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Q9Z986

- PKND_CHLPN

UniProt

Q9Z986 - PKND_CHLPN

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Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATPUniRule annotation
Active sitei138 – 1381Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-701-MONOMER.
CPNE115713:GHEY-98-MONOMER.
CPNE138677:GH8N-98-MONOMER.
CPNE182082:GH4N-98-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
Gene namesi
Name:pknDUniRule annotation
Ordered Locus Names:CPn_0095, CP_0679, CPj0095, CpB0095
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 932932Serine/threonine-protein kinase PknDPRO_0000171192Add
BLAST

Post-translational modificationi

Autophosphorylated on serine and threonine residues.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0095.

Structurei

3D structure databases

ProteinModelPortaliQ9Z986.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 291288Protein kinaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000034686.
KOiK08884.
OMAiYQMLTLS.
OrthoDBiEOG6W45P7.

Family and domain databases

HAMAPiMF_01957. PknD_kinase.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z986-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERYDIVRII GKGGMGEVYL AYDPVCSRKV ALKKIREDLA ENPLLKRRFL
60 70 80 90 100
REARIAADLI HPGVVPVYTI YSEKDPVYYT MPYIEGYTLK TLLKSVWQKE
110 120 130 140 150
SLSKELAEKT SVGAFLSIFH KICCTIEYVH SRGILHRDLK PDNILLGLFS
160 170 180 190 200
EAVILDWGAA VACGEEEDLL DIDVSKEEVL SSRMTIPGRI VGTPDYMAPE
210 220 230 240 250
RLLGHPASKS TDIYALGVVL YQMLTLSFPY RRKKGKKIVL DGQRIPSPQE
260 270 280 290 300
VAPYREIPPF LSAVVMRMLA VDPQERYSSV TELKEDIESH LKGSPKWTLT
310 320 330 340 350
TALPPKKSSS WKLNEPILLS KYFPMLEVSP ASWYSLAISN IESFSEMRLE
360 370 380 390 400
YTLSKKGLNE GFGILLPTSE NALGGDFYQG YGFWLHIKER TLSVSLVKNS
410 420 430 440 450
LEIQRCSQDL ESDKETFLIA LEQHNHSLSL FVDGTTWLIH MNYLPSRSGR
460 470 480 490 500
VAIIVRDMED ILEDIGIFES SGSLRVSCLA VPDAFLAEKL YDRALVLYRR
510 520 530 540 550
IAESFPGRKE GYEARFRAGI TVLEKASTDN NEQEFALAIE EFSKLHDGVA
560 570 580 590 600
APLEYLGKAL VYQRLQEYNE EIKSLLLALK RYSQHPEIFR LKDHVVYRLH
610 620 630 640 650
ESFYKRDRLA LVFMILVLEI APQAITPGQE EKILVWLKDK SRATLFCLLD
660 670 680 690 700
PTVLELRSSK MELFLSYWSG FIPHLNSLFH RAWDQSDVRA LIEIFYVACD
710 720 730 740 750
LHKWQFLSSC IDIFKESLED QKATEEIVEF SFEDLGAFLF AIQSIFNKED
760 770 780 790 800
AEKIFVSNDQ LSPILLVYIF DLFANRALLE SQGEAIFQAL DLIRSKVPEN
810 820 830 840 850
FYHDYLRNHE IRAHLWCRNE KALSTIFENY TEKQLKDEQH ELFVLYGCYL
860 870 880 890 900
ALIQGAEAAK QHFDVCREDR IFPASLLARN YNRLGLPKDA LSYQERRLLL
910 920 930
RQKFLYFHCL GNHDERDLCQ TMYHLLTEEF QL
Length:932
Mass (Da):107,410
Last modified:July 11, 2001 - v2
Checksum:i47AAF87DF6CC5DF7
GO

Sequence cautioni

The sequence AAD18248.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAA98305.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18248.1. Different initiation.
AE002161 Genomic DNA. Translation: AAF73695.1.
BA000008 Genomic DNA. Translation: BAA98305.1. Different initiation.
AE009440 Genomic DNA. Translation: AAP98028.1.
PIRiC72120.
G86502.
RefSeqiNP_300154.2. NC_002491.1.
NP_445221.1. NC_002179.2.
NP_876371.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18248; AAD18248; CPn_0095.
AAF73695; AAF73695; CP_0679.
AAP98028; AAP98028; CpB0095.
BAA98305; BAA98305; BAA98305.
GeneIDi1466778.
918839.
963217.
KEGGicpa:CP0679.
cpj:CPj0095.
cpt:CpB0095.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18248.1 . Different initiation.
AE002161 Genomic DNA. Translation: AAF73695.1 .
BA000008 Genomic DNA. Translation: BAA98305.1 . Different initiation.
AE009440 Genomic DNA. Translation: AAP98028.1 .
PIRi C72120.
G86502.
RefSeqi NP_300154.2. NC_002491.1.
NP_445221.1. NC_002179.2.
NP_876371.1. NC_005043.1.

3D structure databases

ProteinModelPortali Q9Z986.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 115713.CPn0095.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD18248 ; AAD18248 ; CPn_0095 .
AAF73695 ; AAF73695 ; CP_0679 .
AAP98028 ; AAP98028 ; CpB0095 .
BAA98305 ; BAA98305 ; BAA98305 .
GeneIDi 1466778.
918839.
963217.
KEGGi cpa:CP0679.
cpj:CPj0095.
cpt:CpB0095.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000034686.
KOi K08884.
OMAi YQMLTLS.
OrthoDBi EOG6W45P7.

Enzyme and pathway databases

BioCyci CPNE115711:GI7B-701-MONOMER.
CPNE115713:GHEY-98-MONOMER.
CPNE138677:GH8N-98-MONOMER.
CPNE182082:GH4N-98-MONOMER.

Family and domain databases

HAMAPi MF_01957. PknD_kinase.
InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry nameiPKND_CHLPN
AccessioniPrimary (citable) accession number: Q9Z986
Secondary accession number(s): Q9K216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: July 11, 2001
Last modified: October 1, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3