Q9Z9M1 (RPOC_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit beta'
Short name=RNAP subunit beta'
EC=2.7.7.6

Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'

Gene names

Name:	rpoC
Ordered Locus Names:	BH0127

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	1206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_01322
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01322
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1206	1206	DNA-directed RNA polymerase subunit beta' HAMAP MF_01322		PRO_0000067706

Sequences

	Sequence		Length	Mass (Da)
	Q9Z9M1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 6CF2DB2AB161FF42	FASTA	1,206	134,928
	10 20 30 40 50 60 MIDVNNFEYM KIGLASPNKI RSWSRGEVKK PETINYRTLK PEKDGLFCER IFGPQKDWEC 70 80 90 100 110 120 HCGKYKRVRY KGVVCDRCGV EVTRAKVRRE RMGHIELAAP VSHIWYFKGI PSRMGLVLDM 130 140 150 160 170 180 SPRSLEEVIY FASYVVTDPG DTPLEKKQLL SEKEFRAYLD KYGRSFTAQM GAEAIRKLLM 190 200 210 220 230 240 DIDLDKEVDG LKEELQTAQG QRRTRAIKRL EVLEAFRNSG NEPSWMILDV LPVIPPELRP 250 260 270 280 290 300 MVQLDGGRFA TSDLNDLYRR VINRNNRLKR LLDLGAPSII VQNEKRMLQE AVDALIDNGR 310 320 330 340 350 360 RGRPVTGPGN RPLKSLSHML KGKQGRFRQN LLGKRVDYSG RSVIVVGPNL KMYQCGLPKE 370 380 390 400 410 420 MALELFKPFV MKELVSKGLA HNIKSAKRKV ERVQPEVWDV LEEVIKEHPV LLNRAPTLHR 430 440 450 460 470 480 LGIQAFEPTL VEGRAIKLHP LVCTAYNADF DGDQMAVHVP LSAEAQAEAR ILMLAAQNIL 490 500 510 520 530 540 NPKDGKPVVT PSQDMVLGNY YLTMEREGAK GEGSVFKDTN EALIAYQNGY VHLHTRIAIP 550 560 570 580 590 600 VASLGKTTFK EEQNSQLLLT TVGKLIFNEI LPESFPYVNE PTAHNLEVET PSKYMVPTST 610 620 630 640 650 660 NVKELFQERD VVAPFKKGFL GNIIAEVFKK FKITETSKML DRMKDLGFKY STKAGITVGV 670 680 690 700 710 720 ADIVVLPEKK EILAEAEKKV DRVLKQFRRG LITEEERYDR VISIWSEAKD VIQDKLMGSL 730 740 750 760 770 780 DKRNPIFMMS DSGARGNASN FTQLAGMRGL MANPSGRIIE LPIKSSFREG LTVLEYFIST 790 800 810 820 830 840 HGARKGLADT ALKTADSGYL TRRLVDVAQD VIVREDDCGT DRGLEVEAIK EGNEIIEGLY 850 860 870 880 890 900 DRLVGRVAFK TVRHPETGEP IVKKNELIHE DLAKQIVEAG VEQVTIRSVF TCDTRHGVCK 910 920 930 940 950 960 KCYGRNLATG SDVEVGEAVG IIAAQSIGEP GTQLTMRTFH TGGVAGDDIT QGLPRIQELF 970 980 990 1000 1010 1020 EARNPKGQAV ITEIEGEVTN INEADKREIT VKGEMETKTY SIPYGARIKV ELGEQVVPGQ 1030 1040 1050 1060 1070 1080 SLTEGSIDPK ELLKVQGMTG VQEYLLREVQ KVYRMQGVEI GDKHVEVMVR QMLRKIRVID 1090 1100 1110 1120 1130 1140 AGDTEVLPGS LIEIQHFNDE NKKVLLSGKR PATGRPVLLG ITKASLETDS FLSAASFQET 1150 1160 1170 1180 1190 1200 TRVLTDAAIK GKRDELVGLK ENVIIGKLVP AGTGMNRYRN LDIVSDYDQQ AVGTEEAVME EAVTTE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a 32-kb region including the major ribosomal protein gene clusters from alkaliphilic Bacillus sp. strain C-125." Takami H., Takaki Y., Nakasone K., Hirama C., Inoue A., Horikoshi K. Biosci. Biotechnol. Biochem. 63:452-455(1999) [PubMed: 10192928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
[2]	"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB017508 Genomic DNA. Translation: BAA75264.1. BA000004 Genomic DNA. Translation: BAB03846.1.
PIR	T44376.
RefSeq	NP_240993.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9Z9M1.
SMR	Q9Z9M1. Positions 10-172.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000050931; EBBACP00000049570; EBBACG00000050922.
GeneID	893610.
GenomeReviews	Gene locus BH0127 in contig BA000004_GR.
KEGG	bha:BH0127.
NMPDR	fig|272558.1.peg.127.
PATRIC	18937126. VBIBacHal18977_0135.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002028.
HOGENOM	HBG621785.
OMA	DINDKHI.
PhylomeDB	Q9Z9M1.
ProtClustDB	PRK00566.
Enzyme and pathway databases
BioCyc	BHAL272558:BH0127-MONOMER.
Family and domain databases
HAMAP	MF_01322. RNApol_bact_RpoC. [Tree]
InterPro	IPR012754. DNA-dir_RpoC_beta_prime. IPR000722. RNA_pol_asu. IPR006592. RNA_pol_N. IPR007080. RNA_pol_Rpb1_1. IPR007066. RNA_pol_Rpb1_3. IPR007083. RNA_pol_Rpb1_4. IPR007081. RNA_pol_Rpb1_5. [Graphical view]
KO	K03046.
Pfam	PF04997. RNA_pol_Rpb1_1. 1 hit. PF00623. RNA_pol_Rpb1_2. 1 hit. PF04983. RNA_pol_Rpb1_3. 1 hit. PF05000. RNA_pol_Rpb1_4. 1 hit. PF04998. RNA_pol_Rpb1_5. 1 hit. [Graphical view]
SMART	SM00663. RPOLA_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02386. RpoC_TIGR. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOC_BACHD

Accession

Primary (citable) accession number: Q9Z9M1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program