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Q9Z9A7

- EFTU_CHLPN

UniProt

Q9Z9A7 - EFTU_CHLPN

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Protein

Elongation factor Tu

Gene

tuf

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-724-MONOMER.
CPNE115713:GHEY-76-MONOMER.
CPNE138677:GH8N-76-MONOMER.
CPNE182082:GH4N-76-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Synonyms:tufA
Ordered Locus Names:CPn_0074, CP_0701, CpB0074
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 394393Elongation factor TuPRO_0000091307Add
BLAST

Proteomic databases

PRIDEiQ9Z9A7.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi115713.CPn0074.

Structurei

3D structure databases

ProteinModelPortaliQ9Z9A7.
SMRiQ9Z9A7. Positions 2-392.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 204195tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1By similarity
Regioni60 – 645G2By similarity
Regioni81 – 844G3By similarity
Regioni136 – 1394G4By similarity
Regioni174 – 1763G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Z9A7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKETFQRNK PHINIGTIGH VDHGKTTLTA AITRALSGDG LASFRDYSSI
60 70 80 90 100
DNTPEEKARG ITINASHVEY ETPNRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSATD GAMPQTKEHI LLARQVGVPY IVVFLNKVDM ISQEDAELID
160 170 180 190 200
LVEMELSELL EEKGYKGCPI IRGSALKALE GDANYIEKVR ELMQAVDDNI
210 220 230 240 250
PTPEREIDKP FLMPIEDVFS ISGRGTVVTG RIERGIVKVS DKVQLVGLGE
260 270 280 290 300
TKETIVTGVE MFRKELPEGR AGENVGLLLR GIGKNDVERG MVVCQPNSVK
310 320 330 340 350
PHTKFKSAVY VLQKEEGGRH KPFFSGYRPQ FFFRTTDVTG VVTLPEGTEM
360 370 380 390
VMPGDNVELD VELIGTVALE EGMRFAIREG GRTIGAGTIS KINA
Length:394
Mass (Da):43,136
Last modified:January 23, 2007 - v3
Checksum:i1463A200385BC4FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18227.1.
AE002161 Genomic DNA. Translation: AAF38509.1.
BA000008 Genomic DNA. Translation: BAA98284.1.
AE009440 Genomic DNA. Translation: AAP98007.1.
PIRiB86500.
F72123.
RefSeqiNP_224282.1. NC_000922.1.
NP_300133.1. NC_002491.1.
NP_445243.1. NC_002179.2.
NP_876350.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18227; AAD18227; CPn_0074.
AAF38509; AAF38509; CP_0701.
AAP98007; AAP98007; CpB0074.
BAA98284; BAA98284; BAA98284.
GeneIDi1466757.
894749.
918864.
963722.
KEGGicpa:CP0701.
cpj:CPj0074.
cpn:CPn0074.
cpt:CpB0074.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18227.1 .
AE002161 Genomic DNA. Translation: AAF38509.1 .
BA000008 Genomic DNA. Translation: BAA98284.1 .
AE009440 Genomic DNA. Translation: AAP98007.1 .
PIRi B86500.
F72123.
RefSeqi NP_224282.1. NC_000922.1.
NP_300133.1. NC_002491.1.
NP_445243.1. NC_002179.2.
NP_876350.1. NC_005043.1.

3D structure databases

ProteinModelPortali Q9Z9A7.
SMRi Q9Z9A7. Positions 2-392.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 115713.CPn0074.

Proteomic databases

PRIDEi Q9Z9A7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD18227 ; AAD18227 ; CPn_0074 .
AAF38509 ; AAF38509 ; CP_0701 .
AAP98007 ; AAP98007 ; CpB0074 .
BAA98284 ; BAA98284 ; BAA98284 .
GeneIDi 1466757.
894749.
918864.
963722.
KEGGi cpa:CP0701.
cpj:CPj0074.
cpn:CPn0074.
cpt:CpB0074.

Phylogenomic databases

eggNOGi COG0050.
HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci CPNE115711:GI7B-724-MONOMER.
CPNE115713:GHEY-76-MONOMER.
CPNE138677:GH8N-76-MONOMER.
CPNE182082:GH4N-76-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry nameiEFTU_CHLPN
AccessioniPrimary (citable) accession number: Q9Z9A7
Secondary accession number(s): Q9JQB9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 104 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3