Q9Z8Z0 (GCP_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	CPn_0194, CP_0573, CpB0197

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303316

Sequences

	Sequence		Length	Mass (Da)
	Q9Z8Z0 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 9C8795AECC20A90A	FASTA	344	36,719
	10 20 30 40 50 60 MLTLGLESSC DETACAIVNE DKQILANIIA SQDIHASYGG VVPELASRAH LHIFPQVINK 70 80 90 100 110 120 ALQQANLLIE DMDLIAVTQT PGLIGSLSVG VHFGKGIAIG AKKSLIGVNH VEAHLYAAYM 130 140 150 160 170 180 AAQNVQFPAL GLVVSGAHTA AFFIENPTSY KLIGKTRDDA IGETFDKVGR FLGLPYPAGP 190 200 210 220 230 240 LIEKLALEGS EDSYPFSPAK VPNYDFSFSG LKTAVLYAIK GNNSSPRSPA PEISLEKQRD 250 260 270 280 290 300 IAASFQKAAC TTIAQKLPTI IKEFSCRSIL IGGGVAINEY FRSAIQTACN LPVYFPPAKL 310 320 330 340 CSDNAAMIAG LGGENFQKNS SIPEIRICAR YQWESVSPFS LASP

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[3]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.
[4]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001363 Genomic DNA. Translation: AAD18347.1. AE002161 Genomic DNA. Translation: AAF73688.1. AE009440 Genomic DNA. Translation: AAP98130.1. BA000008 Genomic DNA. Translation: BAA98404.1.
PIR	B86515. H72106.
RefSeq	NP_224403.1. NC_000922.1. NP_300253.1. NC_002491.1. NP_445116.1. NC_002179.2. NP_876473.1. NC_005043.1.
3D structure databases
ProteinModelPortal	Q9Z8Z0.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1466880. 895167. 918990. 963718.
GenomeReviews	Gene locus CPn_0194 in contig AE001363_GR. Gene locus CP_0573 in contig AE002161_GR. Gene locus CpB0197 in contig AE009440_GR. Gene locus gcp in contig BA000008_GR.
KEGG	cpa:CP0573. cpn:CPn0194. cpt:CpB0197.
TIGR	CP_0573.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0573-MONOMER. CPNE115713:CPN0194-MONOMER. CPNE138677:CPJ0194-MONOMER. CPNE182082:CPB0197-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_CHLPN

Accession

Primary (citable) accession number: Q9Z8Z0
Secondary accession number(s): Q7AJ73, Q7BXQ8, Q7DEH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program