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Q9Z986 (PKND_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknD

EC=2.7.11.1
Gene names
Name:pknD
Ordered Locus Names:CPn_0095, CP_0679, CPj0095, CpB0095
OrganismChlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]
Taxonomic identifier83558 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length932 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth By similarity. HAMAP-Rule MF_01957

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. HAMAP-Rule MF_01957

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity. HAMAP-Rule MF_01957

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAD18248.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAA98305.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 932932Serine/threonine-protein kinase PknD HAMAP-Rule MF_01957
PRO_0000171192

Regions

Domain4 – 291288Protein kinase
Nucleotide binding10 – 189ATP By similarity

Sites

Active site1381Proton acceptor By similarity
Binding site331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Z986 [UniParc].

Last modified July 11, 2001. Version 2.
Checksum: 47AAF87DF6CC5DF7

FASTA932107,410
        10         20         30         40         50         60 
MERYDIVRII GKGGMGEVYL AYDPVCSRKV ALKKIREDLA ENPLLKRRFL REARIAADLI 

        70         80         90        100        110        120 
HPGVVPVYTI YSEKDPVYYT MPYIEGYTLK TLLKSVWQKE SLSKELAEKT SVGAFLSIFH 

       130        140        150        160        170        180 
KICCTIEYVH SRGILHRDLK PDNILLGLFS EAVILDWGAA VACGEEEDLL DIDVSKEEVL 

       190        200        210        220        230        240 
SSRMTIPGRI VGTPDYMAPE RLLGHPASKS TDIYALGVVL YQMLTLSFPY RRKKGKKIVL 

       250        260        270        280        290        300 
DGQRIPSPQE VAPYREIPPF LSAVVMRMLA VDPQERYSSV TELKEDIESH LKGSPKWTLT 

       310        320        330        340        350        360 
TALPPKKSSS WKLNEPILLS KYFPMLEVSP ASWYSLAISN IESFSEMRLE YTLSKKGLNE 

       370        380        390        400        410        420 
GFGILLPTSE NALGGDFYQG YGFWLHIKER TLSVSLVKNS LEIQRCSQDL ESDKETFLIA 

       430        440        450        460        470        480 
LEQHNHSLSL FVDGTTWLIH MNYLPSRSGR VAIIVRDMED ILEDIGIFES SGSLRVSCLA 

       490        500        510        520        530        540 
VPDAFLAEKL YDRALVLYRR IAESFPGRKE GYEARFRAGI TVLEKASTDN NEQEFALAIE 

       550        560        570        580        590        600 
EFSKLHDGVA APLEYLGKAL VYQRLQEYNE EIKSLLLALK RYSQHPEIFR LKDHVVYRLH 

       610        620        630        640        650        660 
ESFYKRDRLA LVFMILVLEI APQAITPGQE EKILVWLKDK SRATLFCLLD PTVLELRSSK 

       670        680        690        700        710        720 
MELFLSYWSG FIPHLNSLFH RAWDQSDVRA LIEIFYVACD LHKWQFLSSC IDIFKESLED 

       730        740        750        760        770        780 
QKATEEIVEF SFEDLGAFLF AIQSIFNKED AEKIFVSNDQ LSPILLVYIF DLFANRALLE 

       790        800        810        820        830        840 
SQGEAIFQAL DLIRSKVPEN FYHDYLRNHE IRAHLWCRNE KALSTIFENY TEKQLKDEQH 

       850        860        870        880        890        900 
ELFVLYGCYL ALIQGAEAAK QHFDVCREDR IFPASLLARN YNRLGLPKDA LSYQERRLLL 

       910        920        930 
RQKFLYFHCL GNHDERDLCQ TMYHLLTEEF QL 

« Hide

References

[1]"Comparative genomes of Chlamydia pneumoniae and C. trachomatis."
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.
Nat. Genet. 21:385-389(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CWL029.
[2]"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39."
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. expand/collapse author list , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.
Nucleic Acids Res. 28:1397-1406(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AR39.
[3]"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J138.
[4]"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TW-183.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001363 Genomic DNA. Translation: AAD18248.1. Different initiation.
AE002161 Genomic DNA. Translation: AAF73695.1.
BA000008 Genomic DNA. Translation: BAA98305.1. Different initiation.
AE009440 Genomic DNA. Translation: AAP98028.1.
PIRC72120.
G86502.
RefSeqNP_300154.2. NC_002491.1.
NP_445221.1. NC_002179.2.
NP_876371.1. NC_005043.1.

3D structure databases

ProteinModelPortalQ9Z986.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING115713.CPn0095.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD18248; AAD18248; CPn_0095.
AAF73695; AAF73695; CP_0679.
AAP98028; AAP98028; CpB0095.
BAA98305; BAA98305; BAA98305.
GeneID1466778.
918839.
963217.
KEGGcpa:CP0679.
cpj:CPj0095.
cpt:CpB0095.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000034686.
KOK08884.
OMAYQMLTLS.
OrthoDBEOG6W45P7.

Enzyme and pathway databases

BioCycCPNE115711:GI7B-701-MONOMER.
CPNE115713:GHEY-98-MONOMER.
CPNE138677:GH8N-98-MONOMER.
CPNE182082:GH4N-98-MONOMER.

Family and domain databases

HAMAPMF_01957. PknD_kinase.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKND_CHLPN
AccessionPrimary (citable) accession number: Q9Z986
Secondary accession number(s): Q9K216
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: July 11, 2001
Last modified: May 14, 2014
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families