Reviewed, UniProtKB/Swiss-Prot Q9Z942 (RPIA_CHLPN)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase A
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase A
      Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	CPn_0141, CP_0631, CpB0142

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158407

Sequences

	Sequence		Length	Mass (Da)
	Q9Z942-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: C2DD9CFF6F370C17	FASTA	231	25,574
	10 20 30 40 50 60 MEKDLHLHEK KCLAHEAATQ VTSGMILGLG SGSTAKEFIF ALAHRIQTES LAVHAIASSQ 70 80 90 100 110 120 NSYALAKQLA IPLLNPEKFS SLDLTVDGAD EVDPQLRMIK GGGGAIFREK ILLRAAKRSI 130 140 150 160 170 180 ILVDESKLVP VLGKFRVPLE ISRFGRSAII EEIRHLGYEG EWRLQDTGDL FITDSSNYIY 190 200 210 220 230 DIFSPNSYPN PEKDLLKLIQ IHGVIEVGFV IEKVEVWSSN SQGLISKKYS V

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.
[3]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[4]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001363 Genomic DNA. Translation: AAD18294.1. AE002161 Genomic DNA. Translation: AAF38446.1. BA000008 Genomic DNA. Translation: BAA98351.1. AE009440 Genomic DNA. Translation: AAP98075.1.
PIR	B72115. E86508.
RefSeq	NP_224349.1. NP_300200.1. NP_445173.1. NP_876418.1.
3D structure databases
SMR	Q9Z942. Positions 9-224.
ModBase	Search...
Genome annotation databases
GeneID	1466825. 894925. 918930. 963273.
GenomeReviews	Gene locus CPn_0141 in contig AE001363_GR. Gene locus CP_0631 in contig AE002161_GR. Gene locus CpB0142 in contig AE009440_GR. Gene locus rpiA in contig BA000008_GR.
KEGG	cpa:CP0631. cpn:CPn0141. cpt:CpB0142.
TIGR	CP_0631.
Phylogenomic databases
HOGENOM	HBG515603.
OMA	HAIASSQ.
PhylomeDB	Q9Z942.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0631-MONOMER. CPNE115713:CPN0141-MONOMER. CPNE138677:CPJ0141-MONOMER. CPNE182082:CPB0142-MONOMER.
BRENDA	5.3.1.6. 264832.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_CHLPN

Accession

Primary (citable) accession number: Q9Z942
Secondary accession number(s): Q9JQ38

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	February 9, 2010
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)