

Sequences

	Sequence		Length	Mass (Da)
	Q9Z9Q7 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 4B4E4EF094AA4B6F	FASTA	500	55,081
	10 20 30 40 50 60 MSSIQNKTDV ILIGAGIMSA TLGSLLKELK PEWEIKVFEK LANAGEESSN EWNNAGTGHA 70 80 90 100 110 120 ALCELNYTAE KSDGTIDISK AVKINEQFQI SRQFWAYLVS QNLISNPQDF IMPIPHMSLV 130 140 150 160 170 180 QGEDNVAYLK KRFKALSNIP LFEGMEFSND PEKLKEWIPL VMEGRTSNEP IAATKIDSGT 190 200 210 220 230 240 DVNFGALTRM LFEHLKEQNV EVHYKHSVKD IKRTSDGSWS VKVQEIESGT IEYHTANFVF 250 260 270 280 290 300 IGGGGGSLPL LQKTGIPESK NIGGFPVSGL FMVCNNPEVV EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRYIDN KKSLLFGPFA GFSPKFLKTG SNFDLIGSVK PYNVFTMLAA GAKEMSLTKY 370 380 390 400 410 420 LIQQVMLSKE KRMAELREFM PNAKSEDWDI VVAGQRVQVI KDTEAGGKGT LQFGTEVVSS 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVH VMLEVLEKCF PHHMLEWQPK IKEMIPSYGV SLAENRELFQ 490 500 EIHQSTAEAL GLSEKELVHS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An improved physical and genetic map of the genome of alkaliphilic Bacillus sp. C-125." Takami H., Nakasone K., Hirama C., Takaki Y., Masui N., Fuji F., Nakamura Y., Inoue A. Extremophiles 3:21-28(1999) [PubMed: 10086841] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
[2]	"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB013369 Genomic DNA. Translation: BAA75375.1. BA000004 Genomic DNA. Translation: BAB07679.1.
PIR	T44345.
RefSeq	NP_244828.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9Z9Q7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050693; EBBACP00000049332; EBBACG00000050684.
GeneID	893088.
GenomeReviews	Gene locus BH3960 in contig BA000004_GR.
KEGG	bha:BH3960.
NMPDR	fig|272558.1.peg.3960.
PATRIC	18945248. VBIBacHal18977_4122.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000004051.
HOGENOM	HBG289663.
OMA	KKWVPLM.
PhylomeDB	Q9Z9Q7.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	BHAL272558:BH3960-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BACHD

Accession

Primary (citable) accession number: Q9Z9Q7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program