Q9Z998 (TAL_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	CPn_0083, CP_0692, CpB0083

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.
Sequence caution	The sequence AAF38500.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Transaldolase HAMAP MF_00492		PRO_0000173588
Sites
	Active site	132	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9Z998 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: DAEC1CD904079943	FASTA	327	36,052
	10 20 30 40 50 60 MSNQFDQLKK LSTIVCDSGD PELVKASGSQ DATTNPSLIL KVAQEPKFQE LLNEAVVWGI 70 80 90 100 110 120 RQNGDDLQTL SFILDKIQVN FALEIIKNIP GRISLEIDAR LSFNVEAMVQ RAVFLSQLFE 130 140 150 160 170 180 AMGGDKKRLL VKIPGTWEGI RAVEFLEAKG IACNVTLIFN LVQAIAAAKA KATLISPFVG 190 200 210 220 230 240 RIYDWWIAAY GDEGYSIDAD PGVASVSNIY AYYKKFGIPT QIMAASFRTK EQVLALAGCD 250 260 270 280 290 300 LLTISPKLLD ELKKSQHPVK KELDPAEAKK LDVQPIELTE SFFRFLMNED AMATEKLAEG 310 320 IRIFAGDTQI LETAITEFIK QIAAEGA

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.
[3]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[4]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001363 Genomic DNA. Translation: AAD18236.1. AE002161 Genomic DNA. Translation: AAF38500.1. Different initiation. BA000008 Genomic DNA. Translation: BAA98293.1. AE009440 Genomic DNA. Translation: AAP98016.1.
PIR	C86501. D81550. E72120.
RefSeq	NP_224291.1. NC_000922.1. NP_300142.1. NC_002491.1. NP_445234.1. NC_002179.2. NP_876359.1. NC_005043.1.
3D structure databases
ProteinModelPortal	Q9Z998.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1466766. 895561. 918875. 963207.
GenomeReviews	Gene locus CPn_0083 in contig AE001363_GR. Gene locus CP_0692 in contig AE002161_GR. Gene locus CpB0083 in contig AE009440_GR. Gene locus tal in contig BA000008_GR.
KEGG	cpa:CP0692. cpn:CPn0083. cpt:CpB0083.
TIGR	CP_0692.
Phylogenomic databases
HOGENOM	HBG286747.
OMA	GCEILAI.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0692-MONOMER. CPNE115713:CPN0083-MONOMER. CPNE138677:CPJ0083-MONOMER. CPNE182082:CPB0083-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_CHLPN

Accession

Primary (citable) accession number: Q9Z998
Secondary accession number(s): Q9JQK3, Q9K212

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program