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Q9Z986

- PKND_CHLPN

UniProt

Q9Z986 - PKND_CHLPN

Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 103 (01 Oct 2014)
      Sequence version 2 (11 Jul 2001)
      Previous versions | rss
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    Functioni

    Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei33 – 331ATPUniRule annotation
    Active sitei138 – 1381Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCPNE115711:GI7B-701-MONOMER.
    CPNE115713:GHEY-98-MONOMER.
    CPNE138677:GH8N-98-MONOMER.
    CPNE182082:GH4N-98-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
    Gene namesi
    Name:pknDUniRule annotation
    Ordered Locus Names:CPn_0095, CP_0679, CPj0095, CpB0095
    OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
    Taxonomic identifieri83558 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 932932Serine/threonine-protein kinase PknDPRO_0000171192Add
    BLAST

    Post-translational modificationi

    Autophosphorylated on serine and threonine residues.UniRule annotation

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi115713.CPn0095.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z986.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 291288Protein kinaseUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
    Contains 1 protein kinase domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000034686.
    KOiK08884.
    OMAiYQMLTLS.
    OrthoDBiEOG6W45P7.

    Family and domain databases

    HAMAPiMF_01957. PknD_kinase.
    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z986-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERYDIVRII GKGGMGEVYL AYDPVCSRKV ALKKIREDLA ENPLLKRRFL    50
    REARIAADLI HPGVVPVYTI YSEKDPVYYT MPYIEGYTLK TLLKSVWQKE 100
    SLSKELAEKT SVGAFLSIFH KICCTIEYVH SRGILHRDLK PDNILLGLFS 150
    EAVILDWGAA VACGEEEDLL DIDVSKEEVL SSRMTIPGRI VGTPDYMAPE 200
    RLLGHPASKS TDIYALGVVL YQMLTLSFPY RRKKGKKIVL DGQRIPSPQE 250
    VAPYREIPPF LSAVVMRMLA VDPQERYSSV TELKEDIESH LKGSPKWTLT 300
    TALPPKKSSS WKLNEPILLS KYFPMLEVSP ASWYSLAISN IESFSEMRLE 350
    YTLSKKGLNE GFGILLPTSE NALGGDFYQG YGFWLHIKER TLSVSLVKNS 400
    LEIQRCSQDL ESDKETFLIA LEQHNHSLSL FVDGTTWLIH MNYLPSRSGR 450
    VAIIVRDMED ILEDIGIFES SGSLRVSCLA VPDAFLAEKL YDRALVLYRR 500
    IAESFPGRKE GYEARFRAGI TVLEKASTDN NEQEFALAIE EFSKLHDGVA 550
    APLEYLGKAL VYQRLQEYNE EIKSLLLALK RYSQHPEIFR LKDHVVYRLH 600
    ESFYKRDRLA LVFMILVLEI APQAITPGQE EKILVWLKDK SRATLFCLLD 650
    PTVLELRSSK MELFLSYWSG FIPHLNSLFH RAWDQSDVRA LIEIFYVACD 700
    LHKWQFLSSC IDIFKESLED QKATEEIVEF SFEDLGAFLF AIQSIFNKED 750
    AEKIFVSNDQ LSPILLVYIF DLFANRALLE SQGEAIFQAL DLIRSKVPEN 800
    FYHDYLRNHE IRAHLWCRNE KALSTIFENY TEKQLKDEQH ELFVLYGCYL 850
    ALIQGAEAAK QHFDVCREDR IFPASLLARN YNRLGLPKDA LSYQERRLLL 900
    RQKFLYFHCL GNHDERDLCQ TMYHLLTEEF QL 932
    Length:932
    Mass (Da):107,410
    Last modified:July 11, 2001 - v2
    Checksum:i47AAF87DF6CC5DF7
    GO

    Sequence cautioni

    The sequence AAD18248.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAA98305.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18248.1. Different initiation.
    AE002161 Genomic DNA. Translation: AAF73695.1.
    BA000008 Genomic DNA. Translation: BAA98305.1. Different initiation.
    AE009440 Genomic DNA. Translation: AAP98028.1.
    PIRiC72120.
    G86502.
    RefSeqiNP_300154.2. NC_002491.1.
    NP_445221.1. NC_002179.2.
    NP_876371.1. NC_005043.1.

    Genome annotation databases

    EnsemblBacteriaiAAD18248; AAD18248; CPn_0095.
    AAF73695; AAF73695; CP_0679.
    AAP98028; AAP98028; CpB0095.
    BAA98305; BAA98305; BAA98305.
    GeneIDi1466778.
    918839.
    963217.
    KEGGicpa:CP0679.
    cpj:CPj0095.
    cpt:CpB0095.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18248.1 . Different initiation.
    AE002161 Genomic DNA. Translation: AAF73695.1 .
    BA000008 Genomic DNA. Translation: BAA98305.1 . Different initiation.
    AE009440 Genomic DNA. Translation: AAP98028.1 .
    PIRi C72120.
    G86502.
    RefSeqi NP_300154.2. NC_002491.1.
    NP_445221.1. NC_002179.2.
    NP_876371.1. NC_005043.1.

    3D structure databases

    ProteinModelPortali Q9Z986.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 115713.CPn0095.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD18248 ; AAD18248 ; CPn_0095 .
    AAF73695 ; AAF73695 ; CP_0679 .
    AAP98028 ; AAP98028 ; CpB0095 .
    BAA98305 ; BAA98305 ; BAA98305 .
    GeneIDi 1466778.
    918839.
    963217.
    KEGGi cpa:CP0679.
    cpj:CPj0095.
    cpt:CpB0095.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000034686.
    KOi K08884.
    OMAi YQMLTLS.
    OrthoDBi EOG6W45P7.

    Enzyme and pathway databases

    BioCyci CPNE115711:GI7B-701-MONOMER.
    CPNE115713:GHEY-98-MONOMER.
    CPNE138677:GH8N-98-MONOMER.
    CPNE182082:GH4N-98-MONOMER.

    Family and domain databases

    HAMAPi MF_01957. PknD_kinase.
    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CWL029.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AR39.
    3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
      Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
      Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J138.
    4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
      Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TW-183.

    Entry informationi

    Entry nameiPKND_CHLPN
    AccessioniPrimary (citable) accession number: Q9Z986
    Secondary accession number(s): Q9K216
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2001
    Last sequence update: July 11, 2001
    Last modified: October 1, 2014
    This is version 103 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3