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Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPUniRule annotation1
Active sitei138Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPUniRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
Gene namesi
Name:pknDUniRule annotation
Ordered Locus Names:CPn_0095, CP_0679, CPj0095, CpB0095
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001711921 – 932Serine/threonine-protein kinase PknDAdd BLAST932

Post-translational modificationi

Autophosphorylated on serine and threonine residues.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi182082.CpB0095

Structurei

3D structure databases

ProteinModelPortaliQ9Z986
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 291Protein kinaseUniRule annotationAdd BLAST288

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D9P Bacteria
COG0515 LUCA
HOGENOMiHOG000034686
KOiK12132
OMAiSIFHKIC
OrthoDBiPOG091H0264

Family and domain databases

Gene3Di1.25.40.10, 1 hit
HAMAPiMF_01957 PknD_kinase, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR023507 Ser/Thr_kinase_PknD
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Z986-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERYDIVRII GKGGMGEVYL AYDPVCSRKV ALKKIREDLA ENPLLKRRFL
60 70 80 90 100
REARIAADLI HPGVVPVYTI YSEKDPVYYT MPYIEGYTLK TLLKSVWQKE
110 120 130 140 150
SLSKELAEKT SVGAFLSIFH KICCTIEYVH SRGILHRDLK PDNILLGLFS
160 170 180 190 200
EAVILDWGAA VACGEEEDLL DIDVSKEEVL SSRMTIPGRI VGTPDYMAPE
210 220 230 240 250
RLLGHPASKS TDIYALGVVL YQMLTLSFPY RRKKGKKIVL DGQRIPSPQE
260 270 280 290 300
VAPYREIPPF LSAVVMRMLA VDPQERYSSV TELKEDIESH LKGSPKWTLT
310 320 330 340 350
TALPPKKSSS WKLNEPILLS KYFPMLEVSP ASWYSLAISN IESFSEMRLE
360 370 380 390 400
YTLSKKGLNE GFGILLPTSE NALGGDFYQG YGFWLHIKER TLSVSLVKNS
410 420 430 440 450
LEIQRCSQDL ESDKETFLIA LEQHNHSLSL FVDGTTWLIH MNYLPSRSGR
460 470 480 490 500
VAIIVRDMED ILEDIGIFES SGSLRVSCLA VPDAFLAEKL YDRALVLYRR
510 520 530 540 550
IAESFPGRKE GYEARFRAGI TVLEKASTDN NEQEFALAIE EFSKLHDGVA
560 570 580 590 600
APLEYLGKAL VYQRLQEYNE EIKSLLLALK RYSQHPEIFR LKDHVVYRLH
610 620 630 640 650
ESFYKRDRLA LVFMILVLEI APQAITPGQE EKILVWLKDK SRATLFCLLD
660 670 680 690 700
PTVLELRSSK MELFLSYWSG FIPHLNSLFH RAWDQSDVRA LIEIFYVACD
710 720 730 740 750
LHKWQFLSSC IDIFKESLED QKATEEIVEF SFEDLGAFLF AIQSIFNKED
760 770 780 790 800
AEKIFVSNDQ LSPILLVYIF DLFANRALLE SQGEAIFQAL DLIRSKVPEN
810 820 830 840 850
FYHDYLRNHE IRAHLWCRNE KALSTIFENY TEKQLKDEQH ELFVLYGCYL
860 870 880 890 900
ALIQGAEAAK QHFDVCREDR IFPASLLARN YNRLGLPKDA LSYQERRLLL
910 920 930
RQKFLYFHCL GNHDERDLCQ TMYHLLTEEF QL
Length:932
Mass (Da):107,410
Last modified:July 11, 2001 - v2
Checksum:i47AAF87DF6CC5DF7
GO

Sequence cautioni

The sequence AAD18248 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA98305 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA Translation: AAD18248.1 Different initiation.
AE002161 Genomic DNA Translation: AAF73695.1
BA000008 Genomic DNA Translation: BAA98305.1 Different initiation.
AE009440 Genomic DNA Translation: AAP98028.1
PIRiC72120
G86502
RefSeqiWP_010882745.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD18248; AAD18248; CPn_0095
AAF73695; AAF73695; CP_0679
AAP98028; AAP98028; CpB0095
BAA98305; BAA98305; BAA98305
KEGGicpa:CP_0679
cpj:CPj0095
cpt:CpB0095

Similar proteinsi

Entry informationi

Entry nameiPKND_CHLPN
AccessioniPrimary (citable) accession number: Q9Z986
Secondary accession number(s): Q9K216
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: July 11, 2001
Last modified: March 28, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health